- Potent antibody-mediated neutralization and evolution of antigenic escape variants of simian immunodeficiency virus strain SIVmac239 in vivo
[作者:Sato, S; Yuste, E; Lauer, WA; Chang, EH; Morgan, JS; Bixby, JG; Lifson, JD; Desrosiers, RC; Johnson, WE,期刊:Journal of virology, 页码:9739-9752 , 文章类型: Article,,卷期:2008年82-19]
- Here, we describe the evolution of antigenic escape variants in a rhesus macaque that developed unusually high neutralizing antibody titers to SIVmac239. By 42 weeks postinfection, 50% neutralization of SIVmac239 was ach...
- Ligand-independent exhaustion of killer immunoglobulin-like receptor-positive CD8(+) T cells in human immunodeficiency virus type 1 infection
[作者:Alter, G; Rihn, S; Streeck, H; Teigen, N; Piechocka-Trocha, A; Moss, K; Cohen, K; Meier, A; Pereyra, F; Walker, B; Altfeld, M,期刊:Journal of virology, 页码:9668-9677 , 文章类型: Article,,卷期:2008年82-19]
- Virus-specific CD8(+) T cells play a central role in the control of viral infections, including human immunodeficiency virus type 1 (HIV-1) infection. However, despite the presence of strong and broad HIV-specific CD8(+)...
- Llama-derived single-chain antibody fragments directed to rotavirus VP6 protein possess broad neutralizing activity in vitro and confer protection against diarrhea in mice
[作者:Garaicoechea, L; Olichon, A; Marcoppido, G; Wigdorovitz, A; Mozgovoj, M; Saif, L; Surrey, T; Parreno, V,期刊:Journal of virology, 页码:9753-9764 , 文章类型: Article,,卷期:2008年82-19]
- Group A rotavirus is one of the most common causes of severe diarrhea in human infants and newborn animals. Rotavirus virions are triple-layered particles. The outer capsid proteins VP4 and VP7 are highly variable and re...
- Aichi virus 2A protein is involved in viral RNA replication
[作者:Sasaki, J; Taniguchi, K,期刊:Journal of virology, 页码:9765-9769 , 文章类型: Article,,卷期:2008年82-19]
- The Aichi virus 2A protein is not a protease, unlike many other picornavirus 2A proteins, and it is related to a cellular protein, H-rev107. Here, we examined the replication properties of two 2A mutants in Vero cells an...
- Basal budding and replication of the murine leukemia virus are independent of the Gag L domains
[作者:Sabo, Y; Laham-Karam, N; Bacharach, E,期刊:Journal of virology, 页码:9770-9775 , 文章类型: Article,,卷期:2008年82-19]
- Moloney murine leukemia virus (MMuLV) Gag protein contains three identified late (L) domains, PPPY, YPAL, and PSAP, which are thought to interact with the endosomal sorting machinery to assist budding. We created single ...
- Inhibition of human immunodeficiency virus type 1 assembly and release by the cholesterol-binding compound amphotericin B methyl ester: Evidence for Vpu dependence
[作者:Waheed, AA; Ablan, SD; Soheilian, F; Nagashima, K; Ono, A; Schaffner, CP; Freed, EO,期刊:Journal of virology, 页码:9776-9781 , 文章类型: Article,,卷期:2008年82-19]
- We investigated the mechanism by which the cholesterol- binding compound amphotericin B methyl ester (AME) inhibits human immunodeficiency virus type 1 (HIV-1) particle production. We observed no significant effect of AM...
- The kinetics of hepatitis C virus-specific CD8 T-cell responses in the blood mirror those in the liver in acute hepatitis C virus infection
[作者:Shin, EC; Capone, S; Cortese, R; Colloca, S; Nicosia, A; Folgori, A; Rehermann, B,期刊:Journal of virology, 页码:9782-9788 , 文章类型: Article,,卷期:2008年82-19]
- Peripheral blood T-cell responses are used as biomarkers in hepatitis C virus (HCV) vaccine trials. However, it is not clear how T-cell responses in the blood correlate with those in the liver, the infection site. By stu...
- Cytopathogenicity of classical swine fever virus correlates with attenuation in the natural host
[作者:Gallei, A; Blome, S; Gilgenbach, S; Tautz, N; Moennig, V; Becher, P,期刊:Journal of virology, 页码:9717-9729 , 文章类型: Article,,卷期:2008年82-19]
- For the important livestock pathogens classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV), cytopathogenic (cp) and non-cp viruses are distinguished according to the induction of apoptosis in infecte...
- Gag-specific CD4(+) T-cell frequency is inversely correlated with proviral load and directly correlated with immune activation in infection with human immunodeficiency virus type 2 (HIV-2) but not HIV-1
[作者:Foxall, RB; Cortesao, CS; Albuquerque, AS; Soares, RS; Victorino, RMM; Sousa, AE,期刊:Journal of virology, 页码:9795-9799 , 文章类型: Article,,卷期:2008年82-19]
- Human immunodeficiency virus type 2 (HIV-2) infection, unlike HIV-1 infection, is normally characterized by low rates of CD4 depletion and low-to-undetectable viremia. We found that the frequency of Gag-specific CD4(+) T...
- The F-like protein Ac23 enhances the infectivity of the budded virus of gp64-null Autographa californica multinucleocapsid nucleopolyhedrovirus pseudotyped with baculovirus envelope fusion protein F
[作者:Wang, ML; Tan, Y; Yin, FF; Deng, F; Vlak, JM; Hu, ZH; Wang, HL,期刊:Journal of virology, 页码:9800-9804 , 文章类型: Article,,卷期:2008年82-19]
- The GP64 and F proteins were previously identified as the sole functional envelope fusion proteins in Baculoviridae. F-like proteins, present only in group I nucleopolyhedroviruses (NPVs), are remnant, nonfunctional F pr...
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