- Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal
[作者:Heuser, M; Sly, LM; Argiropoulos, B; Kuchenbauer, F; Lai, C; Weng, A; Leung, M; Lin, G; Brookes, C; Fung, S; Valk, PJ; Delwel, R; Lowenberg, B; Krystal, G; Humphries, RK,期刊:Blood, 页码:3983-3993 , 文章类型: Article,,卷期:2009年114-19]
- Although the cancer stem cell (CSC) concept implies that CSCs are rare, recent reports suggest that CSCs may be frequent in some cancers. We hypothesized that the proportion of leukemia stem cells would vary as a functio...
- Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome
[作者:Abarrategui-Garrido, C; Martinez-Barricarte, R; Lopez-Trascasa, M; de Cordoba, SR; Sanchez-Corral, P,期刊:Blood, 页码:4261-4271 , 文章类型: Article,,卷期:2009年114-19]
- The factor H-related protein family (CFHR) is a group of minor plasma proteins genetically and structurally related to complement factor H (fH). Notably, deficiency of CFHR1/CFHR3 associates with protection against age-r...
- Altered fibrin clot structure/function in patients with idiopathic venous thromboembolism and in their relatives
[作者:Undas, A; Zawilska, K; Ciesla-Dul, M; Lehmann-Kopydlowska, A; Skubiszak, A; Ciepluch, K; Tracz, W,期刊:Blood, 页码:4272-4278 , 文章类型: Article,,卷期:2009年114-19]
- We tested the hypothesis that fibrin structure/function is unfavorably altered in patients after idiopathic venous thromboembolism (VTE) and their relatives. Ex vivo plasma fibrin clot permeability, turbidimetry, and eff...
- How I treat EBV lymphoproliferation
[作者:Heslop, HE,期刊:Blood, 页码:4002-4008 , 文章类型: Article,,卷期:2009年114-19]
- Epstein-Barr virus (EBV)-associated B-cell lymphoproliferation is a life-threatening complication after hematopoietic stem cell or solid organ transplantation resulting from outgrowth of EBV-infected B cells that would n...
- Deferasirox pharmacokinetics in patients with adequate versus inadequate response
[作者:Chirnomas, D; Smith, AL; Braunstein, J; Finkelstein, Y; Pereira, L; Bergmann, AK; Grant, FD; Paley, C; Shannon, M; Neufeld, EJ,期刊:Blood, 页码:4009-4013 , 文章类型: Article,,卷期:2009年114-19]
- Tens of thousands of transfusion-dependent (eg, thalassemia) patients worldwide suffer from chronic iron overload and its potentially fatal complications. The oral iron chelator deferasirox has become commercially availa...
- Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation
[作者:Leen, AM; Christin, A; Myers, GD; Liu, H; Cruz, CR; Hanley, PJ; Kennedy-Nasser, AA; Leung, KS; Gee, AP; Krance, RA; Brenner, MK; Heslop, HE; Rooney, CM; Bollard, CM,期刊:Blood, 页码:4283-4292 , 文章类型: Article,,卷期:2009年114-19]
- Viral infection or reactivation remains a major cause of morbidity and mortality after allogeneic stem cell transplantation. We now show that infusions of single cytotoxic T lymphocyte (CTL) lines (5 x 10(6)-1.35 x 10(8)...
- Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units
[作者:Verneris, MR; Brunstein, CG; Barker, J; MacMillan, ML; Defor, T; McKenna, DH; Burke, MJ; Blazar, BR; Miller, JS; McGlave, PB; Weisdorf, DJ; Wagner, JE,期刊:Blood, 页码:4293-4299 , 文章类型: Article,,卷期:2009年114-19]
- Umbilical cord blood (UCB) transplantation is potentially curative for acute leukemia. This analysis was performed to identify risk factors associated with leukemia relapse following myeloablative UCB transplantation. Ac...
- A protective role for early oral exposures in the etiology of young adult Hodgkin lymphoma
[作者:Cozen, W; Hamilton, AS; Zhao, P; Salam, MT; Deapen, DM; Nathwani, BN; Weiss, LM; Mack, TM,期刊:Blood, 页码:4014-4020 , 文章类型: Article,,卷期:2009年114-19]
- The pattern of adolescent/young adult Hodgkin lymphoma (YAHL) suggests causation by a relatively late infection with a common childhood virus, but no causal virus has been found. Susceptibility is heritable and linked to...
- Repulsive axon guidance molecule Slit3 is a novel angiogenic factor
[作者:Zhang, B; Dietrich, UM; Geng, JG; Bicknell, R; Esko, JD; Wang, LC,期刊:Blood, 页码:4300-4309 , 文章类型: Article,,卷期:2009年114-19]
- Slits are large, secreted repulsive axon guidance molecules. Recent genetic studies revealed that the Slit3 is dispensable for neural development but required for non-neuron-related developmental processes, such as the g...
- Bone marrow stem and progenitor cell contribution to neovasculogenesis is dependent on model system with SDF-1 as a permissive trigger
[作者:Madlambayan, GJ; Butler, JM; Hosaka, K; Jorgensen, M; Fu, DT; Guthrie, SM; Shenoy, AK; Brank, A; Russell, KJ; Otero, J; Siemann, DW; Scott, EW; Cogle, CR,期刊:Blood, 页码:4310-4319 , 文章类型: Article,,卷期:2009年114-19]
- Adult bone marrow (BM) contributes to neovascularization in some but not all settings, and reasons for these discordant results have remained unexplored. We conducted novel comparative studies in which multiple neovascul...
- Cutaneous tumor lysis syndrome in a patient with HTLV-1 adult T-cell lymphoma/leukemia
[作者:Bouaziz, JD; Cordel, N; Hickman, G; Fieschi, C; Ortonne, N; Bagot, M,期刊:Blood, 页码:4320-4321 , 文章类型: Letter,,卷期:2009年114-19]
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