- Consumption of Large Amounts of Allium Vegetables Reduces Risk for Gastric Cancer in a Meta-analysis
[作者:Zhou, Y; Zhuang, W; Hu, W; Liu, GJ; Wu, TX; Wu, XT,期刊:Gastroenterology, 页码:80-89 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: The chemopreventive effects of Allium vegetables (onions, garlic, shallots, leeks, chives, and so forth) have been studied extensively, although their effect on gastric cancer risk is controversial. We...
- Outcomes of Patients With Crohn's Disease Improved From 1988 to 2008 and Were Associated With Increased Specialist Care
[作者:Nguyen, GC; Nugent, Z; Shaw, S; Bernstein, CN,期刊:Gastroenterology, 页码:90-97 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: We investigated factors that affect long-term outcomes in Crohn's disease (CD). METHODS: We performed a retrospective study of 3403 patients with CD, diagnosed between 1988 and 2008 in Manitoba, Canada...
- High Levels of Folate From Supplements and Fortification Are Not Associated With Increased Risk of Colorectal Cancer
[作者:Stevens, VL; McCullough, ML; Sun, JZ; Jacobs, EJ; Campbell, PT; Gapstur, SM,期刊:Gastroenterology, 页码:98-U174 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Folate intake has been inversely associated with colorectal cancer risk in several prospective epidemiologic studies. However, no study fully assessed the influence of the high levels of folate that ar...
- Nonlinear Reduction in Risk for Colorectal Cancer by Fruit and Vegetable Intake Based on Meta-analysis of Prospective Studies
[作者:Aune, D; Lau, R; Chan, DSM; Vieira, R; Greenwood, DC; Kampman, E; Norat, T,期刊:Gastroenterology, 页码:106-118 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: The association between fruit and vegetable intake and colorectal cancer risk has been investigated by many studies but is controversial because of inconsistent results and weak observed associations. ...
- High-Dose Pegylated Interferon-alpha and Ribavirin in Nonresponder Hepatitis C Patients and Relationship With IL-28B Genotype (SYREN Trial)
[作者:Chevaliez, S; Hezode, C; Soulier, A; Costes, B; Bouvier-Alias, M; Rouanet, S; Foucher, J; Bronowicki, JP; Tran, A; Rosa, I; Mathurin, P; Alric, L; Leroy, V; Couzigou, P; Mallat, A; Charaf-Eddine, M; Babany, G; Pawlotsky, JM,期刊:Gastroenterology, 页码:119-127 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: In patients with chronic hepatitis C who failed to respond to standard therapy, high-dose pegylated interferon (IFN)-alpha and/or ribavirin could induce a stronger antiviral response and prevent treatm...
- Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C
[作者:Honda, M; Takehana, K; Sakai, A; Tagata, Y; Shirasaki, T; Nishitani, S; Muramatsu, T; Yamashita, T; Nakamoto, Y; Mizukoshi, E; Sakai, Y; Yamashita, T; Nakamura, M; Shimakami, T; Yi, M; Lemon, SM; Suzuki, T; Wakita, T; Kaneko, S,期刊:Gastroenterology, 页码:128-U211 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Patients with advanced chronic hepatitis C (CH-C) often are malnourished, but the effects of malnutrition on interferon (IFN) signaling and response to treatment have not been determined. We assessed t...
- A Functional Polymorphism in the Epidermal Growth Factor Gene Is Associated With Risk for Hepatocellular Carcinoma
[作者:Abu Dayyeh, BK; Yang, M; Fuchs, BC; Karl, DL; Yamada, S; Sninsky, JJ; O'Brien, TR; Dienstag, JL; Tanabe, KK; Chung, RT,期刊:Gastroenterology, 页码:141-149 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: A single nucleotide polymorphism 61*G (rs4444903) in the epidermal growth factor (EGF) gene has been associated, in 2 case-control studies, with hepatocellular carcinoma (HCC). We tested associations b...
- Pancreatitis, Pancreatic, and Thyroid Cancer With Glucagon-Like Peptide-1-Based Therapies
[作者:Elashoff, M; Matveyenko, AV; Gier, B; Elashoff, R; Butler, PC,期刊:Gastroenterology, 页码:150-156 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Glucagon-like peptide-1-based therapy is gaining widespread use for type 2 diabetes, although there are concerns about risks for pancreatitis and pancreatic and thyroid cancers. There are also concerns...
- Enteral and Parenteral Nutrition in the Conservative Treatment of Pancreatic Fistula: A Randomized Clinical Trial
[作者:Klek, S; Sierzega, M; Turczynowski, L; Szybinski, P; Szczepanek, K; Kulig, J,期刊:Gastroenterology, 页码:157-U235 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Postoperative pancreatic fistula is the most common and potentially life-threatening complication after pancreatic surgery. Although nutritional support is a key component of conservative therapy in su...
- Serum Response Factor-Dependent MicroRNAs Regulate Gastrointestinal Smooth Muscle Cell Phenotypes
[作者:Park, C; Hennig, GW; Sanders, KM; Cho, JH; Hatton, WJ; Redelman, D; Park, JK; Ward, SM; Miano, JM; Yan, W; Ro, S,期刊:Gastroenterology, 页码:164-175 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Smooth muscle cells (SMCs) change phenotypes under various pathophysiological conditions. These changes are largely controlled by the serum response factor (SRF), a transcription factor that binds to C...
- MyD88 and Retinoic Acid Signaling Pathways Interact to Modulate Gastrointestinal Activities of Dendritic Cells
[作者:Villablanca, EJ; Wang, S; de Calisto, J; Gomes, DCO; Kane, MA; Napoli, JL; Blaner, WS; Kagechika, H; Blomhoff, R; Rosemblatt, M; Bono, MR; von Andrian, UH; Mora, JR,期刊:Gastroenterology, 页码:176-185 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Gut-associated dendritic cells (DC) metabolize vitamin A into all-trans retinoic acid (RA), which is required to induce lymphocytes to localize to the gastrointestinal tract and promotes the differenti...
- Microbial Colonization Induces Dynamic Temporal and Spatial Patterns of NF-kappa B Activation in the Zebrafish Digestive Tract
[作者:Kanther, M; Sun, XL; Muhlbauer, M; Mackey, LC; Flynn, EJ; Bagnat, M; Jobin, C; Rawls, JF,期刊:Gastroenterology, 页码:197-207 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: The nuclear factor kappa-light-chain enhancer of activated B cells (NF-kappa B) transcription factor pathway is activated in response to diverse microbial stimuli to regulate expression of genes involv...
- Defective Leukocyte GM-CSF Receptor (CD116) Expression and Function in Inflammatory Bowel Disease
[作者:Goldstein, JI; Kominsky, DJ; Jacobson, N; Bowers, B; Regalia, K; Austin, GL; Yousefi, M; Falta, MT; Fontenot, AP; Gerich, ME; Golden-Mason, L; Colgan, SP,期刊:Gastroenterology, 页码:208-216 , 文章类型: Article,,卷期:2011年141-1]
- BACKGROUND & AIMS: Inflammatory bowel disease (IBD) refers to 2 chronic inflammatory diseases of the intestine, ie, ulcerative colitis and Crohn's disease. IBD results from environmental factors (eg, bacterial antigens) ...
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