- Agelastatin E, Agelastatin F, and Benzosceptrin C from the Marine Sponge Agelas dendromorpha
[作者:Tilvi, S; Moriou, C; Martin, MT; Gallard, JF; Sorres, J; Patel, K; Petek, S; Debitus, C; Ermolenko, L; Al-Mourabit, A,期刊:Journal of natural products, 页码:720-723 , 文章类型: Article,,卷期:2010年73-4]
- The study of the n-butanol extract of the New Caledonian sponge Agelas dendromorpha led to the isolation and identification of three new pyrrole-2-aminoimidazole (P-2-AI) alkaloids, named agelastatins E (3) and F (4) and...
- Malyngolide Dimer, a Bioactive Symmetric Cyclodepside from the Panamanian Marine Cyanobacterium Lyngbya majuscula
[作者:Gutierrez, M; Tidgewell, K; Capson, TL; Engene, N; Almanza, A; Schemies, J; Jung, M; Gerwick, WH,期刊:Journal of natural products, 页码:709-711 , 文章类型: Article,,卷期:2010年73-4]
- Fractionation of the extract of the marine cyanobacterium Lyngbya majuscula collected from Panama led to the isolation of malyngolide dimer (1). The planar structure of 1 was determined using ID and 2D NMR spectroscopy a...
- Homoisoflavonoids from the Fibrous Roots of Polygonatum odoratum with Glucose Uptake-Stimulatory Activity in 3T3-L1 Adipocytes
[作者:Zhang, H; Yang, F; Qi, J; Song, XC; Hu, ZF; Zhu, DN; Yu, BY,期刊:Journal of natural products, 页码:548-552 , 文章类型: Article,,卷期:2010年73-4]
- The EtOAc-soluble fraction of a 90% MeOH extract of the fibrous roots of Polygonatum ocloratum was found to potentiate insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes. Bioassay-guided fractionation ...
- Hopane-Type Triterpenes and Binaphthopyrones from the Scale Insect Pathogenic Fungus Aschersonia paraphysata BCC 11964
[作者:Isaka, M; Yangchum, A; Rachtawee, P; Komwijit, S; Lutthisungneon, A,期刊:Journal of natural products, 页码:688-692 , 文章类型: Article,,卷期:2010年73-4]
- Two new triterpenes, 17(21)-hopene-6 alpha,12 beta-diol (1) and 17(21)-hopen-12 beta-ol (2), the known 17(21)-hopen-6 alpha-ol (zeorinin, 3), and two new biarylic dihydronaphthopyrones, aschernaphthopyrones A (4) and B (...
- Rapid Structural Identification of Cytotoxic Bufadienolide Sulfates in Toad Venom from Bufo melanosticus by LC-DAD-MSn and LC-SPE-NMR
[作者:Gao, HM; Zehl, M; Kaehlig, H; Schneider, P; Stuppner, H; Banuls, LMY; Kiss, R; Kopp, B,期刊:Journal of natural products, 页码:603-608 , 文章类型: Article,,卷期:2010年73-4]
- Toad venom, namely, "Chansu" in China, has been widely used for the treatment of heart failure, sores, pains, and various cancers. Upon LC-MS analysis of the venom from Bufo melanosticus collected in Indonesia, new bufad...
- AMP-Activated Protein Kinase (AMPK) Activation by Benzofurans and Coumestans Isolated from Erythrina abyssinica
[作者:Nguyen, PH; Nguyen, TNA; Dao, TT; Kang, HW; Ndinteh, DT; Mbafor, JT; Oh, WK,期刊:Journal of natural products, 页码:598-602 , 文章类型: Article,,卷期:2010年73-4]
- AMP-activated protein kinase (AMPK) has been proposed as a therapeutic target for the treatment of metabolic syndrome including obesity and type-2 diabetes. The bioassay-guided fractionation of an EtOAc-soluble extract o...
- Cytotoxic Polyisoprenyl Benzophenonoids from Garcinia subelliptica
[作者:Zhang, LJ; Chiou, CT; Cheng, JJ; Huang, HC; Kuo, LMY; Liao, CC; Bastow, KF; Lee, KH; Kuo, YH,期刊:Journal of natural products, 页码:557-562 , 文章类型: Article,,卷期:2010年73-4]
- Six new polyisoprenyl benzophenonoids, (+/-)-garcinialiptone A (1, 2), garcinialiptone B (3), (-)-cycloxanthochymol (4), garcinialiptone C (5), and garcinialiptone D (6), along with three known compounds, xanthochymol (7...
- Humulane and Germacrane Sesquiterpenes from Ferula lycia
[作者:Alkhatib, R; Hennebelle, T; Joha, S; Roumy, V; Guzel, Y; Biabiany, M; Idziorek, T; Preudhomme, C; Quesnel, B; Sahpaz, S; Bailleul, F,期刊:Journal of natural products, 页码:780-783 , 文章类型: Article,,卷期:2010年73-4]
- Five new juniferol esters (1-5), along with six known humulane derivatives (6-11), were isolated from the roots of Ferula lycia, an endemic Turkish species. The fruits of the same species were also investigated and led t...
- Diarylheptanoid from Pleuranhodium racemigerum with in Vitro Prostaglandin E-2 Inhibitory and Cytotoxic Activity
[作者:Wohlmuth, H; Deseo, MA; Brushett, DJ; Thompson, DR; MacFarlane, G; Stevenson, LM; Leach, DN,期刊:Journal of natural products, 页码:743-746 , 文章类型: Article,,卷期:2010年73-4]
- Bioactivity-guided fractionation of an ethanolic extract of the rhizome of Pleuranthodium racemigerum, a tropical Zingiberaceae species from Northeastern Australia, resulted in the isolation and structural elucidation of...
- Antiangiogenic Metabolites from a Marine-Derived Fungus, Hypocrea vinosa
[作者:Ohkawa, Y; Miki, K; Suzuki, T; Nishio, K; Sugita, T; Kinoshita, K; Takahashi, K; Koyama, K,期刊:Journal of natural products, 页码:579-582 , 文章类型: Article,,卷期:2010年73-4]
- The aims of this study were to investigate the role of tyrosine kinase in intracellular signaling and to search for lead compounds with tyrosine kinase inhibitory activity from metabolites of marine-derived fungi. We ini...
- Differentiating and Apoptotic Dose-Dependent Effects in (-)-alpha-Bisabolol-Treated Human Endothelial Cells
[作者:Magnelli, L; Caldini, R; Schiavone, N; Suzuki, H; Chevanne, M,期刊:Journal of natural products, 页码:523-526 , 文章类型: Article,,卷期:2010年73-4]
- The effect on angiogenesis of (-)-alpha-bisabolol [(-)-6-methyl-2-(4-methyl-3-cyclohexen-1-y1)-5-hepten-2-ol] (1), a widely distributed plant sesquiterpene alcohol, was investigated for the first time. Human endothelial ...
- Semisynthesis of Natural Flavones Inhibiting Tubulin Polymerization, from Hesperidin
[作者:Lewin, G; Maciuk, A; Thoret, S; Aubert, G; Dubois, J; Cresteil, T,期刊:Journal of natural products, 页码:702-706 , 文章类型: Article,,卷期:2010年73-4]
- Semisynthesis of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone (1), a natural flavone that binds with high affinity to tubulin, was performed from hesperidin, the very abundant Citrus flavanone, by a five-step sequence. ...
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