- Epigenetic Reprogramming in Plant and Animal Development
[作者：Feng, SH; Jacobsen, SE; Reik, W,期刊：Science, 页码：622-627 , 文章类型： Review，,卷期：2010年330-6004]
- Epigenetic modifications of the genome are generally stable in somatic cells of multicellular organisms. In germ cells and early embryos, however, epigenetic reprogramming occurs on a genome-wide scale, which includes de...
- Paramutation's Properties and Puzzles
[作者：Chandler, VL,期刊：Science, 页码：628-629 , 文章类型： Editorial Material，,卷期：2010年330-6004]
- Paramutation refers to the process by which homologous DNA sequences communicate in trans to establish meiotically heritable expression states. Although mechanisms are unknown, current data are consistent with the hypoth...
- Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle
[作者：Feng, LA; Campbell, EB; Hsiung, YC; MacKinnon, R,期刊：Science, 页码：635-641 , 文章类型： Article，,卷期：2010年330-6004]
- CLC proteins transport chloride (Cl-) ions across cell membranes to control the electrical potential of muscle cells, transfer electrolytes across epithelia, and control the pH and electrolyte composition of intracellula...
- Diversity of Human Copy Number Variation and Multicopy Genes
[作者：Sudmant, PH; Kitzman, JO; Antonacci, F; Alkan, C; Malig, M; Tsalenko, A; Sampas, N; Bruhn, L; Shendure, J; Eichler, EE,期刊：Science, 页码：641-646 , 文章类型： Article，,卷期：2010年330-6004]
- Copy number variants affect both disease and normal phenotypic variation, but those lying within heavily duplicated, highly identical sequence have been difficult to assay. By analyzing short-read mapping depth for 159 h...
- Rate of Gas Phase Association of Hydroxyl Radical and Nitrogen Dioxide
[作者：Mollner, AK; Valluvadasan, S; Feng, L; Sprague, MK; Okumura, M; Milligan, DB; Bloss, WJ; Sander, SP; Martien, PT; Harley, RA; McCoy, AB; Carter, WPL,期刊：Science, 页码：646-649 , 文章类型： Article，,卷期：2010年330-6004]
- The reaction of OH and NO2 to form gaseous nitric acid (HONO2) is among the most influential in atmospheric chemistry. Despite its importance, the rate coefficient remains poorly determined under tropospheric conditions ...
- Direct Observation and Quantification of CO2 Binding Within an Amine-Functionalized Nanoporous Solid
[作者：Vaidhyanathan, R; Iremonger, SS; Shimizu, GKH; Boyd, PG; Alavi, S; Woo, TK,期刊：Science, 页码：650-653 , 文章类型： Article，,卷期：2010年330-6004]
- Understanding the molecular details of CO2-sorbent interactions is critical for the design of better carbon-capture systems. Here we report crystallographic resolution of CO2 molecules and their binding domains in a meta...
- The Occurrence and Mass Distribution of Close-in Super-Earths, Neptunes, and Jupiters
[作者：Howard, AW; Marcy, GW; Johnson, JA; Fischer, DA; Wright, JT; Isaacson, H; Valenti, JA; Anderson, J; Lin, DNC; Ida, S,期刊：Science, 页码：653-655 , 文章类型： Article，,卷期：2010年330-6004]
- The questions of how planets form and how common Earth-like planets are can be addressed by measuring the distribution of exoplanet masses and orbital periods. We report the occurrence rate of close-in planets (with orbi...
- Fitness Correlates of Heritable Variation in Antibody Responsiveness in a Wild Mammal
[作者：Graham, AL; Hayward, AD; Watt, KA; Pilkington, JG; Pemberton, JM; Nussey, DH,期刊：Science, 页码：662-665 , 文章类型： Article，,卷期：2010年330-6004]
- A functional immune system is important for survival in natural environments, where individuals are frequently exposed to parasites. Yet strong immune responses may have fitness costs if they deplete limited energetic re...
- Lineage Relationship Analysis of ROR gamma t(+) Innate Lymphoid Cells
[作者：Sawa, S; Cherrier, M; Lochner, M; Satoh-Takayama, N; Fehling, HJ; Langa, F; Di Santo, JP; Eberl, G,期刊：Science, 页码：665-669 , 文章类型： Article，,卷期：2010年330-6004]
- Lymphoid tissue-inducer (LTi) cells initiate the development of lymphoid tissues through the activation of local stromal cells in a process similar to inflammation. LTi cells express the nuclear hormone receptor ROR gamm...
- Filtering of Visual Information in the Tectum by an Identified Neural Circuit
[作者：Del Bene, F; Wyart, C; Robles, E; Tran, A; Looger, L; Scott, EK; Isacoff, EY; Baier, H,期刊：Science, 页码：669-673 , 文章类型： Article，,卷期：2010年330-6004]
- The optic tectum of zebrafish is involved in behavioral responses that require the detection of small objects. The superficial layers of the tectal neuropil receive input from retinal axons, while its deeper layers conve...
- Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for the 30S Subunit
[作者：Mulder, AM; Yoshioka, C; Beck, AH; Bunner, AE; Milligan, RA; Potter, CS; Carragher, B; Williamson, JR,期刊：Science, 页码：673-677 , 文章类型： Article，,卷期：2010年330-6004]
- Ribosomes are self-assembling macromolecular machines that translate DNA into proteins, and an understanding of ribosome biogenesis is central to cellular physiology. Previous studies on the Escherichia coli 30S subunit ...
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