- Protease Inhibitor-Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
[作者：Shimakami, T; Welsch, C; Yamane, D; McGivern, DR; Yi, MK; Zeuzem, S; Lemon, SM,期刊：Gastroenterology, 页码：667-675 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: Several small molecule inhibitors of the hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease have advanced successfully to clinical trials. However, the selection of drug-resistant mutants...
- Gastric Epithelial Stem Cells
[作者：Mills, JC; Shivdasani, RA,期刊：Gastroenterology, 页码：412-424 , 文章类型： Review，,卷期：2011年140-2]
- Advances in our understanding of stem cells in the gastrointestinal tract include the identification of molecular markers of stem and early progenitor cells in the small intestine. Although gastric epithelial stem cells ...
- Spontaneous Control of HCV Is Associated With Expression of HLA-B*57 and Preservation of Targeted Epitopes
[作者：Kim, AY; Kuntzen, T; Timm, J; Nolan, BE; Baca, MA; Reyor, LL; Berical, AC; Feller, AJ; Johnson, KL; Zur Wiesch, JS; Robbins, GK; Chung, RT; Walker, BD; Carrington, M; Allen, TM; Lauer, GM,期刊：Gastroenterology, 页码：686-U434 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: HLA class I alleles are linked to spontaneous control of hepatitis C virus (HCV) and human immunodeficiency virus-1, but for HCV the roles of particular alleles and corresponding CD8(+) T-cell response...
- Hepatic Adenomas Caused by Somatic HNF1A Mutations in Children With Biallelic Mismatch Repair Gene Mutations
[作者：Holter, S; Pollett, A; Zogopoulos, G; Kim, H; Schwenter, F; Asai, K; Gallinger, S; Clendenning, M; Steinbach, G; Jacobson, A; Boycott, KM,期刊：Gastroenterology, 页码：735-736 , 文章类型： Letter，,卷期：2011年140-2]
-
- Budesonide 9 mg Is at Least as Effective as Mesalamine 4.5 g in Patients With Mildly to Moderately Active Crohn's Disease
[作者：Tromm, A; Bunganic, I; Tomsova, E; Tulassay, Z; Lukas, M; Kykal, J; Batovsky, M; Fixa, B; Gabalec, L; Safadi, R; Kramm, HJ; Altorjay, I; Lohr, H; Koutroubakis, I; Bar-Meir, S; Stimac, D; Schaffeler, E; Glasmacher, C; Dilger, K; Mohrbacher, R; Greinwald, R,期刊：Gastroenterology, 页码：425-U123 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: Comparative data on budesonide vs mesalamine for the treatment of mild-to-moderately active Crohn's disease (CD) are sparse. We assessed the efficacy and safety of each therapy in patients with mildly ...
- Genetic Variation in the Prostate Stem Cell Antigen Gene and Upper Gastrointestinal Cancer in White Individuals
[作者：Lochhead, P; Frank, B; Hold, GL; Rabkin, CS; Ng, MTH; Vaughan, TL; Risch, HA; Gammon, MD; Lissowska, J; Weck, MN; Raum, E; Muller, H; Illig, T; Klopp, N; Dawson, A; McColl, KE; Brenner, H; Chow, WH; El-Omar, EM,期刊：Gastroenterology, 页码：435-441 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: An association between gastric cancer and the rs2294008 (C > T) polymorphism in the prostate stem cell antigen (PSCA) gene has been reported for several Asian populations. We set out to determine wheth...
- Type I Interferons Protect From Toll-Like Receptor 9-Associated Liver Injury and Regulate IL-1 Receptor Antagonist in Mice
[作者：Petrasek, J; Dolganiuc, A; Csak, T; Kurt-Jones, EA; Szabo, G,期刊：Gastroenterology, 页码：697-U450 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: Liver inflammation and injury are mediated by the innate immune response, which is regulated by Toll-like receptors (TLR). Activation of TLR9 induces type I interferons (IFNs) via the interferon regula...
- Acycloguanosyl 5 '-thymidyltriphosphate, a Thymidine Analogue Prodrug Activated by Telomerase, Reduces Pancreatic Tumor Growth in Mice
[作者：Polvani, S; Calamante, M; Foresta, V; Ceni, E; Mordini, A; Quattrone, A; D'Amico, M; Luchinat, C; Bertini, I; Galli, A,期刊：Gastroenterology, 页码：709-U471 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: Gemcitabine is the standard of care for metastatic and nonresectable pancreatic tumors. Phase II and III trials have not demonstrated efficacy of recently developed reagents, compared with gemcitabine ...
- The Combination of Ribavirin and Peginterferon Is Superior to Peginterferon and Placebo for Children and Adolescents With Chronic Hepatitis C
[作者：Schwarz, KB; Gonzalez-Peralta, RP; Murray, KF; Molleston, JP; Haber, BA; Jonas, MM; Rosenthal, P; Mohan, P; Balistreri, WF; Narkewicz, MR; Smith, L; Lobritto, SJ; Rossi, S; Valsamakis, A; Goodman, Z; Robuck, PR; Barton, BA,期刊：Gastroenterology, 页码：450-U148 , 文章类型： Article，,卷期：2011年140-2]
- BACKGROUND & AIMS: Although randomized trials of adults infected with hepatitis C virus (HCV) have shown that ribavirin increases the efficacy of pegylated interferon (PEG), such trials have not been performed in childre...
|