- Spinal Microglia Initiate and Maintain Hyperalgesia in a Rat Model of Chronic Pancreatitis
[作者:Liu, PY; Lu, CL; Wang, CC; Lee, IH; Hsieh, JC; Chen, CC; Lee, HF; Lin, HC; Chang, FY; Lee, SD,期刊:Gastroenterology, 页码:165-U342 , 文章类型: Article,,卷期:2012年142-1]
- BACKGROUND & AIMS: The chronic, persistent pain associated with chronic pancreatitis (CP) has many characteristics of neuropathic pain, initiated and maintained by the activation of spinal microglia. We investigated whet...
- Tamoxifen Induces Rapid, Reversible Atrophy, and Metaplasia in Mouse Stomach
[作者:Huh, WJ; Khurana, SS; Geahlen, JH; Kohli, K; Waller, RA; Mills, JC,期刊:Gastroenterology, 页码:21-U105 , 文章类型: Article,,卷期:2012年142-1]
- Tamoxifen, a selective estrogen receptor modulator, is widely used in research and clinically in patients. We find that treatment of normal mice with a single >= 3 mg/20 g body weight dose of tamoxifen leads to apoptosis...
- Frequent Aneuploidy Among Normal Human Hepatocytes
[作者:Duncan, AW; Newell, AEH; Smith, L; Wilson, EM; Olson, SB; Thayer, MJ; Strom, SC; Grompe, M,期刊:Gastroenterology, 页码:25-28 , 文章类型: Article,,卷期:2012年142-1]
- Murine hepatocytes become polyploid and then undergo ploidy reversal and become aneuploid in a dynamic process called the ploidy conveyor. Although polyploidization occurs in some types of human cells, the degree of aneu...
- Targeting Unlesioned Pharyngeal Motor Cortex Improves Swallowing in Healthy Individuals and After Dysphagic Stroke
[作者:Michou, E; Mistry, S; Jefferson, S; Singh, S; Rothwell, J; Hamdy, S,期刊:Gastroenterology, 页码:29-38 , 文章类型: Editorial Material,,卷期:2012年142-1]
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- Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review
[作者:Molodecky, NA; Soon, IS; Rabi, DM; Ghali, WA; Ferris, M; Chernoff, G; Benchimol, EI; Panaccione, R; Ghosh, S; Barkema, HW; Kaplan, GG,期刊:Gastroenterology, 页码:46-U180 , 文章类型: Review,,卷期:2012年142-1]
- BACKGROUND & AIMS: We conducted a systematic review to determine changes in the worldwide incidence and prevalence of ulcerative colitis (UC) and Crohn's disease (CD) in different regions and with time. METHODS: We perfo...
- Helminth Infection Does Not Reduce Risk for Chronic Inflammatory Disease in a Population-Based Cohort Study
[作者:Bager, P; Hansen, AV; Wohlfahrt, J; Melbye, M,期刊:Gastroenterology, 页码:55-62 , 文章类型: Article,,卷期:2012年142-1]
- BACKGROUND & AIMS: Parasitic helminth infections can suppress symptoms of allergy, type 1 diabetes, arthritis, and inflammatory bowel disease in animal models. We analyzed data from a large, population-based cohort study...
- Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped
[作者:Louis, E; Mary, JY; Vernier-Massouille, G; Grimaud, JC; Bouhnik, Y; Laharie, D; Dupas, JL; Pillant, H; Picon, L; Veyrac, M; Flamant, M; Savoye, G; Jian, R; Devos, M; Porcher, R; Paintaud, G; Piver, E; Colombel, JF; Lemann, M,期刊:Gastroenterology, 页码:63-U201 , 文章类型: Article,,卷期:2012年142-1]
- BACKGROUND & AIMS: It is important to determine whether infliximab therapy can be safely interrupted in patients with Crohn's disease who have undergone a period of prolonged remission. We assessed the risk of relapse af...
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