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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共98条记录   A Post-entry Step in the Mammalian Orthoreovirus Replication Cycle Is a Determinant of Cell Tropism [作者：Ooms, LS; Kobayashi, T; Dermody, TS; Chappell, JD,期刊：Journal of Biological Chemistry, 页码：41604-41613 , 文章类型： Article，,卷期：2010年285-53] Mammalian reoviruses replicate in a broad range of hosts, cells, and tissues. These viruses display strain-dependent variation in tropism for different types of cells in vivo and ex vivo. Early steps in the reovirus life... Identification of a Residue in Helix 2 of Rice Plasma Membrane Intrinsic Proteins That Influences Water Permeability [作者：Zhang, MH; Lu, SQ; Li, GW; Mao, ZL; Yu, X; Sun, WN; Tang, ZC; Long, MA; Su, WA,期刊：Journal of Biological Chemistry, 页码：41982-41992 , 文章类型： Article，,卷期：2010年285-53] Molecular selection, ion exclusion, and water permeation are well known regulatory mechanisms in aquaporin. Water permeability was found to be diverse in different subgroups of plasma membrane intrinsic proteins (PIPs), ... Proliferating Cell Nuclear Antigen-dependent Rapid Recruitment of Cdt1 and CRL4(Cdt2) at DNA-damaged Sites after UV Irradiation in HeLa Cells [作者：Ishii, T; Shiomi, Y; Takami, T; Murakami, Y; Ohnishi, N; Nishitani, H,期刊：Journal of Biological Chemistry, 页码：41993-42000 , 文章类型： Article，,卷期：2010年285-53] The licensing factor Cdt1 is degraded by CRL4(Cdt2) ubiquitin ligase dependent on proliferating cell nuclear antigen (PCNA) during S phase and when DNA damage is induced in G(1) phase. Association of both Cdt2 and PCNA w... P0 (Protein Zero) Mutation S34C Underlies Instability of Internodal Myelin in S63C Mice [作者：Avila, RL; D'Antonio, M; Bachi, A; Inouye, H; Feltri, ML; Wrabetz, L; Kirschner, DA,期刊：Journal of Biological Chemistry, 页码：42001-42012 , 文章类型： Article，,卷期：2010年285-53] P0 constitutes 50-60% of protein in peripheral nerve myelin and is essential for its structure and stability. Mutations within the P0 gene (MPZ) underlie a variety of hereditary neuropathies. MpzS63C transgenic mice enco... Osmotic Stress Inhibits Proteasome by p38 MAPK-dependent Phosphorylation [作者：Lee, SH; Park, Y; Yoon, SK; Yoon, JB,期刊：Journal of Biological Chemistry, 页码：41280-41289 , 文章类型： Article，,卷期：2010年285-53] Osmotic stress causes profound perturbations of cell functions. Although the adaptive responses required for cell survival upon osmotic stress are being unraveled, little is known about the effects of osmotic stress on u... G Protein beta gamma Gating Confers Volatile Anesthetic Inhibition to Kir3 Channels [作者：Styer, AM; Mirshahi, UL; Wang, CA; Girard, L; Jin, TH; Logothetis, DE; Mirshahi, T,期刊：Journal of Biological Chemistry, 页码：41290-41299 , 文章类型： Article，,卷期：2010年285-53] G protein-activated inwardly rectifying potassium (GIRK or Kir3) channels are directly gated by the beta gamma subunits of G proteins and contribute to inhibitory neurotransmitter signaling pathways. Paradoxically, volat... Ser(120) of Ubc2/Rad6 Regulates Ubiquitin-dependent N-end Rule Targeting by E3 alpha/Ubr1 [作者：Kumar, B; LeCompte, KG; Klein, JM; Haas, AL,期刊：Journal of Biological Chemistry, 页码：41300-41309 , 文章类型： Article，,卷期：2010年285-53] In CHO cells, CDK1/2-dependent phosphorylation of Ubc2/Rad6 at Ser(120) stimulates its ubiquitin conjugating activity and can be replicated by a S120D point mutant (Sarcevic, B., Mawson, A., Baker, R. T., and Sutherland,... Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways [作者：Krause, C; Korchynskyi, O; de Rooij, K; Weidauer, SE; de Gorter, DJJ; van Bezooijen, RL; Hatsell, S; Economides, AN; Mueller, TD; Lowik, CWGM; ten Dijke, P,期刊：Journal of Biological Chemistry, 页码：41614-41626 , 文章类型： Article，,卷期：2010年285-53] Sclerostin is expressed by osteocytes and has catabolic effects on bone. It has been shown to antagonize bone morphogenetic protein (BMP) and/or Wnt activity, although at present the underlying mechanisms are unclear. Co... Decoding Toxicity DEDUCING THE SEQUENCE REQUIREMENTS OF IbsC, A TYPE I TOXIN IN ESCHERICHIA COLI [作者：Mok, WWK; Patel, NH; Li, YF,期刊：Journal of Biological Chemistry, 页码：41627-41636 , 文章类型： Article，,卷期：2010年285-53] Bacterial genomes encode a collection of small peptides that are deleterious to their hosts when overexpressed. The physiological relevance of the majority of these peptides is unknown at present, although many of them h... Enhancement of Reactive Oxygen Species Production and Chlamydial Infection by the Mitochondrial Nod-like Family Member NLRX1 [作者：Abdul-Sater, AA; Said-Sadier, N; Lam, VM; Singh, B; Pettengill, MA; Soares, F; Tattoli, I; Lipinski, S; Girardin, SE; Rosenstiel, P; Ojcius, DM,期刊：Journal of Biological Chemistry, 页码：41637-41645 , 文章类型： Article，,卷期：2010年285-53] Chlamydia trachomatis infections cause severe and irreversible damage that can lead to infertility and blindness in both males and females. Following infection of epithelial cells, Chlamydia induces production of reactiv... Transcription Factor Redundancy Ensures Induction of the Antiviral State [作者：Schmid, S; Mordstein, M; Kochs, G; Garcia-Sastre, A; tenOever, BR,期刊：Journal of Biological Chemistry, 页码：42013-42022 , 文章类型： Article，,卷期：2010年285-53] The transcriptional response to virus infection is thought to be predominantly induced by interferon (IFN) signaling. Here we demonstrate that, in the absence of IFN signaling, an IFN-like transcriptome is still maintain... Deficiency of a Transmembrane Prolyl 4-Hydroxylase in the Zebrafish Leads to Basement Membrane Defects and Compromised Kidney Function [作者：Hyvarinen, J; Parikka, M; Sormunen, R; Ramet, M; Tryggvason, K; Kivirikko, KI; Myllyharju, J; Koivunen, P,期刊：Journal of Biological Chemistry, 页码：42023-42032 , 文章类型： Article，,卷期：2010年285-53] Prolyl 4-hydroxylases (P4Hs) catalyze the hydroxylation of collagens and hypoxia-inducible factor (HIF)-alpha subunits. We studied the zebrafish homologue of the recently characterized human transmembrane P4H (P4H-TM) th... CHIP Promotes Human Telomerase Reverse Transcriptase Degradation and Negatively Regulates Telomerase Activity [作者：Lee, JH; Khadka, P; Baek, SH; Chung, IK,期刊：Journal of Biological Chemistry, 页码：42033-42045 , 文章类型： Article，,卷期：2010年285-53] The maintenance of eukaryotic telomeres requires telomerase, which is minimally composed of a telomerase reverse transcriptase (TERT) and an associated RNA component. Telomerase activity is tightly regulated by expressio... ERK/Ribosomal S6 Kinase (RSK) Signaling Positively Regulates Death Receptor 5 Expression through Co-activation of CHOP and Elk1 [作者：Oh, YT; Liu, XG; Yue, P; Kang, SM; Chen, J; Taunton, J; Khuri, FR; Sun, SY,期刊：Journal of Biological Chemistry, 页码：41310-41319 , 文章类型： Article，,卷期：2010年285-53] Death receptor 5 (DR5) is a death domain-containing transmembrane receptor that triggers apoptosis upon binding to its ligand or when overexpressed. Its expression is induced by certain small molecule drugs, including ce... Cleavage of the NF-kappa B Family Protein p65/RelA by the Chlamydial Protease-like Activity Factor (CPAF) Impairs Proinflammatory Signaling in Cells Infected with Chlamydiae [作者：Christian, J; Vier, J; Paschen, SA; Hacker, G,期刊：Journal of Biological Chemistry, 页码：41320-41327 , 文章类型： Article，,卷期：2010年285-53] Chlamydiae are obligate intracellular bacteria that frequently cause human disease. Chlamydiae replicate in a membranous vacuole in the cytoplasm termed inclusion but have the ability to transport proteins into the host ... The v-myc-induced Q83 Lipocalin Is a Siderocalin [作者：Coudevylle, N; Geist, L; Hotzinger, M; Hartl, M; Kontaxis, G; Bister, K; Konrat, R,期刊：Journal of Biological Chemistry, 页码：41646-41652 , 文章类型： Article，,卷期：2010年285-53] Siderocalins are atypical lipocalins able to capture siderophores with high affinity. They contribute to the innate immune response by interfering with bacterial siderophore-mediated iron uptake but are also involved in ...