- Synthesis of C3-Substituted 4-Azaindoles: An Easy Access to 4-Azamelatonin and Protected 4-Azatryptophan.
[作者:Jeanty, Matthieu;Suzenet, Franck;Guillaumet, Gerald;,期刊:Journal of Organic Chemistry, 页码:7390-7393 , 文章类型: 研究论文,,卷期:2008年73-18]
- C3-Substituted-4-azaindoles, e.g. I (R = CH2Ph, n-Bu, CH2CO2Et, etc.), were synthesized from pyridylacetonitriles, e.g. II, in a two-step sequence allowing the easy introduction of a range of substituents. This strategy ...
- A Novel Synthesis of 2-Functionalized Benzofurans by Palladium-Catalyzed Cycloisomerization of 2-(1-Hydroxyprop-2-ynyl)phenols Followed by Acid-Catalyzed Allylic Isomerization or Allylic Nucleophilic Substitution.
[作者:Gabriele, Bartolo;Mancuso, Raffaella;Salerno, Giuseppe;,期刊:Journal of Organic Chemistry, 页码:7336-7341 , 文章类型: 研究论文,,卷期:2008年73-18]
- A novel two-step synthesis of 2-hydroxymethylbenzofurans I (R = H, R1 = H, Me, R2 = R3 = H; R1 = R3 = H, R2 = OMe; R1 = R2 = H, R3 = OMe, etc.) and 2-alkoxymethylbenzofurans I (R = Me, Bu, PhCH2), based on palladium-cata...
- Palladium-Catalyzed Carbonylation Reactions of Aryl Bromides at Atmospheric Pressure: A General System Based on Xantphos.
[作者:Martinelli, Joseph R.;Watson, Donald A.;Freckmann, Dominique M. M.;Barder, Timothy E.;Buchwald, Stephen L.;,期刊:Journal of Organic Chemistry, 页码:7102-7107 , 文章类型: 研究论文,,卷期:2008年73-18]
- , 27, 28, 29 A method for the Pd-catalyzed carbonylation of aryl bromides has been developed using Xantphos as the ligand. This method is effective for the direct synthesis of Weinreb amides, 1?and 2?benzamides, and Me ...
- Nucleophilic fluoroalkylation of epoxides with fluorinated sulfones.
[作者:[Erratum to document cited in CA145:376984]. Ni, Chuanfa;Li, Ya;Hu, Jinbo;,期刊:Journal of Organic Chemistry, 页码:7440-7440 , 文章类型: 研究论文,,卷期:2008年73-18]
- On page , 6832, in both Table 6 and Scheme 3, the reaction condition "n-BuLi, Et2O" should be changed to "n-BuLi, THF". On page 6833, in the right column, in line 11 from top, the solvent "Et2O" should be changed to "TH...
- The Unexpected Isolation of CTP-431, a Novel Thiopyrone from the Sponge Cacospongia mycofijiensis.
[作者:Johnson, Tyler A.;Amagata, Taro;Oliver, Allen G.;Tenney, Karen;Valeriote, Frederick A.;Crews, Phillip;,期刊:Journal of Organic Chemistry, 页码:7255-7259 , 文章类型: 研究论文,,卷期:2008年73-18]
- A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431. Its structure including abs. configuration as 8R,9R,10S,13S was established usi...
- Dineopentyl Phosphate Hydrolysis: Evidence for Stepwise Water Attack.
[作者:Kamerlin, Shina C. L.;Williams, Nicholas H.;Warshel, Arieh;,期刊:Journal of Organic Chemistry, 页码:6960-6969 , 文章类型: 研究论文,,卷期:2008年73-18]
- in energy prodn., signaling, biosynthesis, and the regulation of protein function among other things. Although the mechanism of action of the enzymes regulating this reaction has been the focus of intensive research in ...
- THAL, a Sterically Unhindered Linker for the Solid-Phase Synthesis of Acid-Sensitive Protected Peptide Acids.
[作者:Isidro-Llobet, Albert;Boas, Ulrik;Jensen, Knud J.;Alvarez, Mercedes;Albericio, Fernando;,期刊:Journal of Organic Chemistry, 页码:7342-7344 , 文章类型: 研究论文,,卷期:2008年73-18]
- 5-(4-Hydroxyphenyl)-3,4-ethylenedioxythienyl alc. (THAL, Thiophene Acid Labile) is described as a new linker for the solid-phase synthesis of peptide carboxylic acids. It is based on the electron-rich 3,4-ethylenedioxyt...
- Investigations of Glycosylation Reactions with 2-N-Acetyl-2N,3O-oxazolidinone-Protected Glucosamine Donors.
[作者:Olsson, Johan D. M.;Eriksson, Lars;Lahmann, Martina;Oscarson, Stefan;,期刊:Journal of Organic Chemistry, 页码:7181-7188 , 文章类型: 研究论文,,卷期:2008年73-18]
- NIS/AgOTf-promoted glycosylation with Et 2,3-N,O-carbonyl-2-deoxy-1-thio-b-D-glucopyranoside donors can be performed with either a- or b-selectivity by tuning the reaction conditions. Small amts. of AgOTf (0.1 equiv) an...
- Straightforward Synthesis of Thiodisaccharides by Ring-Opening of Sugar Epoxides.
[作者:Manzano, Veronica E.;Uhrig, Maria Laura;Varela, Oscar;,期刊:Journal of Organic Chemistry, 页码:7224-7235 , 文章类型: 研究论文,,卷期:2008年73-18]
- 3,4-Anhydro hexopyranosides have been prepd. by diastereoselective epoxidn. of derivs. of 2-Pr 3,4-dideoxy-a-D-erythro-hex-3-enopyranoside (I), selectively protected at HO-2 and HO-6. The allylic group at C-2, in I and ...
- Synthesis and an Evaluation of the Bioactivity of the C-Glycoside of Pseudopterosin A Methyl Ether.
[作者:Zhong, Wei;Moya, Claudia;Jacobs, R. S.;Little, R. Daniel;,期刊:Journal of Organic Chemistry, 页码:7011-7016 , 文章类型: 研究论文,,卷期:2008年73-18]
- synthesis of I, the C-glycoside analog of Pseudopterosin A (PsA) Me ether. This marks the first construction of a C-glycoside for this class of marine natural products, thereby offering an opportunity to compare its bio...
- Generation of Nitrene by the Photolysis of N-Substituted Iminodibenzothiophene.
[作者:Morita, Hiroyuki;Tatami, Atsushi;Maeda, Tetsuo;Ju Kim, Byung;Kawashima, Wataru;Yoshimura, Toshiaki;Abe, Hitoshi;Akasaka, Takeshi;,期刊:Journal of Organic Chemistry, 页码:7159-7163 , 文章类型: 研究论文,,卷期:2008年73-18]
- To evaluate the ability of dibenzothiophene N-substituted sulfilimines as photochem. nitrene sources, their photolyses in the presence of several trapping reagents, such as sulfides, olefins, and phosphorus compds., were...
- Nucleic Acid Structural Engineering Using Pyrene-Functionalized 2'-Amino-a-L-LNA Monomers and Abasic Sites.
[作者:Kumar, T. Santhosh;Madsen, Andreas S.;Ostergaard, Michael E.;Wengel, Jesper;Hrdlicka, Patrick J.;,期刊:Journal of Organic Chemistry, 页码:7060-7066 , 文章类型: 研究论文,,卷期:2008年73-18]
- Oligonucleotides (ONs) modified with a 2'-N-(pyren-1-yl)acetyl-2'-amino-a-L-LNA thymine monomer Y flanked on the 3'-side by an abasic site F (i.e., YF-unit) exhibit unprecedented increases in thermal affinity (DTm values...
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