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  • Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs
    [作者:Salloum, S; Oniangue-Ndza, C; Neumann-Haefelin, C; Hudson, L; Giugliano, S; Siepen, MAD; Nattermann, J; Spengler, U; Lauer, GM; Wiese, M; Klenerman, P; Bright, H; Scherbaum, N; Thimme, R; Roggendorf, M; Viazov, S; Timm, J,期刊:Journal of virology, 页码:11803-11812 , 文章类型: Article,,卷期:2008年82-23]
  • The inherent sequence diversity of the hepatitis C virus (HCV) represents a major hurdle for the adaptive immune system to control viral replication. Mutational escape within targeted CD8 epitopes during acute HCV infect...