- Dysfunctional Gastric Emptying With Down-regulation of Muscle-Specific MicroRNAs in Helicobacter pylori-Infected Mice
[作者:Saito, Y; Suzuki, H; Tsugawa, H; Suzuki, S; Matsuzaki, J; Hirata, K; Hibi, T,期刊:Gastroenterology, 页码:189-198 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Little is known about the pathogenic mechanisms of functional dyspepsia. We investigated the role of microRNAs (miRNAs) in gastric motility disorders associated with Helicobacter pylori infection. METH...
- Tolerance Rather Than Immunity Protects From Helicobacter pylori-Induced Gastric Preneoplasia
[作者:Arnold, IC; Lee, JY; Amieva, MR; Roers, A; Flavell, RA; Sparwasser, T; Muller, A,期刊:Gastroenterology, 页码:199-+ , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Chronic infection with the bacterial pathogen Helicobacter pylori causes gastric disorders, ranging from chronic gastritis to gastric adenocarcinoma. Only a subset of infected persons will develop over...
- Detection of Dysplasia in Barrett's Esophagus With In Vivo Depth-Resolved Nuclear Morphology Measurements
[作者:Terry, NG; Zhu, Y; Rinehart, MT; Brown, WJ; Gebhart, SC; Bright, S; Carretta, E; Ziefle, CG; Panjehpour, M; Galanko, J; Madanick, RD; Dellon, ES; Trembath, D; Bennett, A; Goldblum, JR; Overholt, BF; Woosley, JT; Shaheen, NJ; Wax, A,期刊:Gastroenterology, 页码:42-50 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Patients with Barrett's esophagus (BE) show increased risk of developing esophageal adenocarcinoma and are routinely examined using upper endoscopy with biopsy to detect neoplastic changes. Angle-resol...
- Lack of Commensal Flora in Helicobacter pylori-Infected INS-GAS Mice Reduces Gastritis and Delays Intraepithelial Neoplasia
[作者:Lofgren, JL; Whary, MT; Ge, ZM; Muthupalani, S; Taylor, NS; Mobley, M; Potter, A; Varro, A; Eibach, D; Suerbaum, S; Wang, TC; Fox, JG,期刊:Gastroenterology, 页码:210-+ , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Transgenic FVB/N insulin-gastrin (INS-GAS) mice have high circulating gastrin levels, and develop spontaneous atrophic gastritis and gastrointestinal intraepithelial neoplasia (GIN) with 80% prevalence...
- Anti-Tumor Necrosis Factor-alpha Antibodies Induce Regulatory Macrophages in an Fc Region-Dependent Manner
[作者:Vos, ACW; Wildenberg, ME; Duijvestein, M; Verhaar, AP; van den Brink, GR; Hommes, DW,期刊:Gastroenterology, 页码:221-+ , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Anti-tumor necrosis factor (TNF)alpha antibodies are effective in treating patients with Crohn's disease whereas soluble TNF alpha receptors have not shown clinical efficacy; the mechanism that underli...
- Analysis of Administrative Data Finds Endoscopist Quality Measures Associated With Postcolonoscopy Colorectal Cancer
[作者:Baxter, NN; Sutradhar, R; Forbes, SS; Paszat, LF; Saskin, R; Rabeneck, L,期刊:Gastroenterology, 页码:65-72 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Most quality indicators for colonoscopy measure processes; little is known about their relationship to patient outcomes. We investigated whether characteristics of endoscopists, determined from adminis...
- The PREMM1,2,6 Model Predicts Risk of MLH1, MSH2, and MSH6 Germline Mutations Based on Cancer History
[作者:Kastrinos, F; Steyerberg, EW; Mercado, R; Balmana, J; Holter, S; Gallinger, S; Siegmund, KD; Church, JM; Jenkins, MA; Lindor, NM; Thibodeau, SN; Burbidge, LA; Wenstrup, RJ; Syngal, S,期刊:Gastroenterology, 页码:73-+ , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: We developed and validated a model to estimate the risks of mutations in the mismatch repair (MMR) genes MLH1, MSH2, and MSH6 based on personal and family history of cancer. METHODS: Data were analyzed...
- TGF-beta(2) Suppresses Macrophage Cytokine Production and Mucosal Inflammatory Responses in the Developing Intestine
[作者:Maheshwari, A; Kelly, DR; Nicola, T; Ambalavanan, N; Jain, SK; Murphy-Ullrich, J; Athar, M; Shimamura, M; Bhandari, V; Aprahamian, C; Dimmitt, RA; Serra, R; Ohls, RK,期刊:Gastroenterology, 页码:242-253 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: Premature neonates are predisposed to necrotizing enterocolitis (NEC), an idiopathic, inflammatory bowel necrosis. We investigated whether NEC occurs in the preterm intestine due to incomplete noninfla...
- Mechanical Properties of the Esophagus in Eosinophilic Esophagitis
[作者:Kwiatek, MA; Hirano, I; Kahrilas, PJ; Rothe, J; Luger, D; Pandolfino, JE,期刊:Gastroenterology, 页码:82-90 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: This study aimed to analyze the mechanical properties of the esophagus in eosinophilic esophagitis (EoE) using the functional luminal imaging probe (EndoFLIP; Crospon Medical Devices, Galway, Ireland)....
- Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome
[作者:Tillisch, K; Mayer, EA; Labus, JS,期刊:Gastroenterology, 页码:91-100 , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND AND AIMS: The responsiveness of the central nervous system is altered in patients with irritable bowel syndrome (IBS). However, because of variations in experimental paradigms, analytic techniques, and reporti...
- Colitis and Intestinal Inflammation in IL10(-/-) Mice Results From IL-13R alpha 2-Mediated Attenuation of IL-13 Activity
[作者:Wilson, MS; Ramalingam, TR; Rivollier, A; Shenderov, K; Mentink-Kane, MM; Madala, SK; Cheever, AW; Artis, D; Kelsall, BL; Wynn, TA,期刊:Gastroenterology, 页码:254-+ , 文章类型: Article,,卷期:2011年140-1]
- BACKGROUND & AIMS: The cytokine interleukin (IL)-10 is required to maintain immune homeostasis in the gastrointestinal tract. IL-10 null mice spontaneously develop colitis or are more susceptible to induction of colitis ...
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