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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共42条记录   CD57 defines a functionally distinct population of mature NK cells in the human CD56(dim)CD16(+) NK-cell subset [作者：Lopez-Verges, S; Milush, JM; Pandey, S; York, VA; Arakawa-Hoyt, J; Pircher, H; Norris, PJ; Nixon, DF; Lanier, LL,期刊：Blood, 页码：3865-3874 , 文章类型： Article，,卷期：2010年116-19] Natural killer (NK) cells are innate immune lymphocytes that express a heterogeneous repertoire of germline-encoded receptors and undergo a distinct pattern of maturation. CD57 is a marker of terminal differentiation on ... Adoptive transfer of syngeneic T cells transduced with a chimeric antigen receptor that recognizes murine CD19 can eradicate lymphoma and normal B cells [作者：Kochenderfer, JN; Yu, ZY; Frasheri, D; Restifo, NP; Rosenberg, SA,期刊：Blood, 页码：3875-3886 , 文章类型： Article，,卷期：2010年116-19] Adoptive T-cell therapy with anti-CD19 chimeric antigen receptor (CAR)-expressing T cells is a new approach for treating advanced B-cell malignancies. To evaluate anti-CD19-CAR-transduced T cells in a murine model of ado... Interleukin-23 acts as antitumor agent on childhood B-acute lymphoblastic leukemia cells [作者：Cocco, C; Canale, S; Frasson, C; Di Carlo, E; Ognio, E; Ribatti, D; Prigione, I; Basso, G; Airoldi, I,期刊：Blood, 页码：3887-3898 , 文章类型： Article，,卷期：2010年116-19] Interleukin (IL)-23 is a proinflammatory cytokine belonging to the IL-12 superfamily. The antitumor activity of IL-23 is controversial, and it is unknown whether or not the cytokine can act directly on tumor cells. Th... An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas [作者：Pham, LV; Tamayo, AT; Li, CP; Bueso-Ramos, C; Ford, RJ,期刊：Blood, 页码：3899-3906 , 文章类型： Article，,卷期：2010年116-19] The nuclear factor of activated T cells (NFAT) family of transcription factors functions as integrators of multiple signaling pathways by binding to chromatin in combination with other transcription factors and coactivat... CD34(+) cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice [作者：Martelli, MP; Pettirossi, V; Thiede, C; Bonifacio, E; Mezzasoma, F; Cecchini, D; Pacini, R; Tabarrini, A; Ciurnelli, R; Gionfriddo, I; Manes, N; Rossi, R; Giunchi, L; Oelschlagel, U; Brunetti, L; Gemei, M; Delia, M; Specchia, G; Liso, A; Di Ianni, M; Di Raimondo, F; Falzetti, F; Del Vecchio, L; Martelli, MF; Falini, B,期刊：Blood, 页码：3907-3922 , 文章类型： Article，,卷期：2010年116-19] Acute myeloid leukemia (AML) with mutated NPM1 shows distinctive biologic and clinical features, including absent/ low CD34 expression, the significance of which remains unclear. Therefore, we analyzed CD34(+) cells from... Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value [作者：Smith, AE; Mohamedali, AM; Kulasekararaj, A; Lim, Z; Gaken, J; Lea, NC; Przychodzen, B; Mian, SA; Nasser, EE; Shooter, C; Westwood, NB; Strupp, C; Gattermann, N; Maciejewski, JP; Germing, U; Mufti, GJ,期刊：Blood, 页码：3923-3932 , 文章类型： Article，,卷期：2010年116-19] Mutations in the TET2 gene are frequent in myeloid disease, although their biologic and prognostic significance remains unclear. We analyzed 355 patients with myelodysplastic syndromes using "next-generation" sequencing ... Tissue transglutaminase contributes to the all-trans-retinoic acid-induced differentiation syndrome phenotype in the NB4 model of acute promyelocytic leukemia [作者：Csomos, K; Nemet, I; Fesus, L; Balajthy, Z,期刊：Blood, 页码：3933-3943 , 文章类型： Article，,卷期：2010年116-19] Treatment of acute promyelocytic leukemia (APL) with all-trans-retinoic acid (ATRA) results in terminal differentiation of leukemic cells toward neutrophil granulocytes. Administration of ATRA leads to massive changes in... Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants [作者：Balla, KM; Lugo-Villarino, G; Spitsbergen, JM; Stachura, DL; Hu, Y; Banuelos, K; Romo-Fewell, O; Aroian, RV; Traver, D,期刊：Blood, 页码：3944-3954 , 文章类型： Article，,卷期：2010年116-19] Eosinophils are granulocytic leukocytes implicated in numerous aspects of immunity and disease. The precise functions of eosinophils, however, remain enigmatic. Alternative models to study eosinophil biology may thus yie... An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation [作者：MacDonald, KPA; Palmer, JS; Cronau, S; Seppanen, E; Olver, S; Raffelt, NC; Kuns, R; Pettit, AR; Clouston, A; Wainwright, B; Branstetter, D; Smith, J; Paxton, RJ; Cerretti, DP; Bonham, L; Hill, GR; Hume, DA,期刊：Blood, 页码：3955-3963 , 文章类型： Article，,卷期：2010年116-19] The development of the mononuclear phagocyte system requires macrophage colony-stimulating factor (CSF-1) signaling through the CSF-1 receptor (CSF1R, CD115). We examined the effect of an antibody against CSF1R on macrop... Krox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone mass [作者：Gabet, Y; Baniwal, SK; Leclerc, N; Shi, YF; Kohn-Gabet, AE; Cogan, J; Dixon, A; Bachar, M; Guo, LX; Turman, JE; Frenkel, B,期刊：Blood, 页码：3964-3971 , 文章类型： Article，,卷期：2010年116-19] Krox20/EGR2, one of the 4 early growth response genes, is a highly conserved transcription factor implicated in hind-brain development, peripheral nerve myelination, tumor suppression, and monocyte/macrophage cell fate d...