- Arginine methylation mediated by the Arabidopsis homolog of PRMT5 is essential for proper pre-mRNA splicing
[作者:Deng, XA; Gu, LF; Liu, CY; Lu, TC; Lu, FL; Lu, ZK; Cui, P; Pei, YX; Wang, BC; Hu, SN; Cao, XF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19114-19119 , 文章类型: Article,,卷期:2010年107-44]
- Protein arginine methylation, one of the most abundant and important posttranslational modifications, is involved in a multitude of biological processes in eukaryotes, such as transcriptional regulation and RNA processin...
- Adaptation and extinction in experimentally fragmented landscapes
[作者:Fakheran, S; Paul-Victor, C; Heichinger, C; Schmid, B; Grossniklaus, U; Turnbull, LA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19120-19125 , 文章类型: Article,,卷期:2010年107-44]
- Competition and disturbance are potent ecological forces that shape evolutionary trajectories. These forces typically work in opposition: when disturbance is infrequent, densities are high and competition is intense. In ...
- Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype
[作者:Xu, XS; Yang, H; Lin, YF; Li, XA; Cape, A; Ressler, KJ; Li, SH; Li, XJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19126-19131 , 文章类型: Article,,卷期:2010年107-44]
- Recent studies suggest that the human Abelson helper integration site-1 (AHI1) gene on chromosome 6 is associated with susceptibility to schizophrenia and autism, two common neuropsychological disorders with depression s...
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes (vol 107, pg 15449, 2010)
[作者:Taube, JH; Herschkowitz, JI; Komurov, K; Zhou, AY; Gupta, S; Yang, J; Hartwell, K; Onder, TT; Gupta, PB; Evans, KW; Hollier, BG; Ram, PT; Lander, ES; Rosen, JM; Weinberg, RA; Mani, SA,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19132-19132 , 文章类型: Correction,,卷期:2010年107-44]
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- Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors (vol 107, pg 15874, 2010)
[作者:Lo, SC; Pripuzova, N; Li, BJ; Komaroff, AL; Hung, GC; Wang, R; Alter, HJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:19132-19132 , 文章类型: Correction,,卷期:2010年107-44]
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- B-cell activating factor and v-Myc myelocytomatosis viral oncogene homolog (c-Myc) influence progression of chronic lymphocytic leukemia
[作者:Zhang, WZ; Kater, AP; Widhopf, GF; Chuang, HY; Enzler, T; James, DF; Poustovoitov, M; Tseng, PH; Janz, S; Hoh, C; Herschman, H; Karin, M; Kipps, TJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18956-18960 , 文章类型: Article,,卷期:2010年107-44]
- Mice bearing a v-Myc myelocytomatosis viral oncogene homolog (c-Myc) transgene controlled by an Ig-alpha heavy-chain enhancer (iMyc(C alpha) mice) rarely develop lymphomas but instead have increased rates of memory B-cel...
- EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda
[作者:Aggarwal, S; Negi, S; Jha, P; Singh, PK; Stobdan, T; Pasha, MAQ; Ghosh, S; Agrawal, A; Prasher, B; Mukerji, M,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18961-18966 , 文章类型: Article,,卷期:2010年107-44]
- It is being realized that identification of subgroups within normal controls corresponding to contrasting disease susceptibility is likely to lead to more effective predictive marker discovery. We have previously used th...
- Endothelial histamine H-1 receptor signaling reduces blood-brain barrier permeability and susceptibility to autoimmune encephalomyelitis
[作者:Lu, CM; Diehl, SA; Noubade, R; Ledoux, J; Nelson, MT; Spach, K; Zachary, JF; Blankenhorn, EP; Teuscher, C,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18967-18972 , 文章类型: Article,,卷期:2010年107-44]
- Disruption of the blood-brain barrier (BBB) underlies the development of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis. Environmental factors, such as Bordetella pertussis, are thought to sensiti...
- Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes
[作者:Wang, TT; Tan, GS; Hai, R; Pica, N; Ngai, L; Ekiert, DC; Wilson, IA; Garcia-Sastre, A; Moran, TM; Palese, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18979-18984 , 文章类型: Article,,卷期:2010年107-44]
- Current influenza virus vaccines protect mostly against homologous virus strains; thus, regular immunization with updated vaccine formulations is necessary to guard against the virus' hallmark remodeling of regions that ...
- An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation
[作者:Tan, MH; Kozdon, JB; Shen, XL; Shapiro, L; McAdams, HH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18985-18990 , 文章类型: Article,,卷期:2010年107-44]
- A cyclical control circuit composed of four master regulators drives the Caulobacter cell cycle. We report that SciP, a helix-turn-helix transcription factor, is an essential component of this circuit. SciP is cell cycle...
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