- Coordinated Regulation of Dimethylarginine Dimethylaminohydrolase-1 and Cationic Amino Acid Transporter-1 by Farnesoid X Receptor in Mouse Liver and Kidney and Its Implication in the Control of Blood Levels of Asymmetric Dimethylarginine
[作者:Li, J; Wilson, A; Gao, X; Kuruba, R; Liu, YH; Poloyac, S; Pitt, B; Xie, W; Li, S,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:234-243 , 文章类型: Article,,卷期:2009年331-1]
- Asymmetric dimethylarginine (ADMA) is a potent endogenous inhibitor of endothelial nitric-oxide synthase (eNOS), and increased plasma concentrations of ADMA have been regarded as a risk factor for a number of cardiovascu...
- Mutant 5-Hydroxytryptamine(1A) Receptor D116A Is a Receptor Activated Solely by Synthetic Ligands with a Rich Pharmacology
[作者:Cussac, D; Palmier, C; Finana, F; De Vries, L; Tardif, S; Leger, C; Bernois, S; Heusler, P,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:222-233 , 文章类型: Article,,卷期:2009年331-1]
- Like other biogenic amine G protein-coupled receptors, mutation of the conserved aspartatic residue into alanine at position 116 (D116A(3.32)) in the 5-hydroxytryptamine (5-HT)(1A) receptor greatly affects 5-HT binding a...
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