- The carbon monoxide-releasing molecule tricarbonyldichlororuthenium(II) dimer protects human osteoarthritic chondrocytes and cartilage from the catabolic actions of interleukin-1 beta
[作者:Megias, J; Guillen, MI; Bru, A; Gomar, F; Alcaraz, MJ,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:56-61 , 文章类型: Article,,卷期:2008年325-1]
We have investigated the effects of a carbon monoxide-releasing molecule, tricarbonyldichlororuthenium(II) dimer (CORM-2), on catabolic processes in human osteoarthritis (OA) cartilage and chondrocytes activated with ...
- Design and evaluation of S-nitrosylated human serum albumin as a novel anticancer drug
[作者:Katayama, N; Nakajou, K; Komori, H; Uchida, K; Yokoe, JI; Yasui, N; Yamamoto, H; Kai, T; Sato, M; Nakagawa, T; Takeya, M; Maruyama, T; Otagiri, M,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:69-76 , 文章类型: Article,,卷期:2008年325-1]
In recent studies, the cytotoxic activity of NO has been investigated for its potential use in anticancer therapies. Nitrosated human serum albumin (NO-HSA) may act as a reservoir of NO in vivo. However, there are no ...
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