- Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma
[作者:Navarro, A; Diaz, T; Martinez, A; Gaya, A; Pons, A; Gel, B; Codony, C; Ferrer, G; Martinez, C; Montserrat, E; Monzo, M,期刊:Blood, 页码:2945-2951 , 文章类型: Article,,卷期:2009年114-14]
- The behavior of classic Hodgkin lymphoma (cHL) is determined by both the intrinsic features of the tumor cells and the characteristics of the microenvironment, making the analysis of entire lymph nodes an effective appro...
- Mndal, a new interferon-inducible family member, is highly polymorphic, suppresses cell growth, and may modify plasmacytoma susceptibility
[作者:Zhang, K; Kagan, D; DuBois, W; Robinson, R; Bliskovsky, V; Vass, WC; Zhang, SL; Mock, BA,期刊:Blood, 页码:2952-2960 , 文章类型: Article,,卷期:2009年114-14]
- The human HIN-200 gene cluster and its mouse counterpart, the interferon inducible-200 (Ifi200) family, both on Chr 1, are associated with several diseases, including solid tumors and lupus. Our study was initiated to id...
- Inhibition of the SDF-1 alpha-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice
[作者:Kawaguchi, A; Orba, Y; Kimura, T; Iha, H; Ogata, M; Tsuji, T; Ainai, A; Sata, T; Okamoto, T; Hall, WW; Sawa, H; Hasegawa, H,期刊:Blood, 页码:2961-2968 , 文章类型: Article,,卷期:2009年114-14]
- Adult T-cell leukemia (ATL) is a T-cell malignancy caused by human T lymphotropic virus type I, and presents as an aggressive leukemia with characteristic widespread leukemic cell infiltration into visceral organs and sk...
- Molecular profiling of CD3(-)CD4(+) T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways
[作者:Ravoet, M; Sibille, C; Gu, CY; Libin, M; Haibe-Kains, B; Sotiriou, C; Goldman, M; Roufosse, F; Willard-Gallo, K,期刊:Blood, 页码:2969-2983 , 文章类型: Article,,卷期:2009年114-14]
- The clonal CD3(-)CD4(+) T-cell population characterizing lymphocytic variant hypereosinophilic syndrome (L-HES) persists for years, with a subgroup of patients ultimately progressing to T lymphoma. The molecular changes ...
- AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)
[作者:Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS,期刊:Blood, 页码:2984-2992 , 文章类型: Article,,卷期:2009年114-14]
- Activating mutations in the receptor tyrosine kinase FLT3 are present in up to approximately 30% of acute myeloid leukemia (AML) patients, implicating FLT3 as a driver of the disease and therefore as a target for therapy...
- High Id1 expression is associated with poor prognosis in 237 patients with acute myeloid leukemia
[作者:Tang, RP; Hirsch, P; Fava, F; Lapusan, S; Marzac, C; Teyssandier, I; Pardo, J; Marie, JP; Legrand, O,期刊:Blood, 页码:2993-3000 , 文章类型: Article,,卷期:2009年114-14]
- Inhibitors of differentiation (Id) are a group of dominant inhibitors of basic helix-loop-helix transcriptional factors, which promote excessive proliferation, and also protect cells against drug-induced apoptosis in mam...
- Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status
[作者:Silva, FPG; Swagemakers, SMA; Erpelinck-Verschueren, C; Wouters, BJ; Delwel, R; Vrieling, H; van der Spek, P; Valk, PJM; Giphart-Gassler, M,期刊:Blood, 页码:3001-3007 , 文章类型: Article,,卷期:2009年114-14]
- Minimally differentiated acute myeloid leukemia (AML-M0) is defined by immature morphology and expression of early hematologic markers. By gene expression profiling (GEP) and subsequent unsupervised analysis of 35 AML-M0...
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