- Asymptomatic Human CD4(+) Cytotoxic T-Cell Epitopes Identified from Herpes Simplex Virus Glycoprotein B
[作者:Chentoufi, AA; Binder, NR; Berka, N; Durand, G; Nguyen, A; Bettahi, I; Maillere, B; BenMohamed, L,期刊:Journal of virology, 页码:11792-11802 , 文章类型: Article,,卷期:2008年82-23]
- The identification of "asymptomatic" (i.e., protective) epitopes recognized by T cells from herpes simplex virus (HSV)-seropositive healthy individuals is a prerequisite for an effective vaccine. Using the PepScan epitop...
- Escape from HLA-B*08-Restricted CD8 T Cells by Hepatitis C Virus Is Associated with Fitness Costs
[作者:Salloum, S; Oniangue-Ndza, C; Neumann-Haefelin, C; Hudson, L; Giugliano, S; Siepen, MAD; Nattermann, J; Spengler, U; Lauer, GM; Wiese, M; Klenerman, P; Bright, H; Scherbaum, N; Thimme, R; Roggendorf, M; Viazov, S; Timm, J,期刊:Journal of virology, 页码:11803-11812 , 文章类型: Article,,卷期:2008年82-23]
- The inherent sequence diversity of the hepatitis C virus (HCV) represents a major hurdle for the adaptive immune system to control viral replication. Mutational escape within targeted CD8 epitopes during acute HCV infect...
- Structural Determinant of Human La Protein Critical for Internal Initiation of Translation of Hepatitis C Virus RNA
[作者:Mondal, T; Ray, U; Manna, AK; Gupta, R; Roy, S; Das, S,期刊:Journal of virology, 页码:11927-11938 , 文章类型: Article,,卷期:2008年82-23]
- Human La protein has been implicated in facilitating internal ribosome entry site (IRES)-mediated translation of hepatitis C virus (HCV). Earlier, we demonstrated that the RNA recognition motif (RRM) encompassing residue...
- Incorporation of Membrane-Anchored Flagellin into Influenza Virus-Like Particles Enhances the Breadth of Immune Responses
[作者:Wang, BZ; Quan, FS; Kang, SM; Bozja, J; Skountzou, I; Compans, RW,期刊:Journal of virology, 页码:11813-11823 , 文章类型: Article,,卷期:2008年82-23]
- We have designed a membrane-anchored form of the Toll-like receptor 5 ligand flagellin, the major proinflammatory determinant of enteropathogenic Salmonella, which was found to be glycosylated and expressed on cell surfa...
- The Proto-Oncogene Bcl3, Induced by Tax, Represses Tax-Mediated Transcription via p300 Displacement from the Human T-Cell Leukemia Virus Type 1 Promoter
[作者:Kim, YM; Sharma, N; Nyborg, JK,期刊:Journal of virology, 页码:11939-11947 , 文章类型: Article,,卷期:2008年82-23]
- The etiology of human T-cell leukemia virus type 1 (HTLV-1)-induced adult T-cell leukemia is linked to the expression of the viral oncoprotein Tax. Although the mechanism of retroviral transformation is unknown, Tax inte...
- Bioinformatic and Physical Characterizations of Genome-Scale Ordered RNA Structure in Mammalian RNA Viruses
[作者:Davis, M; Sagan, SM; Pezacki, JP; Evans, DJ; Simmonds, P,期刊:Journal of virology, 页码:11824-11836 , 文章类型: Article,,卷期:2008年82-23]
By the analysis of thermodynamic RNA secondary structure predictions, we previously obtained evidence for evolutionarily conserved large-scale ordering of RNA virus genomes (P. Simmonds, A. Tuplin, and D.J. Evans, RNA...
- Systematic Assembly of a Full-Length Infectious Clone of Human Coronavirus NL63
[作者:Donaldson, EF; Yount, B; Sims, AC; Burkett, S; Pickles, RJ; Baric, RS,期刊:Journal of virology, 页码:11948-11957 , 文章类型: Article,,卷期:2008年82-23]
- Historically, coronaviruses were predominantly associated with mild upper respiratory disease in humans. More recently, three novel coronaviruses associated with severe human respiratory disease were found, including (i)...
- Critical Role for TSLC1 Expression in the Growth and Organ Infiltration of Adult T-Cell Leukemia Cells In Vivo
[作者:Dewan, MZ; Takamatsu, N; Hidaka, T; Hatakeyama, K; Nakahata, S; Fujisawa, JI; Katano, H; Yamamoto, N; Morishita, K,期刊:Journal of virology, 页码:11958-11963 , 文章类型: Article,,卷期:2008年82-23]
- Adult T-cell leukemia (ATL) is associated with human T-cell leukemia virus type 1 infection. The tumor suppressor lung cancer 1 (TSLC1) gene was previously identified as a novel cell surface marker for ATL, and this stud...
- Murine Coronaviruses Encoding nsp2 at Different Genomic Loci Have Altered Replication, Protein Expression, and Localization
[作者:Gadlage, MJ; Graham, RL; Denison, MR,期刊:Journal of virology, 页码:11964-11969 , 文章类型: Article,,卷期:2008年82-23]
- Partial or complete deletion of several coronavirus nonstructural proteins (nsps), including open reading frame 1a (ORF1a)-encoded nsp2, results in viable mutant proteins with specific replication defects. It is not know...
- Primary Clearance of Murine Gammaherpesvirus 68 by PKC theta(-/-) CD8 T Cells Is Compromised in the Absence of Help from CD4 T Cells
[作者:Dias, P; Shea, AL; Inglis, C; Giannoni, F; Lee, LN; Sarawar, SR,期刊:Journal of virology, 页码:11970-11975 , 文章类型: Article,,卷期:2008年82-23]
- CD4 T cells are dispensable for acute control of murine gammaherpesvirus 68 (MHV-68) but are necessary for effective long-term control of the virus by CD8 T cells. In contrast, protein kinase C theta (PKC theta) is not e...
- Coxsackievirus B4 Uses Autophagy for Replication after Calpain Activation in Rat Primary Neurons
[作者:Yoon, SY; Ha, YE; Choi, JE; Ahn, J; Lee, H; Kweon, HS; Lee, JY; Kim, DH,期刊:Journal of virology, 页码:11976-11978 , 文章类型: Article,,卷期:2008年82-23]
- Coxsackievirus is the most important cause of meningitis and encephalitis in infants; an infection is sometimes fatal or may lead to neurodevelopmental defects. Here, we show that coxsackievirus B4 (CVB4) induces an auto...
- Equine Herpesvirus 1 Entry via Endocytosis Is Facilitated by alpha V Integrins and an RSD Motif in Glycoprotein D
[作者:de Walle, GRV; Peters, ST; VanderVen, BC; O'Callaghan, DJ; Osterrieder, N,期刊:Journal of virology, 页码:11859-11868 , 文章类型: Article,,卷期:2008年82-23]
- Equine herpesvirus 1 (EHV-1) is a member of the Alphaherpesvirinae, and its broad tissue tropism suggests that EHV-1 may use multiple receptors to initiate virus entry. EHV-1 entry was thought to occur exclusively throug...
|