- Mitochondrial Enzyme Rhodanese Is Essential for 5 S Ribosomal RNA Import into Human Mitochondria
[作者：Smirnov, A; Comte, C; Mager-Heckel, AM; Addis, V; Krasheninnikov, IA; Martin, RP; Entelis, N; Tarassov, I,期刊：Journal of Biological Chemistry, 页码：30792-30803 , 文章类型： Article，,卷期：2010年285-40]
- 5 S rRNA is an essential component of ribosomes. In eukaryotic cells, it is distinguished by particularly complex intracellular traffic, including nuclear export and re-import. The finding that in mammalian cells 5 S rRN...
- Regulation of Chromatin Assembly/Disassembly by Rtt109p, a Histone H3 Lys(56)-specific Acetyltransferase, in Vivo
[作者：Durairaj, G; Chaurasia, P; Lahudkar, S; Malik, S; Shukla, A; Bhaumik, SR,期刊：Journal of Biological Chemistry, 页码：30472-30479 , 文章类型： Article，,卷期：2010年285-40]
- Rtt109p, a histone acetyltransferase, associates with active genes and acetylates lysine 56 on histone H3 in Saccharomyces cerevisiae. However, the functional role of Rtt109p or H3 Lys(56) acetylation in chromatin assemb...
- The Reciprocal Regulation of gamma-Synuclein and IGF-I Receptor Expression Creates a Circuit That Modulates IGF-I Signaling
[作者：Li, MJ; Yin, YC; Hua, H; Sun, XM; Luo, T; Wang, JA; Jiang, YF,期刊：Journal of Biological Chemistry, 页码：30480-30488 , 文章类型： Article，,卷期：2010年285-40]
- Insulin-like growth factor (IGF) system plays important roles in carcinogenesis and maintenance of the malignant phenotype. Signaling through the IGF-I receptor (IGF-IR) has been shown to stimulate the growth and motilit...
- ZFP423 Coordinates Notch and Bone Morphogenetic Protein Signaling, Selectively Up-regulating Hes5 Gene Expression
[作者：Masserdotti, G; Badaloni, A; Green, YS; Croci, L; Barili, V; Bergamini, G; Vetter, ML; Consalez, GG,期刊：Journal of Biological Chemistry, 页码：30814-30824 , 文章类型： Article，,卷期：2010年285-40]
- Zinc finger protein 423 encodes a 30 Zn-finger transcription factor involved in cerebellar and olfactory development. ZFP423 is a known interactor of SMAD1-SMAD4 and of Collier/Olf-1/EBF proteins, and acts as a modifier ...
- Substitution of 5-HT1A Receptor Signaling by a Light-activated G Protein-coupled Receptor
[作者：Oh, E; Maejima, T; Liu, C; Deneris, E; Herlitze, S,期刊：Journal of Biological Chemistry, 页码：30825-30836 , 文章类型： Article，,卷期：2010年285-40]
- Understanding serotonergic (5-HT) signaling is critical for understanding human physiology, behavior, and neuropsychiatric disease. 5-HT mediates its actions via ionotropic and metabotropic 5-HT receptors. The 5-HT1A rec...
- Characterization of the Prion Protein in Human Urine
[作者：Dagdanova, A; Ilchenko, S; Notari, S; Yang, QW; Obrenovich, ME; Hatcher, K; McAnulty, P; Huang, LQ; Zou, WQ; Kong, QZ; Gambetti, P; Chen, SG,期刊：Journal of Biological Chemistry, 页码：30489-30495 , 文章类型： Article，,卷期：2010年285-40]
- The presence of the prion protein (PrP) in normal human urine is controversial and currently inconclusive. This issue has taken a special relevance because prion infectivity has been demonstrated in urine of animals carr...
- Transcriptional Regulation of an Axonemal Central Apparatus Gene, Sperm-associated Antigen 6, by a SRY-related High Mobility Group Transcription Factor, S-SOX5
[作者：Kiselak, EA; Shen, XN; Song, JM; Gude, DR; Wang, JN; Brody, SL; Strauss, JF; Zhang, ZB,期刊：Journal of Biological Chemistry, 页码：30496-30505 , 文章类型： Article，,卷期：2010年285-40]
- SOX5 is a transcription factor with homology to the high mobility group box region of the testis-determining factor, SRY. Both the mouse and human SOX5 genes encode a 48-kDa SOX5 protein (S-SOX5) that is only present in ...
- The Biological Effects of C/EBP alpha in K562 Cells Depend on the Potency of the N-terminal Regulatory Region, Not on Specificity of the DNA Binding Domain
[作者：Ferrari-Amorotti, G; Mariani, SA; Novi, C; Cattelani, S; Pecorari, L; Corradini, F; Soliera, AR; Manzotti, G; Fragliasso, V; Zhang, Y; Martinez, RV; Lam, EWF; Guerzoni, C; Calabretta, B,期刊：Journal of Biological Chemistry, 页码：30837-30850 , 文章类型： Article，,卷期：2010年285-40]
- The transcription factor C/EBP alpha is more potent than C/EBP beta in inducing granulocitic differentiation and inhibiting BCR/ABL-expressing cells. We took a "domain swapping" approach to assess biological effects, mod...
- Metabolomic Profiling Reveals Biochemical Pathways and Biomarkers Associated with Pathogenesis in Cystic Fibrosis Cells
[作者：Wetmore, DR; Joseloff, E; Pilewski, J; Lee, DP; Lawton, KA; Mitchell, MW; Milburn, MV; Ryals, JA; Guo, LN,期刊：Journal of Biological Chemistry, 页码：30516-30522 , 文章类型： Article，,卷期：2010年285-40]
- Cystic fibrosis (CF) is a life-shortening disease caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. To gain an understanding of the epithelial dysfunction associated with CF mut...
- Hrs Controls Sorting of the Epithelial Na+ Channel between Endosomal Degradation and Recycling Pathways
[作者：Zhou, RF; Kabra, R; Olson, DR; Piper, RC; Snyder, PM,期刊：Journal of Biological Chemistry, 页码：30523-30530 , 文章类型： Article，,卷期：2010年285-40]
- Epithelial Na+ absorption is regulated by Nedd4-2, an E3 ubiquitin ligase that reduces expression of the epithelial Na+ channel (ENaC) at the cell surface. Defects in this regulation cause Liddle syndrome, an inherited f...
- Phosphorylation of Tau at Thr(212), Thr(231), and Ser(262) Combined Causes Neurodegeneration
[作者：Alonso, AD; Di Clerico, J; Li, B; Corbo, CP; Alaniz, ME; Grundke-Iqbal, I; Iqbal, K,期刊：Journal of Biological Chemistry, 页码：30851-30860 , 文章类型： Article，,卷期：2010年285-40]
- Abnormal hyperphosphorylation of the microtubule-associated protein Tau is a hallmark of Alzheimer disease and related diseases called tauopathies. As yet, the exact mechanism by which this pathology causes neurodegenera...
- Partial Agonist and Antagonist Activities of a Mutant Scorpion beta-Toxin on Sodium Channels
[作者：Karbat, I; Ilan, N; Zhang, JZ; Cohen, L; Kahn, R; Benveniste, M; Scheuer, T; Catterall, WA; Gordon, D; Gurevitz, M,期刊：Journal of Biological Chemistry, 页码：30531-30538 , 文章类型： Article，,卷期：2010年285-40]
- Scorpion beta-toxin 4 from Centruroides suffusus suffusus (Css4) enhances the activation of voltage-gated sodium channels through a voltage sensor trapping mechanism by binding the activated state of the voltage sensor i...
- An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-kappa B-inducing Kinase via Lys(63)-linked Ubiquitination
[作者：Jin, XJ; Jin, HR; Jung, HS; Lee, SJ; Lee, JH; Lee, JJ,期刊：Journal of Biological Chemistry, 页码：30539-30547 , 文章类型： Article，,卷期：2010年285-40]
- The NF-kappa B transcription factors control many physiological processes, including inflammation, immunity, and apoptosis. Its activity contributes to the development of various cell malignancies. NF-kappa B-inducing ki...
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