- Differences in hepatitis C virus (HCV)-specific CD8 T-cell phenotype during pegylated alpha interferon and ribavirin treatment are related to response to antiviral therapy in patients chronically infected with HCV
[作者:Caetano, J; Martinho, A; Paiva, A; Pais, B; Valente, C; Luxo, C,期刊:Journal of virology, 页码:7567-7577 , 文章类型: Article,,卷期:2008年82-15]
- CD8 T cells play a major role in antiviral immune responses. Their importance for progression to chronic hepatitis C and response to treatment are still unclear. To address these issues, hepatitis C virus (HCV)-specific ...
- Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice
[作者:Feng, N; Kim, B; Fenaux, M; Nguyen, H; Vo, P; Omary, MB; Greenberg, HB,期刊:Journal of virology, 页码:7578-7590 , 文章类型: Article,,卷期:2008年82-15]
- Recent studies demonstrated that viremia and extraintestinal rotavirus infection are common in acutely infected humans and animals, while systemic diseases appear to be rare. Intraperitoneal infection of newborn mice wit...
- Mutational analysis of plant cap-binding protein eIF4E reveals key amino acids involved in biochemical functions and potyvirus infection
[作者:German-Retana, S; Walter, J; Doublet, B; Roudet-Tavert, G; Nicaise, V; Lecampion, C; Houvenaghel, MC; Robaglia, C; Michon, T; Le Gall, O,期刊:Journal of virology, 页码:7601-7612 , 文章类型: Article,,卷期:2008年82-15]
- The eukaryotic translation initiation factor 4E (eIF4E) (the cap-binding protein) is involved in natural resistance against several potyviruses in plants. In lettuce, the recessive resistance genes mol(1) and mol(2) agai...
- Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly
[作者:Kong, KF; Delroux, K; Wang, XM; Qian, F; Arjona, A; Malawista, SE; Fikrig, E; Montgomery, RR,期刊:Journal of virology, 页码:7613-7623 , 文章类型: Article,,卷期:2008年82-15]
- West Nile virus (WNV), a mosquito-borne flavivirus, has recently emerged in North America, and the elderly are particularly susceptible to severe neurological disease and death from infection with this virus. We have inv...
- NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly
[作者:Ma, YH; Yates, J; Liang, YQ; Lemon, SM; Yi, MK,期刊:Journal of virology, 页码:7624-7639 , 文章类型: Article,,卷期:2008年82-15]
- A mutation within subdomain 1 of the hepatitis C virus (HCV) NS3 helicase (NS3-Q221L) (M. Yi, Y. Ma, J. Yates, and S. M. Lemon, J. Virol. 81:629-638, 2007) rescues a defect in production of infectious virus by an interge...
- Role for E1B-AP5 in ATR signaling pathways during adenovirus infection
[作者:Blackford, AN; Bruton, RK; Dirlik, O; Stewart, GS; Taylor, AMR; Dobner, T; Grand, RJA; Turnell, AS,期刊:Journal of virology, 页码:7640-7652 , 文章类型: Article,,卷期:2008年82-15]
- E1B-55K-associated protein 5 (E1B-AP5) is a cellular, heterogeneous nuclear ribonucleoprotein that is targeted by adenovirus (Ad) E1B-55K during infection. The function of E1B-AP5 during infection, however, remains large...
- Dengue virus replicon expressing the nonstructural proteins suffices to enhance membrane expression of HLA class I and inhibit lysis by human NK cells
[作者:Hershkovitz, O; Zilka, A; Bar-Ilan, A; Abutbul, S; Davidson, A; Mazzon, M; Kummerer, BM; Monsoengo, A; Jacobs, M; Porgador, A,期刊:Journal of virology, 页码:7666-7676 , 文章类型: Article,,卷期:2008年82-15]
- Many viruses escape the cellular immune response by downregulating cell surface expression of major histocompatibility complex (MHC) class I molecules. However, infection of cells with flaviviruses can upregulate the exp...
- Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: Implications for HIV-1 vaccine design
[作者:Gasper-Smith, N; Crossman, DM; Whitesides, JF; Mensali, N; Ottinger, JS; Plonk, SG; Moody, MA; Ferrari, G; Weinhold, KJ; Miller, SE; Reich, CF; Qin, L; Self, SG; Shaw, GM; Denny, TN; Jones, LE; Pisetsky, DS; Haynes, BF,期刊:Journal of virology, 页码:7700-7710 , 文章类型: Article,,卷期:2008年82-15]
- The death of CD4(+) CCR5(+) T cells is a hallmark of human immunodeficiency virus (HIV) infection. We studied the plasma levels of cell death mediators and products-tumor necrosis factor (TNF)-related apoptosis-inducing ...
- Biodistribution and safety profile of recombinant adeno-associated virus serotype 6 vectors following intravenous delivery
[作者:Stone, D; Liu, Y; Li, ZY; Strauss, R; Finn, EE; Allen, JM; Chamberlain, JS; Lieber, A,期刊:Journal of virology, 页码:7711-7715 , 文章类型: Article,,卷期:2008年82-15]
- Recombinant adeno-associated virus vectors based on serotype 6 (rAAV6) efficiently transduce skeletal muscle after intravenous administration and have shown efficacy in the mdx model of muscular dystrophy. As a prelude t...
- A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in Golden Syrian hamsters
[作者:Lamirande, EW; DeDiego, ML; Roberts, A; Jackson, JP; Alvarez, E; Sheahan, T; Shieh, WJ; Zaki, SR; Baric, R; Enjuanes, L; Subbarao, K,期刊:Journal of virology, 页码:7721-7724 , 文章类型: Article,,卷期:2008年82-15]
- The immunogenicity and protective efficacy of a live attenuated vaccine consisting of a recombinant severe acute respiratory syndrome (SARS) coronavirus lacking the E gene (rSARS-CoV-Delta E) were studied using hamsters....
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