- Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome
[作者：Saulnier, DM; Riehle, K; Mistretta, TA; Diaz, MA; Mandal, D; Raza, S; Weidler, EM; Qin, X; Coarfa, C; Milosavljevic, A; Petrosino, JF; Highlander, S; Gibbs, R; Lynch, SV; Shulman, RJ; Versalovic, J,期刊：Gastroenterology, 页码：1782-1791 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: The intestinal microbiomes of healthy children and pediatric patients with irritable bowel syndrome (IBS) are not well defined. Studies in adults have indicated that the gastrointestinal microbiota cou...
- Global and Deep Molecular Analysis of Microbiota Signatures in Fecal Samples From Patients With Irritable Bowel Syndrome
[作者：Rajilic-Stojanovic, M; Biagi, E; Heilig, HGHJ; Kajander, K; Kekkonen, RA; Tims, S; de Vos, WM,期刊：Gastroenterology, 页码：1792-1801 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Irritable bowel syndrome (IBS) has been associated with disruptions to the intestinal microbiota, but studies have had limited power, coverage, and depth of analysis. We aimed to define microbial popul...
- Preferential Expression of Integrin alpha v beta 8 Promotes Generation of Regulatory T Cells by Mouse CD103(+) Dendritic Cells
[作者：Paidassi, H; Acharya, M; Zhang, AL; Mukhopadhyay, S; Kwon, M; Chow, C; Stuart, LM; Savill, J; Lacy-Hulbert, A,期刊：Gastroenterology, 页码：1813-1820 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Immune responses in the intestine are controlled by regulatory T cells (Tregs), which prevent inflammation in response to commensal bacteria. A specific population of intestinal dendritic cells (DCs), ...
- Retinoic Acid Attenuates Ileitis by Restoring the Balance Between T-Helper 17 and T Regulatory Cells
[作者：Collins, CB; Aherne, CM; Kominsky, D; McNamee, EN; Lebsack, MDP; Eltzschig, H; Jedlicka, P; Rivera-Nieves, J,期刊：Gastroenterology, 页码：1821-1831 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Retinoic acid (RA), produced by intestinal epithelial cells (IECs) and dendritic cells (DCs) promotes the induction of regulatory T cells (Tregs) and decreases the induction of T-helper (Th)17 cells. M...
- Chronic Intestinal Inflammation Induces Stress-Response Genes in Commensal Escherichia coli
[作者：Patwa, LG; Fan, TJ; Tchaptchet, S; Liu, Y; Lussier, YA; Sartor, RB; Hansen, JJ,期刊：Gastroenterology, 页码：1842-U411 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Intestinal microbes induce homeostatic mucosal immune responses, but can also cause inappropriate immune activation in genetically susceptible hosts. Although immune responses to bacterial products hav...
- Cathelicidin Signaling via the Toll-like Receptor Protects Against Colitis in Mice
[作者：Koon, HW; Shih, DQ; Chen, J; Bakirtzi, K; Hing, TC; Law, I; Ho, S; Ichikawa, R; Zhao, DZ; Xu, H; Gallo, R; Dempsey, P; Cheng, GH; Targan, SR; Pothoulakis, C,期刊：Gastroenterology, 页码：1852-U426 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Cathelicidin (encoded by Camp) is an antimicrobial peptide in the innate immune system. We examined whether macrophages express cathelicidin in colons of mice with experimental colitis and patients wit...
- Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR(2)-Dependent Mechanism in Mice
[作者：Cattaruzza, F; Lyo, V; Jones, E; Pham, D; Hawkins, J; Kirkwood, K; Valdez-Morales, E; Ibeakanma, C; Vanner, SJ; Bogyo, M; Bunnett, NW,期刊：Gastroenterology, 页码：1864-U440 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Although proteases control inflammation and pain, the identity, cellular origin, mechanism of action, and causative role of proteases that are activated during disease are not defined. We investigated ...
- Interleukin-35 Mediates Mucosal Immune Responses That Protect Against T-Cell-Dependent Colitis
[作者：Wirtz, S; Billmeier, U; Mchedlidze, T; Blumberg, RS; Neurath, MF,期刊：Gastroenterology, 页码：1875-1886 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: The soluble hematopoietin receptor Epstein-Barr virus-induced protein (EBI)-3 is an immune regulator that has been associated with the pathogenesis of inflammatory bowel disease. However, the concept t...
- Loss of Interleukin-10 or Transforming Growth Factor beta Signaling in the Human Colon Initiates a T-Helper 1 Response Via Distinct Pathways
[作者：Jarry, A; Bossard, C; Sarrabayrouse, G; Mosnier, JF; Laboisse, CL,期刊：Gastroenterology, 页码：1887-U464 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: Signaling via interleukin (IL)-10 or transforming growth factor (TGF)-beta is disrupted in subpopulations of patients with inflammatory bowel disease, but it is not clear how a T-helper (Th) 1 cell res...
- A Proinflammatory Role for Interleukin-22 in the Immune Response to Hepatitis B Virus
[作者：Zhang, Y; Cobleigh, MA; Lian, JQ; Huang, CX; Booth, CJ; Bai, XF; Robek, MD,期刊：Gastroenterology, 页码：1897-1906 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: T-helper (Th) 17 cells that secrete interleukin (IL)-22 have immunomodulatory and protective properties in the liver and other tissues. IL-22 induces expression of proinflammatory genes but is also mit...
- Iron Regulation of Hepcidin Despite Attenuated Smad1,5,8 Signaling in Mice Without Transferrin Receptor 2 or Hfe
[作者：Corradini, E; Rozier, M; Meynard, D; Odhiambo, A; Lin, HY; Feng, Q; Migas, MC; Britton, RS; Babitt, JL; Fleming, RE,期刊：Gastroenterology, 页码：1907-1914 , 文章类型： Article，,卷期：2011年141-5]
- BACKGROUND & AIMS: HFE and transferrin receptor 2 (TFR2) are each necessary for the normal relationship between body iron status and liver hepcidin expression. In murine Hfe and Tfr2 knockout models of hereditary hemochr...
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