- Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer
[作者：Smith, JJ; Deane, NG; Wu, F; Merchant, NB; Zhang, B; Jiang, AX; Lu, PC; Johnson, JC; Schmidt, C; Bailey, CE; Eschrich, S; Kis, C; Levy, S; Washington, MK; Heslin, MJ; Coffey, RJ; Yeatman, TJ; Shyr, Y; Beauchamp, RD,期刊：Gastroenterology, 页码：958-968 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Staging inadequately predicts metastatic risk in patients with colon cancer. We used a gene expression profile derived from invasive, murine colon cancer cells that were highly metastatic in an immunoc...
- Adverse Outcomes in Alaska Natives Who Recovered From or Have Chronic Hepatitis C Infection
[作者：McMahon, BJ; Bruden, D; Bruce, MG; Livingston, S; Christensen, C; Homan, C; Hennessy, TW; Williams, J; Sullivan, D; Rosen, HR; Gretch, D,期刊：Gastroenterology, 页码：922-U157 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: The factors associated with adverse outcome from hepatitis C virus (HCV) infection are incompletely understood. To determine the incidence and risk factors associated with the development of endstage l...
- Chronic Hepatitis C Is Associated With Peripheral Rather Than Hepatic Insulin Resistance
[作者：Milner, KL; van der Poorten, D; Trenell, M; Jenkins, AB; Xu, AM; Smythe, G; Dore, GJ; Zekry, A; Weltman, M; Fragomeli, V; George, J; Chisholm, DJ,期刊：Gastroenterology, 页码：932-U170 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Chronic hepatitis C (CHC) is associated with insulin resistance (IR), liver steatosis (genotype 3), and increased diabetes risk. The site and mechanisms of IR are unclear. METHODS: We compared cross-se...
- Chronic Pancreatitis Is Associated With Disease-Specific Regulatory T-Cell Responses
[作者：Schmitz-Winnenthal, H; Pietsch, DHK; Schimmack, S; Bonertz, A; Udonta, F; Ge, YZ; Galindo, L; Specht, S; Volk, C; Zgraggen, K; Koch, M; Buchler, MW; Weitz, J; Beckhove, P,期刊：Gastroenterology, 页码：1178-1188 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Chronic pancreatitis is characterized by alternating phases of acute inflammation and quiescent disease. Involvement of T-cell responses has been suggested, but pancreatitis-specific T cells have not b...
- The Histone Demethylase RBP2 Is Overexpressed in Gastric Cancer and Its Inhibition Triggers Senescence of Cancer Cells
[作者：Zeng, JP; Ge, Z; Wang, LX; Li, Q; Wang, N; Bjorkholm, M; Jia, JH; Xu, DW,期刊：Gastroenterology, 页码：981-992 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: The aberrant expression of histone-modifying enzymes such as histone deacetylases contributes to oncogenesis. It is unclear whether RBP2, a newly identified histone demethylase, is involved in cancer d...
- NFAT-Induced Histone Acetylation Relay Switch Promotes c-Myc-Dependent Growth in Pancreatic Cancer Cells
[作者：Koenig, A; Linhart, T; Schlengemann, K; Reutlinger, K; Wegele, J; Adler, G; Singh, G; Hofmann, L; Kunsch, S; Buch, T; Schafer, E; Gress, TM; Fernandez-Zapico, ME; Ellenrieder, V,期刊：Gastroenterology, 页码：1189-U487 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Induction of immediate early transcription factors (ITF) represents the first transcriptional program controlling mitogen-stimulated cell cycle progression in cancer. Here, we examined the transcriptio...
- Rapid HCV-RNA Decline With Once Daily TMC435: A Phase I Study in Healthy Volunteers and Hepatitis C Patients
[作者：Reesink, HW; Fanning, GC; Abou Farha, K; Weegink, C; Van Vliet, A; van 't Klooster, G; Lenz, O; Aharchi, F; Marien, K; Van Remoortere, P; de Kock, H; Broeckaert, F; Meyvisch, P; Van Beirendonck, E; Simmen, K; Verloes, R,期刊：Gastroenterology, 页码：913-921 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: The search for targeted anti-hepatitis C virus (HCV) drugs is driven by the adverse effect profile and limited efficacy of the current standard of care (pegylated interferon-alpha/ribavirin). In a firs...
- Silibinin and Related Compounds Are Direct Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase
[作者：Ahmed-Belkacem, A; Ahnou, N; Barbotte, L; Wychowski, C; Pallier, C; Brillet, R; Pohl, RT; Pawlotsky, JM,期刊：Gastroenterology, 页码：1112-1122 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Silymarin is a mixture of flavonolignans extracted from the milk thistle. Silymarin contains several molecules, including silibinin A, silibinin B, isosilibinin A, isosilibinin B, silicristin, and sili...
- Pancreatic Duct Glands Are Distinct Ductal Compartments That React to Chronic Injury and Mediate Shh-Induced Metaplasia
[作者：Strobel, O; Rosow, DE; Rakhlin, EY; Lauwers, GY; Trainor, AG; Alsina, J; Fernandez-Del Castillo, C; Warshaw, AL; Thayer, SP,期刊：Gastroenterology, 页码：1166-1177 , 文章类型： Article，,卷期：2010年138-3]
- BACKGROUND & AIMS: Pancreatic intraepithelial neoplasia (PanIN) are pancreatic cancer precursor lesions of unclear origin and significance. PanIN aberrantly express sonic hedgehog (Shh), an initiator of pancreatic cancer...
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