- Kinetics of fiber solidification
[作者:Mercader, C; Lucas, A; Derre, A; Zakri, C; Moisan, S; Maugey, M; Poulin, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18331-18335 , 文章类型: Article,,卷期:2010年107-43]
- Many synthetic or natural fibers are produced via the transformation of a liquid solution into a solid filament, which allows the wet processing of high molecular weight polymers, proteins, or inorganic particles. Synthe...
- Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration
[作者:Samara, C; Rohde, CB; Gilleland, CL; Norton, S; Haggarty, SJ; Yanik, MF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18342-18347 , 文章类型: Article,,卷期:2010年107-43]
- Discovery of molecular mechanisms and chemical compounds that enhance neuronal regeneration can lead to development of therapeutics to combat nervous system injuries and neurodegenerative diseases. By combining high-thro...
- Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms
[作者:Faust, TW; Chang, EH; Kowal, C; Berlin, R; Gazaryan, IG; Bertini, E; Zhang, J; Sanchez-Guerrero, J; Fragoso-Loyo, HE; Volpe, BT; Diamond, B; Huerta, PT,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18569-18574 , 文章类型: Article,,卷期:2010年107-43]
- Damaging interactions between antibodies and brain antigenic targets may be responsible for an expanding range of neurological disorders. In the case of systemic lupus erythematosus (SLE), patients generate autoantibodie...
- Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation
[作者:Choi, JM; Shin, JH; Sohn, MH; Harding, MJ; Park, JH; Tobiasova, Z; Kim, DY; Maher, SE; Chae, WJ; Park, SH; Lee, CG; Lee, SK; Bothwell, ALM,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18575-18580 , 文章类型: Article,,卷期:2010年107-43]
- Foxp3 is a key transcription factor for differentiation and function of regulatory T (Treg) cells that is critical for maintaining immunological self-tolerance. Therefore, increasing Treg function by Foxp3 transduction t...
- Persistence of climate changes due to a range of greenhouse gases
[作者:Solomon, S; Daniel, JS; Sanford, TJ; Murphy, DM; Plattner, GK; Knutti, R; Friedlingstein, P,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18354-18359 , 文章类型: Article,,卷期:2010年107-43]
- Emissions of a broad range of greenhouse gases of varying lifetimes contribute to global climate change. Carbon dioxide displays exceptional persistence that renders its warming nearly irreversible for more than 1,000 y....
- IL-33 is a crucial amplifier of innate rather than acquired immunity
[作者:Oboki, K; Ohno, T; Kajiwara, N; Arae, K; Morita, H; Ishii, A; Nambu, A; Abe, T; Kiyonari, H; Matsumoto, K; Sudo, K; Okumura, K; Saito, H; Nakae, S,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18581-18586 , 文章类型: Article,,卷期:2010年107-43]
- IL-33, a member of the IL-1-related cytokines, is considered to be a proallergic cytokine that is especially involved in Th2-type immune responses. Moreover, like IL-1 alpha, IL-33 has been suggested to act as an "alarmi...
- Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins
[作者:Coelho, V; Krysov, S; Ghaemmaghami, AM; Emara, M; Potter, KN; Johnson, P; Packham, G; Martinez-Pomares, L; Stevenson, FK,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18587-18592 , 文章类型: Article,,卷期:2010年107-43]
- Surface Ig (sIg) of follicular lymphoma (FL) is vital for tumor cell survival. We found previously that the Ig in FL is unusual, because the variable region genes carry sequence motifs for N-glycan addition. These are in...
- Biogeographic and evolutionary implications of a diverse paleobiota in amber from the early Eocene of India
[作者:Rust, J; Singh, H; Rana, RS; McCann, T; Singh, L; Anderson, K; Sarkar, N; Nascimbene, PC; Stebner, F; Thomas, JC; Kraemer, MS; Williams, CJ; Engel, MS; Sahni, A; Grimaldi, D,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18360-18365 , 文章类型: Article,,卷期:2010年107-43]
- For nearly 100 million years, the India subcontinent drifted from Gondwana until its collision with Asia some 50 Ma, during which time the landmass presumably evolved a highly endemic biota. Recent excavations of rich ou...
- Fluid dynamical niches of phytoplankton types
[作者:d'Ovidio, F; De Montec, S; Alvain, S; Dandonneau, Y; Levy, M,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18366-18370 , 文章类型: Article,,卷期:2010年107-43]
- The biogeochemical role of phytoplanktonic organisms strongly varies from one plankton type to another, and their relative abundance and distribution have fundamental consequences at the global and climatological scales....
- Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice
[作者:Nabekura, T; Shibuya, K; Takenaka, E; Kai, H; Shibata, K; Yamashita, Y; Harada, K; Tahara-Hanaoka, S; Honda, S; Shibuya, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18593-18598 , 文章类型: Article,,卷期:2010年107-43]
- Acute graft-versus-host disease (GVHD) is a life-threatening complication following bone marrow transplantation; however, no effective molecular-targeting therapy has been determined. Here, we show that mice that receive...
- Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules
[作者:Guillaume, B; Chapiro, J; Stroobant, V; Colau, D; Van Holle, B; Parvizi, G; Bousquet-Dubouch, MP; Theate, I; Parmentier, N; Van den Eynde, BJ,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:18599-18604 , 文章类型: Article,,卷期:2010年107-43]
- Most antigenic peptides presented by MHC class I molecules result from the degradation of intracellular proteins by the proteasome. In lymphoid tissues and cells exposed to IFN gamma, the standard proteasome is replaced ...
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