- Improvement of Biodistribution and Therapeutic Index via Increase of Polyethylene Glycol on Drug-carrying Liposomes in an HT-29/luc Xenografted Mouse Model
[作者：Chow, TH; Lin, YY; Hwang, JJ; Wang, HE; Tseng, YL; Wang, SJ; Liu, RS; Lin, WJ; Yang, CS; Ting, G,期刊：Anticancer Research, 页码：2111-2120 , 文章类型： Article，,卷期：2009年29-6]
- Liposomes modified with a high concentration of polyethylene glycol (PEG) could significantly prolong the retention time of the carried drug in the circulation, thus improving the drug accumulation in the tumor. In this ...
- Renal Capsule-Parathymic Lymph Node Complex: A New In Vivo Metastatic Model in Rats
[作者：Trencsenyi, G; Kertai, P; Bako, F; Hunyadi, J; Marian, T; Hargitai, Z; Pocsi, I; Muranyi, E; Hornyak, L; Banfalvi, G,期刊：Anticancer Research, 页码：2121-2126 , 文章类型： Article，,卷期：2009年29-6]
- Background: The ultimate cause of cancer death is, in most cases, the appearance of metastases. The aim of the present study was to contribute to animal experimental investigations of metastatic tumor development. Materi...
- Mechanisms of Escape from Trastuzumab-mediated ADCC in Esophageal Squamous Cell Carcinoma: Relation to Susceptibility to Perforin-granzyme
[作者：Kawaguchi, Y; Kono, K; Mizukami, Y; Mimura, K; Fujii, H,期刊：Anticancer Research, 页码：2137-2146 , 文章类型： Article，,卷期：2009年29-6]
- Background: The escape mechanisms leading to trastuzumab-resistance are under investigation, but no report has yet described the mechanisms of escape from trastuzumab-mediated antibody-dependent cellular cytotoxicity (AD...
- The Hedgehog Signaling Pathway Plays an Essential Role in Maintaining the CD44(+)CD24(-/Low) Subpopulation and the Side Population of Breast Cancer Cells
[作者：Tanaka, H; Nakamura, M; Kameda, C; Kubo, M; Sato, N; Kuroki, S; Tanaka, M; Katano, M,期刊：Anticancer Research, 页码：2147-2157 , 文章类型： Article，,卷期：2009年29-6]
- The side population (SP) and the CD44(+)/CD24(-/low) population have been reported in separate studies to include more tumorigenic cells than other populations, and to have the ability to form new tumors and undergo hete...
- Antitumor Activity of a Selectively Replication Competent Herpes Simplex Virus (HSV) with Enzyme Prodrug Therapy
[作者：Braidwood, L; Dunn, PD; Hardy, S; Evans, TRJ; Brown, SM,期刊：Anticancer Research, 页码：2159-2166 , 文章类型： Article，,卷期：2009年29-6]
- Background: HSV1790 is an oncolytic virus generated by inserting the enzyme nitroreductase (NTR) into the virus HSV1716. NTR converts the prodrug CB1954 into an active alkylating agent. Materials and Methods: In vitro, 3...
- Differential Effects of Aromatase Inhibitors and Antiestrogens on Estrogen Receptor Expression in Breast Cancer Cells
[作者：Smollich, M; Gotte, M; Fischgrabe, J; Radke, I; Kiesel, L; Wulfing, P,期刊：Anticancer Research, 页码：2167-2171 , 文章类型： Article，,卷期：2009年29-6]
- Background: Estrogen receptors (ER) alpha and beta play an important role in breast cancer. Recently, systemic adjuvant endocrine therapy with selective estrogen receptor modulator (SERM) tamoxifen has been challenged by...
- Demonstration of the Activity of P-glycoprotein by a Semi-automated Fluorometric Method
[作者：Spengler, G; Viveiros, M; Martins, M; Rodrigues, L; Martins, A; Molnar, J; Couto, I; Amaral, L,期刊：Anticancer Research, 页码：2173-2177 , 文章类型： Article，,卷期：2009年29-6]
- Background: We have developed a semi-automated fluorometric method that utilizes ethidium bromide (EB), a common substrate of bacterial efflux pumps. The method is sufficiently sensitive to characterize the efflux pump s...
- (-)-Gossypol Reduces Invasiveness in Metastatic Prostate Cancer Cells
[作者：Huang, YW; Wang, LS; Dowd, MK; Wan, PJ; Lin, YC,期刊：Anticancer Research, 页码：2179-2188 , 文章类型： Article，,卷期：2009年29-6]
- Background: Acquisition of metastatic ability by prostatic cancer cells is the most lethal aspect of prostatic cancer progression. (-)-Gossypol, a polyphenolic compound present in cottonseeds, possesses anti-proliferativ...
- Expression of ERas Oncogene in Gastric Carcinoma
[作者：Kaizaki, R; Yashiro, M; Shinto, O; Yasuda, K; Matsuzaki, T; Sawada, T; Hirakawa, K,期刊：Anticancer Research, 页码：2189-2193 , 文章类型： Article，,卷期：2009年29-6]
- Background: Embryonic stem cell expressed Ras (ERas) oncogene is associated with the tumorigenicity of embryonic stem cells. The aim of this study was to clarify the significance of ERas expression in clinical samples of...
- Riluzole Induces Apoptotic Cell Death in Human Prostate Cancer Cells via Endoplasmic Reticulum Stress
[作者：Akamatsu, K; Shibata, MA; Ito, Y; Sohma, Y; Azuma, H; Otsuki, Y,期刊：Anticancer Research, 页码：2195-2204 , 文章类型： Article，,卷期：2009年29-6]
- Background: Ion channel modulators have been previously associated with cell proliferation and cell death in human cancer cell lines. Materials and Methods: The effects of riluzole, an ion channel modulator, on cell prol...
- Potent Neutralization of Vacuolating Cytotoxin (VacA) of Helicobacter pylori by Immunoglobulins Against the Soluble Recombinant VacA
[作者：Ki, MR; Hong, IH; Park, JK; Hong, KS; Hwang, OK; Han, JY; Ji, AR; Park, SI; Lee, SK; Yoo, SE; Jeong, KS,期刊：Anticancer Research, 页码：2393-2402 , 文章类型： Article，,卷期：2009年29-6]
- Background: The recombinant vacuolating cytotoxin (rVacA) of Helicobacter pylori that retains native conformational epitopes was evaluated as a vaccine antigen for anti-H. pylori treatment. Methods: s1m1 vacA gene fracti...
- Frequent Methylation of Vimentin in Well-differentiated Gastric Carcinoma
[作者：Kitamura, YH; Shirahata, A; Sakata, M; Goto, T; Mizukami, H; Saito, M; Ishibashi, K; Kigawa, G; Nemoto, H; Sanada, Y; Hibi, K,期刊：Anticancer Research, 页码：2227-2229 , 文章类型： Article，,卷期：2009年29-6]
- Background: Recently, it was shown that the vimentin gene, usually activated in mesenchymal cells, was highly methylated in colorectal carcinoma. Materials and Methods: The methylation status of the vimentin gene was exa...
- Methylation of HACE1 in Gastric Carcinoma
[作者：Sakata, M; Kitamura, YH; Sakuraba, K; Goto, T; Mizukami, H; Saito, M; Ishibashi, K; Kigawa, G; Nemoto, H; Sanada, Y; Hibi, K,期刊：Anticancer Research, 页码：2231-2233 , 文章类型： Article，,卷期：2009年29-6]
- Background: We recently examined the methylation status of the HACE1 gene in primary carcinomas derived from 32 patients with colorectal cancer. A significant increase was observed in the maximal tumor size of the tumors...
- Antioxidant and Cyclooxygenase-2-inhibiting Activity of 4,4 '-Biphenol, 2,2 '-Biphenol and Phenol
[作者：Murakami, Y; Ishii, H; Hoshina, S; Takada, N; Ueki, A; Tanaka, S; Kadoma, Y; Ito, S; Machino, M; Fujisawa, S,期刊：Anticancer Research, 页码：2403-2410 , 文章类型： Article，,卷期：2009年29-6]
- The anthropogenic substance 4,4'-biphenol and its analogues are estrogenic and cytotoxic. It has been previously found that synthesized ortho-dimers of phenolic compounds possess potent antioxidative and anti-inflammator...
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