- A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes
[作者：Willing, BP; Dicksved, J; Halfvarson, J; Andersson, AF; Lucio, M; Zheng, Z; Jarnerot, G; Tysk, C; Jansson, JK; Engstrand, L,期刊：Gastroenterology, 页码：1844-U105 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: The composition of the gastrointestinal microbiota is thought to have an important role in the etiology of inflammatory bowel diseases (IBDs) such as Crohn's disease (CD) and ulcerative colitis (UC). I...
- Hypomethylation of the IGF2 DMR in Colorectal Tumors, Detected by Bisulfite Pyrosequencing, Is Associated With Poor Prognosis
[作者：Baba, Y; Nosho, K; Shima, K; Huttenhower, C; Tanaka, N; Hazra, A; Giovannucci, EL; Fuchs, CS; Ogino, S,期刊：Gastroenterology, 页码：1855-1864 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: The insulin-like growth factor 2 (IGF2) gene is normally imprinted. Constitutive loss of imprinting (LOI) of IGF2 has been associated with increased risks of colon cancer and adenoma, indicating its ro...
- Increased Expression of iASPP, Regulated by Hepatitis B Virus X Protein-Mediated NF-kappa B Activation, in Hepatocellular Carcinoma
[作者：Lu, B; Guo, HZ; Zhao, JA; Wang, C; Wu, GB; Pang, MS; Tong, X; Bu, FF; Liang, AM; Hou, S; Fan, XY; Dai, JX; Wang, H; Guo, YJ,期刊：Gastroenterology, 页码：2183-U525 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: iASPP is an inhibitory member of the ankyrin-repeat-, SH3-domain- and proline-rich-region-containing protein (ASPP) family; iASPP expression is up-regulated in different human tumor types. We explored ...
- T-Cell Immunoglobulin Mucin-3 Determines Severity of Liver Ischemia/Reperfusion Injury in Mice in a TLR4-Dependent Manner
[作者：Uchida, Y; Ke, BB; Freitas, MCS; Yagita, H; Akiba, H; Busuttil, RW; Najafian, N; Kupiec-Weglinski, JW,期刊：Gastroenterology, 页码：2195-2206 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: T-cell immunoglobulin mucin (TIM) genes are expressed by T cells and regulate host immunity and tolerance. CD4(+) T cells mediate innate immunity-dominated liver ischemia-reperfusion injury (IRI) by un...
- Linaclotide Improves Abdominal Pain and Bowel Habits in a Phase IIb Study of Patients With Irritable Bowel Syndrome With Constipation
[作者：Johnston, JM; Kurtz, CB; MacDougall, JE; Lavins, BJ; Currie, MG; Fitch, DA; O'Dea, C; Baird, M; Lembo, AJ,期刊：Gastroenterology, 页码：1877-U139 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Linaclotide, a minimally absorbed, 14-amino acid peptide agonist of guanylate cyclase-C, has shown benefit in a proof-of-concept study for the treatment of patients with irritable bowel syndrome (IBS) ...
- Proton Pump Inhibitor Therapy Improves Symptoms in Postnasal Drainage
[作者：Vaezi, MF; Hagaman, DD; Slaughter, JC; Tanner, SB; Duncavage, JA; Allocco, CT; Sparkman, C; Clement, LE; Wasden, CM; Wirth, D; Goutte, M; McCafferty, BA; Lanza, DC,期刊：Gastroenterology, 页码：1887-U147 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Gastroesophageal reflux is common among patients with postnasal drainage. We investigated whether proton pump inhibitor therapy improved symptoms in patients with postnasal drainage without sinusitis o...
- Abdominal Visceral Adipose Tissue Volume Is Associated With Increased Risk of Erosive Esophagitis in Men and Women
[作者：Nam, SY; Choi, IJ; Ryu, KH; Park, BJ; Kim, HB; Nam, BH,期刊：Gastroenterology, 页码：1902-U169 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Data on the association between erosive esophagitis and obesity are inconsistent because of variations in study populations and methods used to determine obesity. METHODS: Participants in a prospective...
- An Association Between Dietary Arachidonic Acid, Measured in Adipose Tissue, and Ulcerative Colitis
[作者：de Silva, PSA; Olsen, A; Christensen, J; Schmidt, EB; Overvaad, K; Tjonneland, A; Hart, AR,期刊：Gastroenterology, 页码：1912-1917 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Dietary arachidonic acid, an n-6 polyunsaturated fatty acid (n-6 PUFA), might be involved in the etiology of ulcerative colitis (UC). We performed a prospective cohort study to determine whether high l...
- Interval Fecal Immunochemical Testing in a Colonoscopic Surveillance Program Speeds Detection of Colorectal Neoplasia
[作者：Lane, JM; Chow, E; Young, GP; Good, N; Smith, A; Bull, J; Sandford, J; Morcom, J; Bampton, PA; Cole, SR,期刊：Gastroenterology, 页码：1918-1926 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Rapidly progressing or missed lesions can reduce the effectiveness of colonoscopy-based colorectal cancer surveillance programs. We investigated whether giving fecal immunochemical tests (FITs) for hem...
- Frequent Gastrointestinal Polyps and Colorectal Adenocarcinomas in a Prospective Series of PTEN Mutation Carriers
[作者：Heald, B; Mester, J; Rybicki, L; Orloff, MS; Burke, CA; Eng, C,期刊：Gastroenterology, 页码：1927-1933 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Germline phosphatase and tensin homolog (PTEN) mutations cause Cowden syndrome (CS), associated with breast and thyroid cancers. Case reports found 35%- 85% of CS patients had gastrointestinal (GI) ham...
- Long-term Therapy With Tenofovir Is Effective for Patients Co-Infected With Human Immunodeficiency Virus and Hepatitis B Virus
[作者：de Vries-Sluijs, TEMS; Reijnders, JGP; Hansen, BE; Zaaijer, HL; Prins, JM; Pas, SD; Schutten, M; Hoepelman, AIM; Richter, C; Mulder, JW; de Man, RA; Janssen, HLA; van der Ende, ME,期刊：Gastroenterology, 页码：1934-1941 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: We investigated the long-term efficacy and renal safety of tenofovir disoproxil fumarate (TDF), administered to patients co-infected with human immunodeficiency virus and hepatitis B virus (HBV) as par...
- Loci From a Genome-Wide Analysis of Bilirubin Levels Are Associated With Gallstone Risk and Composition
[作者：Buch, S; Schafmayer, C; Volzke, H; Seeger, M; Miquel, JF; Sookoian, SC; Egberts, JH; Arlt, A; Pirola, CJ; Lerch, MM; John, U; Franke, A; von Kampen, O; Brosch, M; Nothnagel, M; Kratzer, W; Boehm, BO; Broring, DC; Schreiber, S; Krawczak, M; Hampe, J,期刊：Gastroenterology, 页码：1942-U211 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Genome-wide association studies have mapped loci that are associated with serum levels of bilirubin. Bilirubin is a major component of gallstones so we investigated whether these variants predict galls...
- Prognostic Value of Endoscopy in Children With Biliary Atresia at Risk for Early Development of Varices and Bleeding
[作者：Duche, M; Ducot, B; Tournay, E; Fabre, M; Cohen, J; Jacquemin, E; Bernard, O,期刊：Gastroenterology, 页码：1952-1960 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Biliary atresia is the most common cause of childhood cirrhosis. We investigated prospectively the development of portal hypertension in 139 children with biliary atresia, the risk of gastrointestinal ...
- Splanchnic Balance of Free Fatty Acids, Endocannabinoids, and Lipids in Subjects With Nonalcoholic Fatty Liver Disease
[作者：Westerbacka, J; Kotronen, A; Fielding, BA; Wahren, J; Hodson, L; Perttila, J; Seppanen-Laakso, T; Suortti, T; Arola, J; Hultcrantz, R; Castillo, S; Olkkonen, VM; Frayn, KN; Oresic, M; Yki-Jarvinen, H,期刊：Gastroenterology, 页码：1961-U232 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Animal studies suggest that endocannabinoids could contribute to the development of nonalcoholic fatty liver disease (NAFLD). In addition, NAFLD has been shown to be associated with multiple changes in...
- Induction Pegylated Interferon Alfa-2a and High Dose Ribavirin Do Not Increase SVR in Heavy Patients With HCV Genotype 1 and High Viral Loads
[作者：Reddy, KR; Shiffman, ML; Rodriguez-Torres, M; Cheinquer, H; Abdurakhmanov, D; Bakulin, I; Morozov, V; Silva, GF; Geyvandova, N; Stanciu, C; Rabbia, M; McKenna, M; Thommes, JA; Harrison, SA,期刊：Gastroenterology, 页码：1972-1983 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: Patients infected with hepatitis C virus (HCV) genotype 1, body weight >= 85 kg, and high baseline viral load respond poorly to standard doses of pegylated interferon (peginterferon) and ribavirin. We ...
- Up-regulation of Activation-Induced Cytidine Deaminase Causes Genetic Aberrations at the CDKN2b-CDKN2a in Gastric Cancer
[作者：Matsumoto, Y; Marusawa, H; Kinoshita, K; Niwa, Y; Sakai, Y; Chiba, T,期刊：Gastroenterology, 页码：1984-1994 , 文章类型： Article，,卷期：2010年139-6]
- BACKGROUND & AIMS: The DNA/RNA editing enzyme activation-induced cytidine deaminase (AID) is mutagenic and has been implicated in human tumorigenesis. Helicobacter pylori infection of gastric epithelial cells leads to ab...
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