- Structural determinants for the formation of sulfhemeprotein complexes
[作者:Roman-Morales, E; Pietri, R; Ramos-Santana, B; Vinogradov, SN; Lewis-Ballester, A; Lopez-Garriga, J,期刊:Biochemical and Biophysical Research Communications, 页码:489-492 , 文章类型: Article,,卷期:2010年400-4]
- Several hemoglobins were explored by UV-Vis and resonance Raman spectroscopy to define sulfheme complex formation. Evaluation of these proteins upon the reaction with H2O2 or O-2 in the presence of H2S suggest: (a) the f...
- Genetic tracing of the neural pathway for bitter taste in t2r5-WGA transgenic mice
[作者:Ohmoto, M; Maeda, N; Abe, K; Yoshihara, Y; Matsumoto, I,期刊:Biochemical and Biophysical Research Communications, 页码:734-738 , 文章类型: Article,,卷期:2010年400-4]
- To visualize the neural pathways originating from bitter taste receptor cells (TRCs), we generated transgenic mice expressing the transneuronal tracer wheat germ agglutinin (WGA) under the control of the mouse T2R5 gene ...
- AS1907417, a novel GPR119 agonist, as an insulinotropic and beta-cell preservative agent for the treatment of type 2 diabetes
[作者:Yoshida, S; Tanaka, H; Oshima, H; Yamazaki, T; Yonetoku, Y; Ohishi, T; Matsui, T; Shibasaki, M,期刊:Biochemical and Biophysical Research Communications, 页码:745-751 , 文章类型: Article,,卷期:2010年400-4]
- G-protein-coupled receptor (GPR) 119 is involved in glucose-stimulated insulin secretion (GSIS) and represents a promising target for the treatment of type 2 diabetes as it is highly expressed in pancreatic beta-cells. A...
- The cleavage of N-cadherin is essential for chondrocyte differentiation
[作者:Nakazora, S; Matsumine, A; Iino, T; Hasegawa, M; Kinoshita, A; Uemura, K; Niimi, R; Uchida, A; Sudo, A,期刊:Biochemical and Biophysical Research Communications, 页码:493-499 , 文章类型: Article,,卷期:2010年400-4]
- The aggregation of chondroprogenitor mesenchymal cells into precartilage condensation represents one of the earliest events in chondrogenesis. N-cadherin is a key cell adhesion molecule implicated in chondrogenic differe...
- Wnt5a/Ror2-induced upregulation of xPAPC requires xShcA
[作者:Feike, AC; Rachor, K; Gentzel, M; Schambony, A,期刊:Biochemical and Biophysical Research Communications, 页码:500-506 , 文章类型: Article,,卷期:2010年400-4]
- Ror receptor-tyrosine kinases act as Wnt-5a receptors in beta-catenin independent Wnt-signaling pathways. In Xenopus, expression of xPAPC is regulated by a Wnt-5a/Ror2 pathway, which resembles typical signaling cascades ...
- The role of the glycine triad in human glutathione synthetase
[作者:Dinescu, A; Brown, TR; Barelier, S; Cundari, TR; Anderson, ME,期刊:Biochemical and Biophysical Research Communications, 页码:511-516 , 文章类型: Article,,卷期:2010年400-4]
- Experimental kinetics and computational modeling of human glutathione synthetase (hGS) support the significant role of the G-loop glycine triad (G369, G370, G371) for activity of this ATP-grasp enzyme. Enzyme kinetic exp...
- Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus
[作者:Kim, SJ; Ha, BH; Kim, KH; Hong, SK; Shin, KJ; Suh, SW; Kim, EE,期刊:Biochemical and Biophysical Research Communications, 页码:517-522 , 文章类型: Article,,卷期:2010年400-4]
- Enoyl-[acyl carrier protein] reductase (ENR) is an essential enzyme in type II fatty-acid synthesis that catalyzes the last step in each elongation cycle. Thus far FabI, FabL and FabK have been reported to carry out the ...
- Mel-18, a mammalian Polycomb gene, regulates angiogenic gene expression of endothelial cells
[作者:Jung, JH; Choi, HJ; Maeng, YS; Choi, JY; Kim, M; Kwon, JY; Park, YW; Kim, YM; Hwang, D; Kwon, YG,期刊:Biochemical and Biophysical Research Communications, 页码:523-530 , 文章类型: Article,,卷期:2010年400-4]
- Mel-18 is a mammalian homolog of Polycomb group (PcG) genes. Microarray analysis revealed that Mel-18 expression was induced during endothelial progenitor cell (EPC) differentiation and correlates with the expression of ...
- Amyloid formation and disaggregation of alpha-synuclein and its tandem repeat (alpha-TR)
[作者:Bae, SY; Kim, S; Hwang, H; Kim, HK; Yoon, HC; Kim, JH; Lee, S; Kim, TD,期刊:Biochemical and Biophysical Research Communications, 页码:531-536 , 文章类型: Article,,卷期:2010年400-4]
- The aggregation of alpha-synuclein is clearly related to the pathogenesis of Parkinson's disease. Therefore, detailed understanding of the mechanism of fibril formation is highly valuable for the development of clinical ...
- Arginine 469 is a pivotal residue for the Hsc70-GlcNAc-binding property
[作者:Guinez, C; Mir, AM; Martin, N; Leprince, D; Michalski, JC; Vergoten, G; Lefebvre, T,期刊:Biochemical and Biophysical Research Communications, 页码:537-542 , 文章类型: Article,,卷期:2010年400-4]
- The members of the 70 kDa-heat shock proteins (HSP70) family play numerous fundamental functions in the cell such as promoting the assembly of multimeric complexes or helping the correct folding of nascent proteins to ta...
- Cleavage by MALT1 induces cytosolic release of A20
[作者:Malinverni, C; Unterreiner, A; Staal, J; Demeyer, A; Galaup, M; Luyten, M; Beyaert, R; Bornancin, F,期刊:Biochemical and Biophysical Research Communications, 页码:543-547 , 文章类型: Article,,卷期:2010年400-4]
- The MALT1 paracaspase has arginine-directed proteolytic activity. A20 is a dual ubiquitin-editing enzyme involved in termination of NF-kappa B signaling. Upon T- or B-cell receptor engagement human (h) A20 is cleaved by ...
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