Salts of the charge-delocalised cations of the triaminocyclopropenium (tac) family bearing alkyl substituents have been prepared and shown to be air- and water-stable ionic liquids.
A highly divergent synthesis of alpha-fuco-, alpha-6-deoxy-allo-, alpha-6-deoxy-altro-pyranosides has been achieved. This route utilizes a Wharton rearrangement as part of a new post-glycosylation transformation strategy...
The reduction of unactivated esters using samarium diiodide is reported for the first time. The optimised protocol allows for the reduction of primary, secondary and tertiary alkyl esters in excellent yields and is compe...
Palladium-catalyzed aerobic oxidative cross-couplings of indoles and benzene have been achieved by using 4,5-diazafluorene derivatives as ancillary ligands. Proper choice of the neutral and anionic ligands enables contro...
Clostridium difficile strain ribotype 027 is a hypervirulent pathogen that is responsible for recent, severe outbreaks of serious nosocomial infections. As a foundation for the development of a preventative carbohydrate-...
A one-pot Yb(III)-mediated cascade reaction has been developed leading to small molecules based on a novel structural motif, i.e. quinazolin-4-one moiety fused with an isoquinoline ring, for potential inhibition of TNF-a...
A small library of glyco-fused benzopyran compounds has been synthesised. Their interaction features with A beta peptides have been characterised by using STD-NMR and trNOESY experiments. The conformational analysis of t...
A fluorophore labeled oligonucleotide could induce aggregation of a positively charged perylene probe. The perylene aggregate could very efficiently quench the fluorescence of the labeled fluorophore. Based on this obser...
A color distinctive, ratiometric pH sensor was demonstrated using pH responsive and fluorescent (PyMMP-b-P2VP) diblock copolymer coated CdSe/ZnS QDs. Due to the change in the P2VP conformations in response to pH change, ...
Exceptional high quality ZIF-8 membranes prepared through a novel seeded growth method in aqueous solutions at near room temperature exhibit excellent separation performance for C2/C3 hydrocarbon mixtures. The separation...
An efficient Lewis acid-catalyzed cyclopropane ring-opening/Friedel-Crafts alkylation sequence of methyl 1-(1H-indole-carbonyl)-1-cyclopropanecarboxylates is reported. The protocol affords functionalized hydropyrido[1,2-...
Reported herein is the discovery of a novel family of "clicked" estradiol-based LMWGs whose gelation ability highly depends on the gelator symmetry. These LMWGs that gel different organic solvents in the presence of H(2)...
A conceptually novel approach to spiro- and dispiroketals of various ring-sizes under neutral conditions has been designed which complements the classical thermodynamically driven tactic. Key steps involved the formation...
Non-mesogenic unit bearing Keggin-type polyoxoanions with tetra-n-octylammonium counterions exhibit an ionic liquid crystalline structure via ionic self-assembly in a certain temperature range.
A pillar[5]arene dimer was synthesized by linking a mono-hydroxylated pillar[5]arene with 1,4-bis(bromomethyl)benzene. The pillar[5]arene dimer formed stronger complexes with n-alkanes than did a monomeric pillar[5]arene...
The charge transfer interactions between reduced graphene oxides and conjugated block copolymers were confirmed by various spectroscopic methods, giving rise to manipulation of the electrical properties of the former.