- Crystallographic and biochemical analysis of rotavirus NSP2 with nucleotides reveals a nucleoside diphosphate kinase-like activity
[作者:Kumar, M; Jayaram, H; Carpio, RVD; Jiang, X; Taraporewala, ZF; Jacobson, RH; Patton, JT; Prasad, BVV,期刊:Journal of virology, 页码:12272-12284 , 文章类型: Article,,卷期:2007年81-22]
- Rotavirus, the major pathogen of infantile gastroenteritis, carries a nonstructural protein, NSP2, essential for viroplasm formation and genome replication/packaging. In addition to RNA-binding and helix-destabilizing pr...
- Infection of cardiomyocytes and induction of left ventricle dysfunction by neurovirulent polytropic murine retrovirus
[作者:Khaleduzzaman, M; Francis, J; Corbin, ME; McIlwain, E; Boudreaux, M; Du, M; Morgan, TW; Peterson, KE,期刊:Journal of virology, 页码:12307-12315 , 文章类型: Article,,卷期:2007年81-22]
- Viral infections of the heart are a causative factor of myocarditis as well as of sudden, unexpected deaths of children, yet the mechanisms of pathogenesis remain unclear, in part due to the relatively few animal models ...
- Influenza virus-induced type I interferon leads to polyclonal B-cell activation but does not break down B-cell tolerance
[作者:Woods, A; Monneaux, F; Soulas-Sprauel, P; Muller, S; Martin, T; Korganow, AS; Pasquali, JL,期刊:Journal of virology, 页码:12525-12534 , 文章类型: Article,,卷期:2007年81-22]
- The link between infection and autoimmunity is not yet well understood. This study was designed to evaluate if an acute viral infection known to induce type I interferon production, like influenza, can by itself be respo...
- A recombinant Sendai virus is controlled by CD4(+) effector T cells responding to a secreted human immunodeficiency virus type 1 envelope glycoprotein
[作者:Brown, SA; Hurwitz, JL; Zirkel, A; Surman, S; Takitnoto, T; Alyrnova, I; Coleclough, C; Portner, A; Doherty, PC; Slobod, KS,期刊:Journal of virology, 页码:12535-12542 , 文章类型: Article,,卷期:2007年81-22]
- The importance of antigen-specific CD4(+) helper T cells in virus infections is well recognized, but their possible role as direct mediators of virus clearance is less well characterized. Here we describe a recombinant S...
- Structure of adeno-associated virus serotype 8, a gene therapy vector
[作者:Nam, HJ; Lane, MD; Padron, E; Gurda, B; McKenna, R; Kohlbrenner, E; Aslanidi, G; Byrne, B; Muzyczka, N; Zolotukhin, S; Agbandje-McKenna, M,期刊:Journal of virology, 页码:12260-12271 , 文章类型: Article,,卷期:2007年81-22]
- Adeno-associated viruses (AAVs) are being developed as gene therapy vectors, and their efficacy could be improved by a detailed understanding of their viral capsid structures. AAV serotype 8 (AAV8) shows a significantly ...
- Characterization of a broadly reactive monoclonal antibody against norovirus genogroups I and II: Recognition of a novel conformational epitope
[作者:Shiota, T; Okame, M; Takanashi, S; Khamrin, P; Takagi, M; Satou, K; Masuoka, Y; Yagyu, F; Shimizu, Y; Kohno, H; Mizuguchi, M; Okitsu, S; Ushijima, H,期刊:Journal of virology, 页码:12298-12306 , 文章类型: Article,,卷期:2007年81-22]
- Norovirus, which belongs to the family Caliciviridae, is one of the major causes of nonbacterial acute gastroenteritis in the world. The main human noroviruses are of genogroup I (GI) and genogroup II (GII), which were s...
- Localization and membrane topology of coronavirus nonstructural protein 4: Involvement of the early secretory pathway in replication
[作者:Oostra, M; te Lintelo, EG; Deijs, M; Verheije, MH; Rottier, PJM; de Haan, CAM,期刊:Journal of virology, 页码:12323-12336 , 文章类型: Article,,卷期:2007年81-22]
- The coronavirus nonstructural proteins (nsp's) derived from the replicase polyproteins collectively constitute the viral replication complexes, which are anchored to double-membrane vesicles. Little is known about the bi...
- The role of NKG2D signaling in inhibition of cytotoxic T-Lymphocyte lysis by the murine cytomegalovirus immunoevasin m152/gp40
[作者:Pinto, AK; Jamieson, AM; Raulet, DH; Hill, AB,期刊:Journal of virology, 页码:12564-12571 , 文章类型: Article,,卷期:2007年81-22]
- Three proteins encoded by murine cytomegalovirus (MCMV)-gp34, encoded by m04 (m04/gp34), gp48, encoded by m06 (m06/gp48), and gp40, encoded by m152 (m152/gp40)-act together to powerfully impact the ability of primed cyto...
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