- Cyclic glycopeptidomimetics through a versatile sugar-based scaffold
[作者:Altamura, M; Dragoni, E; Infantino, AS; Legnani, L; Ludbrook, SB; Menchi, G; Toma, L; Nativi, C,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3841-3844 , 文章类型: Article,,卷期:2009年19-14]
- Cyclic peptidomimetics are attracting structures to obtain a distinct, bioactive conformation. Even more attractive are sugar-containing cyclic peptidomimetics which present turn structures induced by the pyranose ring w...
- Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product
[作者:Hayashi, Y; Sankar, K; Ishikawa, H; Nozawa, Y; Mizoue, K; Kakeya, H,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3863-3865 , 文章类型: Article,,卷期:2009年19-14]
- The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry. (C) 2009 Elsevier Ltd. All rights reserved.
- Rapid identification of improved protein ligands using peptoid microarrays
[作者:Lim, HS; Reddy, MM; Xiao, XS; Wilson, J; Wilson, R; Connell, S; Kodadek, T,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3866-3869 , 文章类型: Article,,卷期:2009年19-14]
- A rapid array-based protocol is presented by which a modest affinity protein-binding small molecule can be appended to a library of peptoids via click chemistry. The array can then be screened for improved ligands that e...
- Organocatalysis with endogenous compounds: Towards novel non-enzymatic reactions
[作者:Alberg, DG; Poulsen, TB; Bertelsen, S; Christensen, KL; Birkler, RD; Johannsen, M; Jorgensen, KA,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3888-3891 , 文章类型: Article,,卷期:2009年19-14]
- The aldol reaction of the endogeneous compounds acetone and methylglyoxal has been studied using organocatalysis in relation to biologically relevant non-enzymatic reactions. Under preparative conditions, 3-hydroxy-2,5-h...
- Highly efficient synthesis of vinyl substituted triazoles by Au(I) catalyzed alkyne activation
[作者:Duan, HF; Yan, WM; Sengupta, S; Shi, XD,期刊:Bioorganic & Medicinal Chemistry Letters, 页码:3899-3902 , 文章类型: Article,,卷期:2009年19-14]
- Au(I) catalyzed 1,2,3-triazole addition to non-activated alkyne was reported. A large group of substituted NH-1,2,3-triazoles were suitable for this transformation along with both internal and terminal alkynes. The N-1 a...
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