- Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice
[作者:Kim, S; Lalani, S; Parekh, VV; Vincent, TL; Wu, L; Van Kaer, L,期刊:Journal of clinical investigation, 页码:2301-2315 , 文章类型: Article,,卷期:2008年118-6]
- Invariant NKT (iNKT) cells are innate-like lymphocytes that recognize glycolipid antigens in the context of the MHC class I-like antigen-presenting molecule CD1d. In vivo activation of mouse iNKT cells with the glycolipi...
- Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
[作者:Park, JH; Stoffers, DA; Nicholls, RD; Simmons, RA,期刊:Journal of clinical investigation, 页码:2316-2324 , 文章类型: Article,,卷期:2008年118-6]
- Intrauterine growth retardation (IUGR) has been linked to the onset of diseases in adulthood, including type 2 diabetes, and has been proposed to result from altered gene regulation patterns due to epigenetic modificatio...
- Helicobacter pylori induces beta 3GnT5 in human gastric cell lines, modulating expression of the SabA ligand sialyl-Lewis x
[作者:Marcos, NT; Magalhaes, A; Ferreira, B; Oliveira, MJ; Carvalho, AS; Mendes, N; Gilmartin, T; Head, SR; Figueiredo, C; David, L; Santos-Silva, F; Reis, CA,期刊:Journal of clinical investigation, 页码:2325-2336 , 文章类型: Article,,卷期:2008年118-6]
- Chronic Helicobacter pylori infection is recognized as a cause of gastric cancer. H. pylori adhesion to gastric cells is mediated by bacterial adhesins such as sialic acid-binding adhesin (SabA), which binds the carbohyd...
- Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits
[作者:Scheppke, L; Aguilar, E; Gariano, RF; Jacobson, R; Hood, J; Doukas, J; Cao, J; Noronha, G; Yee, S; Weis, S; Martin, MB; Soll, R; Cheresh, DA; Friedlander, M,期刊:Journal of clinical investigation, 页码:2337-2346 , 文章类型: Article,,卷期:2008年118-6]
- Retinal and choroidal vascular diseases, with their associated abnormalities in vascular permeability, account for the majority of patients with vision loss in industrialized nations. VEGF is upregulated in ischemic reti...
- FoxO1 mediates insulin-dependent regulation of hepatic VLDL production in mice
[作者:Kamagate, A; Qu, S; Perdomo, G; Su, D; Kim, DH; Slusher, S; Meseck, M; Dong, HH,期刊:Journal of clinical investigation, 页码:2347-2364 , 文章类型: Article,,卷期:2008年118-6]
- Excessive production of triglyceride-rich VLDL is attributable to hypertriglyceridemia. VLDL production is facilitated by microsomal triglyceride transfer protein (MTP) in a rate-limiting step that is regulated by insuli...
- Impaired microRNA processing causes corpus luteum insufficiency and infertility in mice (vol 118, pg 1944, 2008)
[作者:Otsuka, M; Zheng, M; Hayashi, M; Lee, JD; Yoshino, O; Lin, SC; Han, JH,期刊:Journal of clinical investigation, 页码:2366-2366 , 文章类型: Correction,,卷期:2008年118-6]
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