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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共51条记录   Spontaneous Autoimmune Dacryoadenitis in Aged CD25KO Mice [作者：Rahimy, E; Pitcher, JD; Pangelinan, SB; Chen, W; Farley, WJ; Niederkorn, JY; Stern, ME; Li, DQ; Pflugfelder, SC; De Paiva, CS,期刊：American Journal of Pathology, 页码：744-753 , 文章类型： Article，,卷期：2010年177-2] To investigate time-related immunopathological changes in the lacrimal glands (LGs) of CD25KO mice, we examined LGs of C57BL/6 (wild-type) and CD25KO mice at 8, 12, and 16 weeks of age. T cell infiltration was quantified... HIV-Associated Nephropathy Role of Mammalian Target of Rapamycin Pathway [作者：Kumar, D; Konkimalla, S; Yadav, A; Sataranatarajan, K; Kasinath, BS; Chander, PN; Singhal, PC,期刊：American Journal of Pathology, 页码：813-821 , 文章类型： Article，,卷期：2010年177-2] Both glomerular and tubular lesions are characterized by a proliferative phenotype in HIV-associated nephropathy. We hypothesized that mammalian target of rapamycin (mTOR) contributes to the development of the HIVAN phen... Mast Cells and Th17 Cells Contribute to the Lymphoma-Associated Pro-Inflammatory Microenvironment of Angioimmunoblastic T-Cell Lymphoma [作者：Tripodo, C; Gri, G; Piccaluga, PP; Frossi, B; Guarnotta, C; Piconese, S; Franco, G; Vetri, V; Pucillo, CE; Florena, AM; Colombo, MP; Pileri, SA,期刊：American Journal of Pathology, 页码：792-802 , 文章类型： Article，,卷期：2010年177-2] Reports focusing on the immunological microenvironment of peripheral T-cell lymphomas (PTCL) are rare. Here we studied the reciprocal contribution of regulatory (Treg) and interleukin-17-producing (Th17) T-cells to the c... S100A6 Overexpression Is Associated with Poor Prognosis and Is Epigenetically Up-Regulated in Gastric Cancer [作者：Wang, XH; Zhang, LH; Zhong, XY; Xing, XF; Liu, YQ; Niu, ZJ; Peng, Y; Du, H; Zhang, GG; Hu, Y; Liu, N; Zhu, YB; Ge, SH; Zhao, W; Lu, AP; Li, JY; Ji, JF,期刊：American Journal of Pathology, 页码：586-597 , 文章类型： Article，,卷期：2010年177-2] S100A6 has been implicated in a variety of biological functions as well as tumorigenesis. In this study, we investigated the expression status of S100A6 in relation to the clinicopathological features and prognosis of pa... Inhibition of NF-kappa B Signaling Reduces Virus Load and Gammaherpesvirus-Induced Pulmonary Fibrosis [作者：Krug, LT; Torres-Gonzalez, E; Qin, QH; Sorescu, D; Rojas, M; Stecenko, A; Speck, SH; Mora, AL,期刊：American Journal of Pathology, 页码：608-621 , 文章类型： Article，,卷期：2010年177-2] Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disorder of unknown etiology. Several studies have demonstrated an association between pulmonary infection with a herpesvirus and IPF. Based on those obse... Therapeutic Effects of Vitamin D Analogs on Cardiac Hypertrophy in Spontaneously Hypertensive Rats [作者：Kong, JA; Kim, GH; Wei, MJ; Sun, T; Li, G; Liu, SQ; Li, XM; Bhan, I; Zhao, Q; Thadhani, R; Li, YC,期刊：American Journal of Pathology, 页码：622-631 , 文章类型： Article，,卷期：2010年177-2] Vitamin D inhibits renin expression and blocks the compensatory induction of renin associated with the use of renin-angiotensin system inhibitors. Here we test the therapeutic effects of two commonly used vitamin D analo... Hepatic Hyperplasia Associated with Discordant Xenogeneic Parenchymal-Nonparenchymal Interactions in Human Hepatocyte-Repopulated Mice [作者：Utoh, R; Tateno, C; Kataoka, M; Tachibana, A; Masumoto, N; Yamasaki, C; Shimada, T; Itamoto, T; Asahara, T; Yoshizato, K,期刊：American Journal of Pathology, 页码：654-665 , 文章类型： Article，,卷期：2010年177-2] Liver mass is optimized in relation to body mass. Rat (r) and human (h) hepatocytes were transplanted into liver-injured immunodeficient mice and allowed to proliferate for 3 or 11 weeks, respectively, when the transplan... Vitamin D Receptor Negatively Regulates Bacterial-Stimulated NF-kappa B Activity in Intestine [作者：Wu, SP; Liao, AP; Xia, YL; Li, YC; Li, JD; Sartor, RB; Sun, J,期刊：American Journal of Pathology, 页码：686-697 , 文章类型： Article，,卷期：2010年177-2] Vitamin D receptor (VDR) plays an essential role in gastrointestinal inflammation. Most investigations have focused on the immune response; however, how bacteria regulate VDR and how VDR modulates the nuclear factor (NF)... Transcriptional Control of Tight Junction Proteins via a Protein Kinase C Signal Pathway in Human Telomerase Reverse Transcriptase-Transfected Human Pancreatic Duct Epithelial Cells [作者：Yamaguchi, H; Kojima, T; Ito, T; Kimura, Y; Imamura, M; Son, S; Koizumi, J; Murata, M; Nagayama, M; Nobuoka, T; Tanaka, S; Hirata, K; Sawada, N,期刊：American Journal of Pathology, 页码：698-712 , 文章类型： Article，,卷期：2010年177-2] In human pancreatic cancer, integral membrane proteins of tight junction claudins are abnormally regulated, making these proteins promising molecular diagnostic and therapeutic targets. However, the regulation of claudin... Natural Killer Cells Promote Tissue Injury and Systemic Inflammatory Responses During Fatal Ehrlichia-Induced Toxic Shock-Like Syndrome [作者：Stevenson, HL; Estes, MD; Thirumalapura, NR; Walker, DH; Ismail, N,期刊：American Journal of Pathology, 页码：766-776 , 文章类型： Article，,卷期：2010年177-2] Human monocytotropic ehrlichiosis is caused by Ehrlichia chaffeensis, a Gram-negative bacterium lacking lipopolysaccharide. We have shown that fatal murine ehrlichiosis is associated with CD8(+)T cell-mediated tissue dam... Impact of Short-Term Combined Antiretroviral Therapy on Brain Virus Burden in Simian Immunodeficiency Virus-Infected and CD8(+) Lymphocyte-Depleted Rhesus Macaques [作者：Annamalai, L; Bhaskar, V; Pauley, DR; Knight, H; Williams, K; Lentz, M; Ratai, E; Westmoreland, SV; Gonzalez, RG; O'Neil, SP,期刊：American Journal of Pathology, 页码：777-791 , 文章类型： Article，,卷期：2010年177-2] Antiretroviral drugs suppress virus burden in the cerebrospinal fluid of HIV-infected individuals; however, the direct effect of antiretrovirals on virus replication in brain parenchyma is poorly understood. We investiga... Abnormal Presence of the Matrix Extracellular Phosphoglycoprotein-Derived Acidic Serine- and Aspartate-Rich Motif Peptide in Human Hypophosphatemic Dentin [作者：Boukpessi, T; Gaucher, C; Leger, T; Salmon, B; Le Faouder, J; Willig, C; Rowe, PS; Garabedian, M; Meilhac, O; Chaussain, C,期刊：American Journal of Pathology, 页码：803-812 , 文章类型： Article，,卷期：2010年177-2] Severe dental troubles are associated with X-linked hypophosphatemic rickets and are mainly related to impaired dentin mineralization. In dentin matrix, matrix extracellular phosphoglycoprotein (MEPE) may be protected fr... Long-Term Expression of Tissue-Inhibitor of Matrix Metalloproteinase-1 in the Murine Central Nervous System Does Not Alter the Morphological and Behavioral Phenotype but Alleviates the Course of Experimental Allergic Encephalomyelitis [作者：Althoff, GEM; Wolfer, DP; Timmesfeld, N; Kanzler, B; Schrewe, H; Pagenstecher, A,期刊：American Journal of Pathology, 页码：840-853 , 文章类型： Article，,卷期：2010年177-2] Tissue inhibitors of metalloproteinases (TIMPs) are a family of closely related proteins that inhibit matrix metalloproteinases (MMPs). In the central nervous system (CNS), TIMPs 2, 3, and 4 are constitutively expressed ... In Vivo Assessment of Acute UVB Responses in Normal and Xeroderma Pigmentosum (XP-C) Skin-Humanized Mouse Models [作者：Garcia, M; Llames, S; Garcia, E; Meana, A; Cuadrado, N; Recasens, M; Puig, S; Nagore, E; Illera, N; Jorcano, JL; Del Rio, M; Larcher, F,期刊：American Journal of Pathology, 页码：865-872 , 文章类型： Article，,卷期：2010年177-2] In vivo studies of UVB effects on human skin are precluded by ethical and technical arguments on volunteers and inconceivable in cancer-prone patients such as those affected with Xeroderma Pigmentosum (XP). Establishing ... Mesenchymal Stem Cells, Used As Bait, Disclose Tissue Binding Sites A Tool in the Search for the Niche? [作者：Ratliff, BB; Singh, N; Yasuda, K; Park, HC; Addabbo, F; Ghaly, T; Rajdev, M; Jasmin, JF; Plotkin, M; Lisanti, MP; Goligorsky, MS,期刊：American Journal of Pathology, 页码：873-883 , 文章类型： Article，,卷期：2010年177-2] We developed an ex vivo approach characterizing renal mesenchymal stem cell (MSC) adhesion to kidney sections. Specificity of MSC adhesion was confirmed by demonstrating a) 3T3 cells displayed 10-fold lower adhesion, and... A Differentiation-Based MicroRNA Signature Identifies Leiomyosarcoma as a Mesenchymal Stem Cell-Related Malignancy [作者：Danielson, LS; Menendez, S; Attolini, CSO; Guijarro, MV; Bisogna, M; Wei, JJ; Socci, ND; Levine, DA; Michor, F; Hernando, E,期刊：American Journal of Pathology, 页码：908-917 , 文章类型： Article，,卷期：2010年177-2] Smooth muscle (SM) is a spontaneously contractile tissue that provides physical support and function to organs such as the uterus. Uterine smooth muscle related neoplasia comprise common well-differentiated benign lesion...