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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共54条记录   PrPC, the Cellular Isoform of the Human Prion Protein, Is a Novel Biomarker of HIV-Associated Neurocognitive Impairment and Mediates Neuroinflammation [作者：Roberts, TK; Eugenin, EA; Morgello, S; Clements, JE; Zink, MC; Berman, JW,期刊：American Journal of Pathology, 页码：1848-1860 , 文章类型： Article，,卷期：2010年177-4] Of the 33 million people infected with the human immunodeficiency virus (HIV) worldwide, 40-60% of individuals will eventually develop neurocognitive sequelae that can be attributed to the presence of HIV-1 in the centra... TLR2-Mediated Expansion of MDSCs Is Dependent on the Source of Tumor Exosomes [作者：Xiang, XY; Liu, YL; Zhuang, XY; Zhang, SQ; Michalek, S; Taylor, DD; Grizzle, W; Zhang, HG,期刊：American Journal of Pathology, 页码：1606-1610 , 文章类型： Article，,卷期：2010年177-4] Exosomes released from tumor cells having been shown to induce interleukin-6 release from myeloid-derived suppressor cells in a Toll-like receptor 2/Stat3-dependent manner. In this study, we show that exosomes released f... BRAF Mutation Is Rare in Advanced-Stage Low-Grade Ovarian Serous Carcinomas [作者：Wong, KK; Tsang, YTM; Deavers, MT; Mok, SC; Zu, ZF; Sun, C; Malpica, A; Wolf, JK; Lu, KH; Gershenson, DM,期刊：American Journal of Pathology, 页码：1611-1617 , 文章类型： Article，,卷期：2010年177-4] Low-grade ovarian serous carcinomas are believed to arise via an adenoma-serous borderline tumor-serous carcinoma sequence. In this study, we found that advanced-stage, low-grade ovarian serous carcinomas both with and w... Assessing Pulmonary Pathology by Detailed Examination of Respiratory Function [作者：Vaickus, LJ; Bouchard, J; Kim, J; Natarajan, S; Remick, DG,期刊：American Journal of Pathology, 页码：1861-1869 , 文章类型： Article，,卷期：2010年177-4] Pulmonary inflammation causes multiple alterations within the lung, including mucus production, recruitment of inflammatory cells, and airway hyperreactivity (AHR). Measurement of AHR by direct, invasive means (eg, mecha... Role of Ocular Complement Factor H in a Murine Model of Choroidal Neovascularization [作者：Lyzogubov, VV; Tytarenko, RG; Jha, P; Liu, JA; Bora, NS; Bora, PS,期刊：American Journal of Pathology, 页码：1870-1880 , 文章类型： Article，,卷期：2010年177-4] The objective of this study was to explore the relationship between local (ie, ocular) complement factor H (CFH) and choroidal neovascularization (CNV) associated with wet age-related macular degeneration (AMD), a leadin... FTY720 Regulates Bone Marrow Egress of Eosinophils and Modulates Late-Phase Skin Reaction in Mice [作者：Sugita, K; Kabashima, K; Sakabe, J; Yoshiki, R; Tanizaki, H; Tokura, Y,期刊：American Journal of Pathology, 页码：1881-1887 , 文章类型： Article，,卷期：2010年177-4] Eosinophilia in the blood and skin is frequently observed in patients with certain inflammatory skin diseases, such as atopic dermatitis. However, the mechanism underlying eosinophil circulation and the role of eosinophi... alpha B-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells [作者：Goplen, D; Bougnaud, S; Rajcevic, U; Boe, SO; Skaftnesmo, KO; Voges, J; Enger, PO; Wang, J; Tysnes, BB; Laerum, OD; Niclou, S; Bjerkvig, R,期刊：American Journal of Pathology, 页码：1618-1628 , 文章类型： Article，,卷期：2010年177-4] We have previously established two distinct glioma phenotypes by serial xenotransplantation of human glioblastoma (GBM) biopsies in nude rats. These tumors undergo a gradual transition from a highly invasive nonangiogeni... Phosphorylation of Focal Adhesion Kinase at Tyr397 in Gastric Carcinomas and its Clinical Significance [作者：Lai, IR; Chu, PY; Lin, HS; Liou, JY; Jan, YJ; Lee, JC; Shen, TL,期刊：American Journal of Pathology, 页码：1629-1637 , 文章类型： Article，,卷期：2010年177-4] Focal adhesion kinase (FAK) has been implicated in tumorigenesis in various cancers; however, it remains unclear how FAK participates in tumor malignancy in vivo. This study seeks to understand the role of FAK activation... Focal Adhesion Assembly in Myofibroblasts Fosters a Microenvironment that Promotes Tumor Growth [作者：Kang, NL; Yaqoob, U; Geng, ZM; Bloch, K; Liu, CS; Gomez, T; Billadeau, D; Shah, V,期刊：American Journal of Pathology, 页码：1888-1900 , 文章类型： Article，,卷期：2010年177-4] Cells within the tumor microenvironment influence tumor growth through multiple mechanisms. Pericytes such as hepatic stellate cells are an important cell within the tumor microenvironment; their transformation into high... Adaptive Calcified Matrix Response of Dental Pulp to Bacterial Invasion Is Associated with Establishment of a Network of Glial Fibrillary Acidic Protein(+)/Glutamine Synthetase(+) Cells [作者：Farahani, RM; Nguyen, KA; Simonian, M; Hunter, N,期刊：American Journal of Pathology, 页码：1901-1914 , 文章类型： Article，,卷期：2010年177-4] We report evidence for anatomical and functional changes of dental pulp in response to bacterial invasion through dentin that parallel responses to noxious stimuli reported in neural crest-derived sensory tissues. Sectio... Proteomic Analysis Identification of a Pattern of Shared Alterations in the Secretome of Dermal Fibroblasts from Systemic Sclerosis and Nephrogenic Systemic Fibrosis [作者：Del Galdo, F; Shaw, MA; Jimenez, SA,期刊：American Journal of Pathology, 页码：1638-1646 , 文章类型： Article，,卷期：2010年177-4] A proteomic analysis of the secretome of cultured dermal fibroblasts from patients with systemic sclerosis (SSc) and nephrogenic systemic fibrosis (NSF) was performed to identify proteins that reflect the fibrotic proces... PTEN, PIK3CA, p-AKT, and p-p70S6K Status Association with Trastuzumab Response and Survival in Patients with HER2-Positive Metastatic Breast Cancer [作者：Esteva, FJ; Guo, H; Zhang, SY; Santa-Maria, C; Stone, S; Lanchbury, JS; Sahin, AA; Hortobagyi, GN; Yu, DH,期刊：American Journal of Pathology, 页码：1647-1656 , 文章类型： Article，,卷期：2010年177-4] Phosphatase and tensin homolog (PTEN) is a key modulator of trastuzumab sensitivity in HER2-overexpressing breast cancer. Because PTEN opposes the downstream signaling of phosphoinositide 3-kinase (PI3K), we investigated... Epigenetic Repression of Matrix Metalloproteinases in Myofibroblastic Hepatic Stellate Cells through Histone Deacetylases 4 Implication in Tissue Fibrosis [作者：Qin, L; Han, YP,期刊：American Journal of Pathology, 页码：1915-1928 , 文章类型： Article，,卷期：2010年177-4] Matrix metalloproteinases (MMPs), which are highly expressed in acute injury, are progressively repressed or silenced in fibrotic liver, favoring extracellular matrix accumulation, while the underlying mechanism is large... Blockade of Endothelin-1 with a Novel Series of 1,3,6-Trisubstituted-2-Carboxy-Quinol-4-Ones Controls Infection-Associated Preterm Birth [作者：Olgun, NS; Patel, HJ; Stephani, R; Lengyel, I; Reznik, SE,期刊：American Journal of Pathology, 页码：1929-1935 , 文章类型： Article，,卷期：2010年177-4] Preterm birth (PTB) currently accounts for 13% of all births in the United States, with the leading cause of PTB being maternal infection. Endothelin-1, an extremely potent vasoconstrictor capable of increasing myometria... Adiponectin Lowers Glucose Production by Increasing SOGA [作者：Cowerd, RB; Asmar, MM; Alderman, JM; Alderman, EA; Garland, AL; Busby, WH; Bodnar, WM; Rusyn, I; Medoff, BD; Tisch, R; Mayer-Davis, E; Swenbere, JA; Zeisel, SH; Combs, TP,期刊：American Journal of Pathology, 页码：1936-1945 , 文章类型： Article，,卷期：2010年177-4] Adiponectin is a hormone that lowers glucose production by increasing liver insulin sensitivity. Insulin blocks the generation of biochemical intermediates for glucose production by inhibiting autophagy. However, autopha... Alveolar Macrophages Stimulate Enhanced Cytokine Production by Pulmonary CD4(+) T-Lymphocytes in an Exacerbation of Murine Chronic Asthma [作者：Herbert, C; Scott, MM; Scruton, KH; Keogh, RP; Yuan, KC; Hsu, K; Siegle, JS; Tedla, N; Foster, PS; Kumar, RK,期刊：American Journal of Pathology, 页码：1657-1664 , 文章类型： Article，,卷期：2010年177-4] The mechanisms underlying the exaggerated distal airway inflammation and hyperresponsiveness that characterize acute exacerbations of asthma are largely unknown. Using BALB/c mouse experimental models, we demonstrated a ...