- The effects of alternate polypurine tracts (PPTs) and mutations of sequences adjacent to the PPT on viral replication and cleavage specificity of the Rous sarcoma virus reverse transcriptase
[作者:Chang, KW; Oh, J; Alvord, WG; Hughes, SH,期刊:Journal of virology, 页码:8592-8604 , 文章类型: Article,,卷期:2008年82-17]
- We previously reported that a mutant Rous sarcoma virus (RSV) with an alternate polypurine tract (PPT), DuckHepBFlipPPT, had unexpectedly high titers and that the PPT was miscleaved primarily at one position following a ...
- Higher homologous and lower cross-reactive Gag-specific T-cell responses in human immunodeficiency virus type 2 (HIV-2) than in HIV-1 infection
[作者:Jennes, W; Camara, M; Dieye, T; Mboup, S; Kestens, L,期刊:Journal of virology, 页码:8619-8628 , 文章类型: Article,,卷期:2008年82-17]
- Human immunodeficiency virus type 2 (HIV-2) infection results in slower CD4(+) T-cell decline, lower plasma viral load levels, and hence slower progression of the disease than does HIV-1 infection. Although the reasons f...
- Structure of the main protease from a global infectious human coronavirus, HCoV-HKU1
[作者:Zhao, Q; Li, S; Xue, F; Zou, YL; Chen, C; Bartlam, M; Rao, ZH,期刊:Journal of virology, 页码:8647-8655 , 文章类型: Article,,卷期:2008年82-17]
- The newly emergent human coronavirus HKU1 (HCoV-HKU1) was first identified in Hong Kong in 2005. Infection by HCoV-HKU1 occurs worldwide and causes syndromes such as the common cold, bronchitis, and pneumonia. The CoV ma...
- Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly
[作者:Stanley, BJ; Ehrlich, ES; Short, L; Yu, YK; Xiao, ZX; Yu, XF; Xiong, Y,期刊:Journal of virology, 页码:8656-8663 , 文章类型: Article,,卷期:2008年82-17]
- Human immunodeficiency virus (HIV) virion infectivity factor (Vif) causes the proteasome-mediated destruction of human antiviral protein APOBEC3G by tethering it to a cellular E3 ubiquitin ligase composed of ElonginB, El...
- Vaccinia virus L1 protein is required for cell entry and membrane fusion
[作者:Bisht, H; Weisberg, AS; Moss, B,期刊:Journal of virology, 页码:8687-8694 , 文章类型: Article,,卷期:2008年82-17]
- Genetic and biochemical studies have provided evidence for an entry/fusion complex (EFC) comprised of at least eight viral proteins (A16, A21, A28, G3, G9, H2, J5, and L5) that together with an associated protein (F9) pa...
- Structural domains within the 3 ' untranslated region of Turnip crinkle virus
[作者:McCormack, JC; Yuan, XF; Yingling, YG; Kasprzak, W; Zamora, RE; Shapiro, BA; Simon, AE,期刊:Journal of virology, 页码:8706-8720 , 文章类型: Article,,卷期:2008年82-17]
- The genomes of positive-strand RNA viruses undergo conformational shifts that complicate efforts to equate structures with function. We have initiated a detailed analysis of secondary and tertiary elements within the 3' ...
- Vectorial entry and release of hepatitis a virus in polarized human hepatocytes
[作者:Snooks, MJ; Bhat, P; Mackenzie, J; Counihan, NA; Vaughan, N; Anderson, DA,期刊:Journal of virology, 页码:8733-8742 , 文章类型: Article,,卷期:2008年82-17]
- Hepatitis A virus (HAV) is an enterically transmitted virus that replicates predominantly in hepatocytes within the liver before excretion via bile through feces. Hepatocytes are polarized epithelial cells, and it has be...
- Conserved footprints of APOBEC3G on hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences
[作者:Armitage, AE; Katzourakis, A; de Oliveira, T; Welch, JJ; Belshaw, R; Bishop, KN; Kramer, B; McMichael, AJ; Rambaut, A; Iversen, AKN,期刊:Journal of virology, 页码:8743-8761 , 文章类型: Article,,卷期:2008年82-17]
- The human polynucleotide cytidine deaminases APOBEC3G (hA3G) and APOBEC3F (hA3F) are antiviral restriction factors capable of inducing extensive plus-strand guanine-to-adenine (G-to-A) hypermutation in a variety of retro...
- Experimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus
[作者:Shindler, KS; Kenyon, LC; Dutt, M; Hingley, ST; Das Sarma, J,期刊:Journal of virology, 页码:8882-8886 , 文章类型: Article,,卷期:2008年82-17]
- Optic neuritis (ON), an inflammatory demyelinating optic nerve disease, occurs in multiple sclerosis (MS). Pathological mechanisms and potential treatments for ON have been studied via experimental autoimmune MS models. ...
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