- Codinaeopsin, an antimalarial fungal polyketide.
[作者:Kontnik, Renee;Clardy, Jon;,期刊:Organic Letters, 页码:4149-4151 , 文章类型: 研究论文,,卷期:2008年10-18]
- A new tryptophan-polyketide hybrid, codinaeopsin, was isolated from an endophytic fungus collected in Costa Rica. The structure of codinaeopsin, which was deduced from NMR and mass spectral data, contains an unusual het...
- Design of a Fluorescent Dye for Indicator Displacement from Cucurbiturils: A Macrocycle-Responsive Fluorescent Switch Operating through a pKa Shift.
[作者:Praetorius, Antonia;Bailey, David M.;Schwarzlose, Thomas;Nau, Werner M.;,期刊:Organic Letters, 页码:4089-4092 , 文章类型: 研究论文,,卷期:2008年10-18]
- anchor affords a fluorescent dye (I) suitable for indicator displacement from cucurbituril macrocycles. The novel compd. I shows, due to a complexation-induced pKa shift, a large and predictable dual fluorescence respon...
- Enantioselective Synthesis of anti-b-Substituted g,d-Unsaturated Amino Acids: A Highly Selective Asymmetric Thio-Claisen Rearrangement.
[作者:Liu, Zhihua;Qu, Hongchang;Gu, Xuyuan;Min, Byoung J.;Nyberg, Joel;Hruby, Victor J.;,期刊:Organic Letters, 页码:4105-4108 , 文章类型: 研究论文,,卷期:2008年10-18]
- A novel synthesis of optically active anti-b-substituted g,d-unsatd. amino acids I (R1 = R2 = R3 = H; R1 = H, R2 = R3 = Me; R1 = Me, R2 = R3 = H; R1 = R2 = H, R3 = Me, Et, Ph) via a thio-Claisen rearrangement has been ac...
- Unusually Stable, Versatile, and Pure Arenediazonium Tosylates: Their Preparation, Structures, and Synthetic Applicability.
[作者:Filimonov, Victor D.;Trusova, Marina;Postnikov, Pavel;Krasnokutskaya, Elena A.;Lee, Young Min;Hwang, Ho Yun;Kim, Hyunuk;Chi, Ki-Whan;,期刊:Organic Letters, 页码:3961-3964 , 文章类型: 研究论文,,卷期:2008年10-18]
- A new, simple, and effective method for the diazotization of a wide range of arylamines has been developed by using a polymer-supported diazotization agent in the presence of p-toluenesulfonic acid. Various pure arenedi...
- A General One-Step Synthesis of b-Nitronitriles.
[作者:Anderson, James C.;Blake, Alexander J.;Mills, Matthew;Ratcliffe, Paul D.;,期刊:Organic Letters, 页码:4141-4143 , 文章类型: 研究论文,,卷期:2008年10-18]
- The unusual b-nitronitrile functionality, e.g. RCH(CYN)CHR1NO2 (R = iso-Pr, cyclohexyl, tert-Bu, R1 = H; R = iso-Pr, n-pentyl, R1 = Et), was prepd. by a simple one-step hydrocyanation of nitroalkenes. These compds. were...
- Practical Heck-Mizoroki Coupling Protocol for Challenging Substrates Mediated by an N-Heterocyclic Carbene-Ligated Palladacycle.
[作者:Kantchev, Eric Assen B.;Peh, Guang-Rong;Zhang, Chi;Ying, Jackie Y.;,期刊:Organic Letters, 页码:3949-3952 , 文章类型: 研究论文,,卷期:2008年10-18]
- A highly active, N-heterocyclic carbene-palladacycle precatalyst I for the Heck-Mizoroki reaction was rationally designed. The complex can be synthesized on a large scale in excellent yield by a novel, one-pot, three-co...
- Preparation of highly photosensitizing liposomes with fullerene-doped lipid bilayer using dispersion-controllable molecular exchange reactions.
[作者:Ikeda, Atsushi;Sue, Tatsuya;Akiyama, Motofusa;Fujioka, Katsuyoshi;Shigematsu, Tamami;Doi, Yuki;Kikuchi, Jun-ichi;Konishi, Toshifumi;Nakajima, Riichiro;,期刊:Organic Letters, 页码:4077-4080 , 文章类型: 研究论文,,卷期:2008年10-18]
- Photochemistry, and Photographic and Other Reprographic Fullerene-contg. liposomes with high photosensitization ability were prepd. Disaggregated fullerenes were efficiently injected into the bilayer of liposomes by a p...
- Synthesis and Activity of Largazole Analogues with Linker and Macrocycle Modification.
[作者:Ying, Yongcheng;Liu, Yanxia;Byeon, Seong Rim;Kim, Hyoungsu;Luesch, Hendrik;Hong, Jiyong;,期刊:Organic Letters, 页码:4021-4024 , 文章类型: 研究论文,,卷期:2008年10-18]
- To characterize largazole's structural requirements for histone deacetylase (HDAC) inhibitory and antiproliferative activities, a series of analogs with modifications to the side chain or 16-membered macrocycle were prep...
- N,N-Acetals as N-Acyliminium Ion Precursors: Synthesis and Absolute Stereochemistry of Epiquinamide.
[作者:Wijdeven, Marloes A.;Wijtmans, Roel;van den Berg, Rutger J. F.;Noorduin, Wim;Schoemaker, Hans E.;Sonke, Theo;van Delft, Floris L.;Blaauw, Richard H.;Fitch, Richard W.;Spande, Thomas F.;Daly, John W.;Rutjes, Floris P. J. T.;,期刊:Organic Letters, 页码:4001-4003 , 文章类型: 研究论文,,卷期:2008年10-18]
- combination with detn. of the abs. configuration of the natural product. Key steps in the sequence involved chemoenzymic formation of enantiomerically pure cyanohydrin II, reductive cyclization to the corresponding cycli...
- Dearomatizing Anionic Cyclization of Phosphonamides. A Route to Phosphonic Acid Derivatives with Antitumor Properties.
[作者:Ruiz-Gomez, Gloria;Francesch, Andres;Jose Iglesias, Maria;Lopez-Ortiz, Fernando;Cuevas, Carmen;Serrano-Ruiz, Manuel;,期刊:Organic Letters, 页码:3981-3984 , 文章类型: 研究论文,,卷期:2008年10-18]
- Deprotonation of bis(N-benzyl-N-methyl)-P-arylphosphonic diamides with s-BuLi in THF at -90?takes place selectively at the benzylic position. The anions undergo intramol. attack to the P-aryl ring leading to dearomatize...
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