- Catalytic Mechanism of S-type Phycobiliprotein Lyase CHAPERONE-LIKE ACTION AND FUNCTIONAL AMINO ACID RESIDUES
[作者:Kupka, M; Zhang, J; Fu, WL; Tu, JM; Bohm, S; Su, P; Chen, Y; Zhou, M; Scheer, H; Zhao, KH,期刊:Journal of Biological Chemistry, 页码:36405-36414 , 文章类型: Article,,卷期:2009年284-52]
- The phycobilin: cysteine 84-phycobiliprotein lyase, CpcS1, catalyzes phycocyanobilin (PCB) and phycoerythrobilin (PEB) attachment at nearly all cysteine 82 binding sites (consensus numbering) of phycoerythrin, phycoeryth...
- Extracellular Loops 2 and 4 of GLYT2 Are Required for N-Arachidonylglycine Inhibition of Glycine Transport
[作者:Edington, AR; McKinzie, AA; Reynolds, AJ; Kassiou, M; Ryan, RM; Vandenberg, RJ,期刊:Journal of Biological Chemistry, 页码:36424-36430 , 文章类型: Article,,卷期:2009年284-52]
- Concentrations of extracellular glycine in the central nervous system are regulated by Na+/Cl--dependent glycine transporters, GLYT1 and GLYT2. N-Arachidonylglycine (NAGly) is an endogenous inhibitor of GLYT2 with little...
- Hepatitis C Virus Impairs p53 via Persistent Overexpression of 3 beta-Hydroxysterol Delta 24-Reductase
[作者:Nishimura, T; Kohara, M; Izumi, K; Kasama, Y; Hirata, Y; Huang, Y; Shuda, M; Mukaidani, C; Takano, T; Tokunaga, Y; Nuriya, H; Satoh, M; Saito, M; Kai, C; Tsukiyama-Kohara, K,期刊:Journal of Biological Chemistry, 页码:36442-36452 , 文章类型: Article,,卷期:2009年284-52]
- Persistent infection with hepatitis C virus (HCV) induces tumorigenicity in hepatocytes. To gain insight into the mechanisms underlying this process, we generated monoclonal antibodies on a genome-wide scale against an H...
- Aminopyridines Potentiate Synaptic and Neuromuscular Transmission by Targeting the Voltage-activated Calcium Channel beta Subunit
[作者:Wu, ZZ; Li, DP; Chen, SR; Pan, HL,期刊:Journal of Biological Chemistry, 页码:36453-36461 , 文章类型: Article,,卷期:2009年284-52]
- Aminopyridines such as 4-aminopyridine (4-AP) are widely used as voltage-activated K+ (Kv) channel blockers and can improve neuromuscular function in patients with spinal cord injury, myasthenia gravis, or multiple scler...
- Overexpression, Isolation, and Spectroscopic Characterization of the Bidirectional [NiFe] Hydrogenase from Synechocystis sp PCC 6803
[作者:Germer, F; Zebger, I; Saggu, M; Lendzian, F; Schulz, R; Appel, J,期刊:Journal of Biological Chemistry, 页码:36462-36472 , 文章类型: Article,,卷期:2009年284-52]
- The bidirectional [NiFe] hydrogenase of the cyanobacterium Synechocystis sp. PCC 6803 was purified to apparent homogeneity by a single affinity chromatography step using a Synechocystis mutant with a Strep-tag II fused t...
- MODY7 Gene, KLF11, Is a Novel p300-dependent Regulator of Pdx-1 (MODY4) Transcription in Pancreatic Islet beta Cells
[作者:Fernandez-Zapico, ME; van Velkinburgh, JC; Gutierrez-Aguilar, R; Neve, B; Froguel, P; Urrutia, R; Stein, R,期刊:Journal of Biological Chemistry, 页码:36482-36490 , 文章类型: Article,,卷期:2009年284-52]
- Pdx-1 (pancreatic-duodenal homeobox-1), a MODY4 homeodomain transcription factor, serves as a master regulator in the pancreas because of its importance during organogenesis and in adult islet insulin-producing beta cell...
- RNA Interference in Trypanosoma brucei ROLE OF THE N-TERMINAL RGG DOMAIN AND THE POLYRIBOSOME ASSOCIATION OF ARGONAUTE
[作者:Shi, HF; Chamond, N; Djikeng, A; Tschudi, C; Ullu, E,期刊:Journal of Biological Chemistry, 页码:36511-36520 , 文章类型: Article,,卷期:2009年284-52]
- Argonaute proteins (AGOs) are central to RNA interference (RNAi) and related silencing pathways. At the core of the RNAi pathway in the ancient parasitic eukaryote Trypanosoma brucei is a single Argonaute protein, TbAGO1...
- Sequestosome-1/p62 Is the Key Intracellular Target of Innate Defense Regulator Peptide
[作者:Yu, HB; Kielczewska, A; Rozek, A; Takenaka, S; Li, YL; Thorson, L; Hancock, REW; Guarna, MM; North, JR; Foster, LJ; Donini, O; Finlay, BB,期刊:Journal of Biological Chemistry, 页码:36007-36011 , 文章类型: Article,,卷期:2009年284-52]
- Innate defense regulator-1 (IDR-1) is a synthetic peptide with no antimicrobial activity that enhances microbial infection control while suppressing inflammation. Previously, the effects of IDR-1 were postulated to impac...
- The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCFCdc4
[作者:Kleiger, G; Hao, B; Mohl, DA; Deshaies, RJ,期刊:Journal of Biological Chemistry, 页码:36012-36023 , 文章类型: Article,,卷期:2009年284-52]
- Ubiquitin ligases, together with their cognate ubiquitin-conjugating enzymes, are responsible for the ubiquitylation of proteins, a process that regulates a myriad of eukaryotic cellular functions. The first cullin-RING ...
- Role of Microtubules in Stress Granule Assembly MICROTUBULE DYNAMICAL INSTABILITY FAVORS THE FORMATION OF MICROMETRIC STRESS GRANULES IN CELLS
[作者:Chernov, KG; Barbet, A; Hamon, L; Ovchinnikov, LP; Curmi, PA; Pastre, D,期刊:Journal of Biological Chemistry, 页码:36569-36580 , 文章类型: Article,,卷期:2009年284-52]
- Following exposure to various stresses (arsenite, UV, hyperthermia, and hypoxia), mRNAs are assembled into large cytoplasmic bodies known as "stress granules," in which mRNAs and associated proteins may be processed by s...
- Epidermal Growth Factor Receptor Translocation to the Mitochondria REGULATION AND EFFECT
[作者:Demory, ML; Boerner, JL; Davidson, R; Faust, W; Miyake, T; Lee, I; Huttemann, M; Douglas, R; Haddad, G; Parsons, SJ,期刊:Journal of Biological Chemistry, 页码:36592-36604 , 文章类型: Article,,卷期:2009年284-52]
- Co-overexpression of the epidermal growth factor (EGF) receptor (EGFR) and c-Src frequently occurs in human tumors and is linked to enhanced tumor growth. In experimental systems this synergistic growth requires EGF-depe...
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