- Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: Novel antitumor DNA monoalkylating agents
[作者:Soares, MIL; Brito, AF; Laranjo, M; Abrantes, AM; Botelho, MF; Paixao, JA; Beja, AM; Silva, MR; Melo, TMVDPE,期刊:European Journal of Medicinal Chemistry, 页码:4676-4681 , 文章类型: Article,,卷期:2010年45-10]
- New chiral 1H,3H-pyrrolo[1,2-c]thiazoles were synthesized and screened for their in vitro activity as anti-cancer agents in three human tumor cell lines, colorectal adenocarcinoma, melanoma and breast adenocarcinoma. (R)...
- E-2-[3-(3,4-Dichlorophenyl)-1-oxo-2-propenyl]-3-methylquinoxaline-1,4-dioxide: A lead antitubercular agent which alters mitochondrial respiration in rat liver
[作者:Das, U; Das, S; Bandy, B; Gorecki, DKJ; Dimmock, JR,期刊:European Journal of Medicinal Chemistry, 页码:4682-4686 , 文章类型: Article,,卷期:2010年45-10]
- A series of 2-(3-aryl-1-oxo-2-propenyl)-3-methylquinoxaline-1,4-dioxides 1a-1 and 2-acetyl-3-methyl-quinoxaline-1,4-dioxide 2 were evaluated against Mycobacterium tuberculosis H(37)Rv. With the exception of the 4-nitro a...
|