- ATM-Mediated DNA Damage Signals Mediate Immune Escape through Integrin-alpha v beta 3-Dependent Mechanisms
[作者:Jinushi, M; Chiba, S; Baghdadi, M; Kinoshita, I; Dosaka-Akita, H; Ito, K; Yoshiyama, H; Yagita, H; Uede, T; Takaoka, A,期刊:Cancer research, 页码:56-65 , 文章类型: Article,,卷期:2012年72-1]
- Although the tumor microenvironment plays a critical role in tumor progression and metastasis, the relationship between chemotherapy resistance and modulation of the tumor microenvironment remains unclear. Here, we repor...
- A Dynamic Inflammatory Cytokine Network in the Human Ovarian Cancer Microenvironment
[作者:Kulbe, H; Chakravarty, P; Leinster, DA; Charles, KA; Kwong, J; Thompson, RG; Coward, JI; Schioppa, T; Robinson, SC; Gallagher, WM; Galletta, L; Salako, MA; Smyth, JF; Hagemann, T; Brennan, DJ; Bowtell, DD; Balkwill, FR,期刊:Cancer research, 页码:66-75 , 文章类型: Article,,卷期:2012年72-1]
- Constitutive production of inflammatory cytokines is a characteristic of many human malignant cell lines; however, the in vitro and in vivo interdependence of these cytokines, and their significance to the human cancer m...
- Activated STAT5 Promotes Long-Lived Cytotoxic CD8(+) T Cells That Induce Regression of Autochthonous Melanoma
[作者:Grange, M; Buferne, M; Verdeil, G; Leserman, L; Schmitt-Verhulst, AM; Auphan-Anezin, N,期刊:Cancer research, 页码:76-87 , 文章类型: Article,,卷期:2012年72-1]
- Immunotherapy based on adoptive transfer of tumor antigen-specific CD8(+) T cell (TC) is generally limited by poor in vivo expansion and tumor infiltration. In this study, we report that activated STAT5 transcription fac...
- GLI1 Inhibition Promotes Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells
[作者:Joost, S; Almada, LL; Rohnalter, V; Holz, PS; Vrabel, AM; Fernandez-Barrena, MG; McWilliams, RR; Krause, M; Fernandez-Zapico, ME; Lauth, M,期刊:Cancer research, 页码:88-99 , 文章类型: Article,,卷期:2012年72-1]
- The Hedgehog (HH) pathway has been identified as an important deregulated signal transduction pathway in pancreatic ductal adenocarcinoma (PDAC), a cancer type characterized by a highly metastatic phenotype. In PDAC, the...
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