- Aberrant Epithelial-Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia
[作者：Wang, DH; Clemons, NJ; Miyashita, T; Dupuy, AJ; Zhang, W; Szczepny, A; Schwartz, IMC; Wilburn, DL; Montgomery, EA; Wang, JS; Jenkins, NA; Copeland, NA; Harmon, JW; Phillips, WA; Watkins, DN,期刊：Gastroenterology, 页码：1810-U51 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: The molecular mechanism underlying epithelial metaplasia in Barrett's esophagus remains unknown. Recognizing that Hedgehog signaling is required for early esophageal development, we sought to determine...
- A Novel Gastrokine, Gkn3, Marks Gastric Atrophy and Shows Evidence of Adaptive Gene Loss in Humans
[作者：Menheniott, TR; Peterson, AJ; O'Connor, L; Lee, KS; Kalantzis, A; Kondova, I; Bontrop, RE; Bell, KM; Giraud, AS,期刊：Gastroenterology, 页码：1823-1835 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Gastrokines are stomach mucus cell-secreted proteins; 2 gastrokines are known, GKN1 and GKN2. Gastrokine expression is lost in gastric cancer, indicating a possible function in tumor suppression. We ha...
- CpG Methylation and Reduced Expression of O-6-Methylguanine DNA Methyltransferase Is Associated With Helicobacter pylori Infection
[作者：Sepulveda, AR; Yao, Y; Yan, W; Park, DI; Kim, JJ; Gooding, W; Abudayyeh, S; Graham, DY,期刊：Gastroenterology, 页码：1836-U55 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: The gastric epithelium genome undergoes extensive epigenetic alterations during Helicobacter pylori-induced gastritis. Expression of the gene encoding the DNA repair protein O6-methylguanine DNA methyl...
- Gastric Bypass Increases Energy Expenditure in Rats
[作者：Bueter, M; Lowenstein, C; Olbers, T; Wang, M; Cluny, NL; Bloom, SR; Sharkey, KA; Lutz, TA; Le Roux, CW,期刊：Gastroenterology, 页码：1845-U56 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Mechanisms underlying weight loss maintenance after gastric bypass are poorly understood. Our aim was to examine the effects of gastric bypass on energy expenditure in rats. METHODS: Thirty diet-induce...
- Aberrant DNA Methylation in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency
[作者：Goel, A; Xicola, RM; Nguyen, TP; Doyle, BJ; Sohn, VR; Bandipalliam, P; Rozek, LS; Reyes, J; Cordero, C; Balaguer, F; Castells, A; Jover, R; Andreu, M; Syngal, S; Boland, CR; Llor, X,期刊：Gastroenterology, 页码：1854-U57 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Approximately half of the families that fulfill Amsterdam criteria for Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) do not have evidence of the germline mismatch repair gene muta...
- Cooperation Between the Thyroid Hormone Receptor TR alpha 1 and the WNT Pathway in the Induction of Intestinal Tumorigenesis
[作者：Kress, E; Skah, S; Sirakov, M; Nadjar, J; Gadot, N; Scoazec, JY; Samarut, J; Plateroti, M,期刊：Gastroenterology, 页码：1863-U58 , 文章类型： Article，,卷期：2010年138-5]
- BACKGROUND & AIMS: Colorectal tumorigenesis is a multistep process involving the alteration of oncogenes and tumor suppressor genes, leading to the deregulation of molecular pathways that govern intestinal homeostasis. W...
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