- Basic Clinical and Laboratory Features of Filoviral Hemorrhagic Fever
[作者:Kortepeter, MG; Bausch, DG; Bray, M,期刊:Journal of Infectious Diseases, 页码:S810-S816 , 文章类型: Article,,卷期:2011年204-supl]
- The filoviruses Marburg and Ebola cause severe hemorrhagic fever (HF) in humans. Beginning with the 1967 Marburg outbreak, 30 epidemics, isolated cases, and accidental laboratory infections have been described in the med...
- Impact of Ebola Mucin-Like Domain on Antiglycoprotein Antibody Responses Induced by Ebola Virus-Like Particles
[作者:Martinez, O; Tantral, L; Mulherkar, N; Chandran, K; Basler, CF,期刊:Journal of Infectious Diseases, 页码:S825-S832 , 文章类型: Article,,卷期:2011年204-supl]
- Ebola virus (EBOV) glycoprotein (GP), responsible for mediating host-cell attachment and membrane fusion, contains a heavily glycosylated mucin-like domain hypothesized to shield GP from neutralizing antibodies. To test ...
- Unconventional Secretion of Ebola Virus Matrix Protein VP40
[作者:Reynard, O; Reid, S; Page, A; Mateo, M; Alazard-Dany, N; Raoul, H; Basler, CF; Volchkov, VE,期刊:Journal of Infectious Diseases, 页码:S833-S839 , 文章类型: Article,,卷期:2011年204-supl]
- The Ebola virus matrix protein VP40 plays an essential role in virus assembly and budding. In this study we reveal that transient VP40 expression results in the release into the culture medium of substantial amounts of s...
- Comparative Analysis of Ebola Virus Glycoprotein Interactions With Human and Bat Cells
[作者:Kuhl, A; Hoffmann, M; Muller, MA; Munster, VJ; Gnirss, K; Kiene, M; Tsegaye, TS; Behrens, G; Herrler, G; Feldmann, H; Drosten, C; Pohlmann, S,期刊:Journal of Infectious Diseases, 页码:S840-S849 , 文章类型: Article,,卷期:2011年204-supl]
- Infection with Ebola virus (EBOV) causes hemorrhagic fever in humans with high case-fatality rates. The EBOV-glycoprotein (EBOV-GP) facilitates viral entry and promotes viral release from human cells. African fruit bats ...
- The Ebola Virus Glycoprotein and HIV-1 Vpu Employ Different Strategies to Counteract the Antiviral Factor Tetherin
[作者:Kuhl, A; Banning, C; Marzi, A; Votteler, J; Steffen, I; Bertram, S; Glowacka, I; Konrad, A; Sturzl, M; Guo, JT; Schubert, U; Feldmann, H; Behrens, G; Schindler, M; Pohlmann, S,期刊:Journal of Infectious Diseases, 页码:S850-S860 , 文章类型: Article,,卷期:2011年204-supl]
- The antiviral protein tetherin/BST2/CD317/HM1.24 restricts cellular egress of human immunodeficiency virus (HIV) and of particles mimicking the Ebola virus (EBOV), a hemorrhagic fever virus. The HIV-1 viral protein U (Vp...
- Identification of Amino Acids in Marburg Virus VP40 That Are Important for Virus-Like Particle Budding
[作者:Makino, A; Yamayoshi, S; Shinya, K; Noda, T; Kawaoka, Y,期刊:Journal of Infectious Diseases, 页码:S871-S877 , 文章类型: Article,,卷期:2011年204-supl]
- The matrix protein VP40 of Marburg virus promotes the formation and release of virus-like particles (VLPs). Marburg virus VP40 interacts with cellular Tsg101 via its L domain motif; however, mutation of this motif does n...
- The Importance of the NP: VP35 Ratio in Ebola Virus Nucleocapsid Formation
[作者:Noda, T; Kolesnikova, L; Becker, S; Kawaoka, Y,期刊:Journal of Infectious Diseases, 页码:S878-S883 , 文章类型: Article,,卷期:2011年204-supl]
- Ebola virus VP35 is a cofactor of the viral RNA polymerase complex and, together with NP and VP24, is an essential component for nucleocapsid formation. In the present study, we examined the interactions between VP35 and...
- Conserved Proline-Rich Region of Ebola Virus Matrix Protein VP40 Is Essential for Plasma Membrane Targeting and Virus-Like Particle Release
[作者:Reynard, O; Nemirov, K; Page, A; Mateo, M; Raoul, H; Weissenhorn, W; Volchkov, VE,期刊:Journal of Infectious Diseases, 页码:S884-S891 , 文章类型: Article,,卷期:2011年204-supl]
- The matrix protein VP40 is essential for Ebola virus (EBOV) and Marburg virus assembly and budding at the plasma membrane. In this study we have investigated the effect of single amino acid substitutions in a conserved p...
- Knockdown of Ebola Virus VP24 Impairs Viral Nucleocapsid Assembly and Prevents Virus Replication
[作者:Mateo, M; Carbonnelle, C; Martinez, MJ; Reynard, O; Page, A; Volchkova, VA; Volchkov, VE,期刊:Journal of Infectious Diseases, 页码:S892-S896 , 文章类型: Article,,卷期:2011年204-supl]
- The structural protein VP24 of Ebola virus (EBOV) is a determinant of virulence in rodent models and possesses an interferon antagonist function. In this study, we investigate the role of VP24 in EBOV replication using R...
- sGP Serves as a Structural Protein in Ebola Virus Infection
[作者:Iwasa, A; Shimojima, M; Kawaoka, Y,期刊:Journal of Infectious Diseases, 页码:S897-S903 , 文章类型: Article,,卷期:2011年204-supl]
- Methods. We expressed ZEBOV GP(1,2), VP40, and NP proteins, together with sGP protein, from expression plasmids and examined the resultant virus-like particles by using Western blot. Cells expressing GP(2) in combination...
- DRBP76 Associates With Ebola Virus VP35 and Suppresses Viral Polymerase Function
[作者:Shabman, RS; Leung, DW; Johnson, J; Glennon, N; Gulcicek, EE; Stone, KL; Leung, L; Hensley, L; Amarasinghe, GK; Basler, CF,期刊:Journal of Infectious Diseases, 页码:S911-S918 , 文章类型: Article,,卷期:2011年204-supl]
- The Zaire Ebola virus (EBOV) protein VP35 is multifunctional; it inhibits IFN-alpha/beta production and functions as a cofactor of the viral RNA polymerase. Mass spectrometry identified the double stranded RNA binding pr...
- Contribution of Sec61 alpha to the Life Cycle of Ebola Virus
[作者:Iwasa, A; Halfmann, P; Noda, T; Oyama, M; Kozuka-Hata, H; Watanabe, S; Shimojima, M; Watanabe, T; Kawaoka, Y,期刊:Journal of Infectious Diseases, 页码:S919-S926 , 文章类型: Article,,卷期:2011年204-supl]
- Background. Similar to other viruses, the viral proteins of Ebola virus (EBOV) interact with a variety of host proteins for its replication. Of the 7 structural proteins encoded in the EBOV genome, VP24 is the smallest a...
- Phosphorylation of Marburg Virus NP Region II Modulates Viral RNA Synthesis
[作者:DiCarlo, A; Biedenkopf, N; Hartlieb, B; Klussmeier, A; Becker, S,期刊:Journal of Infectious Diseases, 页码:S927-S933 , 文章类型: Article,,卷期:2011年204-supl]
- Phosphorylation of the Marburg virus nucleoprotein NP is distributed over 7 regions (I-VII) in its C-terminus. The exact localization of phosphorylated amino acids and function of NP phosphorylation are unknown. Here, we...
|