- G2E3 is a dual function ubiquitin ligase required for early embryonic development
[作者:Brooks, WS; Helton, ES; Banerjee, S; Venable, M; Johnson, L; Schoeb, TR; Kesterson, RA; Crawford, DF,期刊:Journal of Biological Chemistry, 页码:22304-22315 , 文章类型: Article,,卷期:2008年283-32]
- G2E3 is a putative ubiquitin ligase (E3) identified in a microarray screen for mitotic regulatory proteins. It shuttles between the cytoplasm and nucleus, concentrating in nucleoli and relocalizing to the nucleoplasm in ...
- The first structure of dipeptidyl-peptidase III provides insight into the catalytic mechanism and mode of substrate binding
[作者:Baral, PK; Jajcanin-Jozic, N; Deller, S; Macheroux, P; Abramic, M; Gruber, K,期刊:Journal of Biological Chemistry, 页码:22316-22324 , 文章类型: Article,,卷期:2008年283-32]
- Dipeptidyl-peptidases III (DPP III) are zinc-dependent enzymes that specifically cleave the first two amino acids from the N terminus of different length peptides. In mammals, DPP III is associated with important physiol...
- Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor
[作者:Kirk, R; Laman, H; Knowles, PP; Murray-Rust, J; Lomonosov, M; Meziane, EK; McDonald, NQ,期刊:Journal of Biological Chemistry, 页码:22325-22335 , 文章类型: Article,,卷期:2008年283-32]
- F-box proteins are the substrate-recognition components of the Skp1-Cul1-F box protein (SCF) E3 ubiquitin ligases. Here we report a structural relationship between Fbxo7, a component of the SCFFbxo7 E3 ligase, and the pr...
- Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc (vol 283, pg 2724, 2008)
[作者:Alter-Koltunoff, M; Goren, S; Nousbeck, J; Feng, CG; Sher, A; Ozato, K; Azriel, A; Levi, BZ,期刊:Journal of Biological Chemistry, 页码:22336-22336 , 文章类型: Correction,,卷期:2008年283-32]
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- A mutation in telethonin alters Na-v 1.5 function (vol 283, pg 16537, 2008)
[作者:Mazzone, A; Strege, PR; Tester, DJ; Bernard, CE; Faulkner, G; De Giorgio, R; Makielski, JC; Stanghellini, V; Gibbons, SJ; Ackerman, MJ; Farrugia, G,期刊:Journal of Biological Chemistry, 页码:22336-22336 , 文章类型: Correction,,卷期:2008年283-32]
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- Oxidative stress and covalent modification of protein with bioactive aldehydes
[作者:Grimsrud, PA; Xie, HW; Griffin, TJ; Bernlohr, DA,期刊:Journal of Biological Chemistry, 页码:21837-21841 , 文章类型: Review,,卷期:2008年283-32]
- The term "oxidative stress" links the production of reactive oxygen species to a variety of metabolic outcomes, including insulin resistance, immune dysfunction, and inflammation. Antioxidant defense systems down-regulat...
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