- Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats (vol 44, pg 3874, 2009)
[作者:Hoyem, S; Bruheim, S; Maelandsmo, G; Standal, M; Olberg, DE; Brudeli, B; Asberg, A; Klaveness, J; Rongved, P,期刊:European Journal of Medicinal Chemistry, 页码:4786-4786 , 文章类型: Correction,,卷期:2009年44-11]
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- Synthesis, spectroscopic characterization and antibacterial activity of new cobalt(II) complexes of unsymmetrical tetradentate (OSN2) Schiff base ligands
[作者:Saghatforoush, LA; Chalabian, F; Aminkhani, A; Karimnezhad, G; Ershad, S,期刊:European Journal of Medicinal Chemistry, 页码:4490-4495 , 文章类型: Article,,卷期:2009年44-11]
- Cobalt ion complexes with the Schiff bases, (4-X-2-{[2-(2-pyridine-2-yl-ethylsulfanyl)ethyliminolmethyl} phenol (X = methoxy (OMe), phenylazo (N2Ph), bromo (Br), nitro (NO2)),were synthesized and investigated by several ...
- Mapping the ribonucleolytic active site of bovine seminal ribonuclease. The binding of pyrimidinyl phosphonucleotide inhibitors
[作者:Dossi, K; Tsirkone, VG; Hayes, JM; Matousek, J; Pouckova, P; Soucek, J; Zadinova, M; Zographos, SE; Leonidas, DD,期刊:European Journal of Medicinal Chemistry, 页码:4496-4508 , 文章类型: Review,,卷期:2009年44-11]
- Bovine seminal ribonuclease (BS-RNase) is a 27 kDa homodimeric enzyme and a member of the pancreatic RNase A superfamily. It is the only RNase with a quaternary structure and it is a mixture of two dimeric forms. In the ...
- Synthesis, characterization and antibacterial activity of 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-pyrazol-4-yl]-5-(substituted-phenyl)- [1,3,4]oxadiazoles
[作者:Rai, NP; Narayanaswamy, VK; Shashikanth, S; Arunachalam, PN,期刊:European Journal of Medicinal Chemistry, 页码:4522-4527 , 文章类型: Article,,卷期:2009年44-11]
- In the present investigation a series of novel 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-IH-pyrazol-4yl]-5-(substituted-phenyl)-[1,3,4]oxadiazoles (4a-j) were synthesized by cyclization of substituted-benzoic acid N'-[1-...
- Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds
[作者:Aytac, SP; Tozkoparan, B; Kaynak, FB; Aktay, G; Goktas, O; Unuvar, S,期刊:European Journal of Medicinal Chemistry, 页码:4528-4538 , 文章类型: Article,,卷期:2009年44-11]
- In this study, a new class of 4-amino-3-substituted-1,2,4-triazole-5-thiones (1-4) and their corresponding condensed derivatives 3,6-disubstituted 7H-1,2,4-triazolo[3,4-bi-1,3,4-thiadiazines (1a-4c) were synthesized and ...
- Synthesis and antibacterial activity of some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines containing 1,2,4-triazinone moiety
[作者:Ali, TES,期刊:European Journal of Medicinal Chemistry, 页码:4539-4546 , 文章类型: Article,,卷期:2009年44-11]
- Some new thiadiaza/triazaphospholes, thiadiaza/triaza/tetrazaphosphinines and thiadiaza/tetrazaphosphepines fused with 6-methyl-1,2,4-triazin-5-one moiety were synthesized via reactions of alpha,beta-bifunctional compoun...
- New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage
[作者:Hamdy, NA; Gamal-Eldeen, AM,期刊:European Journal of Medicinal Chemistry, 页码:4547-4556 , 文章类型: Article,,卷期:2009年44-11]
- The reaction of 2-acetyl-5,6,7,8-tetrahydronaphthalene 1 with some aldehydes was conducted in the presence of ethyl cyanoacetate and ammonium acetate, yielded the cyanopyriclones 2a-c, which react with phosphorous pentas...
- Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives
[作者:Padmaja, A; Payani, T; Reddy, GD; Padmavathi, V,期刊:European Journal of Medicinal Chemistry, 页码:4557-4566 , 文章类型: Article,,卷期:2009年44-11]
- A newclass of heterocycles, substituted pyrazoles, isoxazoles, pyrimidines, thioxopyrimidines were prepared from Michael adducts, 2-(1,2-diaroyiethyl)malononitrile and 2-(1,2-diarylsulfonylethyl)malononitrile by cyclocon...
- Synthesis and anabolic/androgenic evaluation of novel 9 alpha-fluorosteroids
[作者:Reyes-Moreno, M; Ruiz-Garcia, JA; Ibarra-Reyes, Y; Fuente-Hernandez, A; Velez-Castro, H; Hernandez-Balmaseda, I; Martinez-Hormaza, I; Rodeiro-Guerra, I; Ramirez, JS; Reyes, SM; Montiel-Smith, S,期刊:European Journal of Medicinal Chemistry, 页码:4567-4571 , 文章类型: Article,,卷期:2009年44-11]
- 3 beta,11 beta-Dihydroxy-9 alpha-fluor-5 alpha-androstane-17-one (2), 3 beta-acetoxy-9 alpha-fluor-11 beta-hydroxy-5 alpha-androstane-17-one (3), 3 beta-acetoxy-9 alpha-fluor-11 beta,17 beta-dihydroxy-5 alpha-androstane ...
- Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines
[作者:Amin, KM; Hanna, MM; Abo-Youssef, HE; George, RF,期刊:European Journal of Medicinal Chemistry, 页码:4572-4584 , 文章类型: Article,,卷期:2009年44-11]
- Novel series of bicyclic pyrrolo[1,2-cipyrimidines 3a-g, 5, 6a, b, and 7a, b, tricyclic pyrimido[5,4-elpyrrolo[1,2-c]pyrimidines 8a-c, 9a-g, 13a-c, 17,18a, b, 19, 20a,b and 21 and tetracyclic condensed pyrimidines 14, 22...
- Synthesis, characterization, DNA binding properties and antioxidant activity of Ln(III) complexes with hesperetin-4-one-(benzoyl) hydrazone
[作者:Li, Y; Yang, ZY; Wang, MF,期刊:European Journal of Medicinal Chemistry, 页码:4585-4595 , 文章类型: Article,,卷期:2009年44-11]
- Novel Ln(III) complexes with hesperetin-4-one-(benzoyl) hydrazone (H4L) have been synthesized and characterized. Electronic absorption spectroscopy, fluorescence spectra, ethidium bromide displacement experiments, iodide...
- Antinociceptive properties of caffeic acid derivatives in mice
[作者:Buzzi, FD; Franzoi, CL; Antonini, G; Fracasso, M; Cechinel, V; Yunes, RA; Niero, R,期刊:European Journal of Medicinal Chemistry, 页码:4596-4602 , 文章类型: Article,,卷期:2009年44-11]
- Ten ester derivatives from caffeic acid were synthesized, and their antinociceptive properties are evaluated in mice. The most active compound, dodecyl ester derivative, exhibited potent and dose-related activity against...
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