- Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from G alpha(12/13) and G alpha(11/q)
[作者:Gavard, J; Gutkind, JS,期刊:Journal of Biological Chemistry, 页码:29888-29896 , 文章类型: Article,,卷期:2008年283-44]
- Increase in vascular permeability occurs under many physiological conditions such as wound repair, inflammation, and thrombotic reactions and is central in diverse human pathologies, including tumor-induced angiogenesis,...
- Interleukin-29 Functions Cooperatively with Interferon to Induce Antiviral Gene Expression and Inhibit Hepatitis C Virus Replication
[作者:Pagliaccetti, NE; Eduardo, R; Kleinstein, SH; Mu, XJ; Bandi, P; Robek, MD,期刊:Journal of Biological Chemistry, 页码:30079-30089 , 文章类型: Article,,卷期:2008年283-44]
- The interferon (IFN)-related cytokine interleukin (IL)-29 (also known as IFN-lambda 1) inhibits virus replication by inducing a cellular antiviral response similar to that activated by IFN-alpha/beta. However, because it...
- Gly-Ala Repeats Induce Position-and Substrate-specific Regulation of 26 S Proteasome-dependent Partial Processing
[作者:Daskalogianni, C; Apcher, S; Candeias, MM; Naski, N; Calvo, F; Fahraeus, R,期刊:Journal of Biological Chemistry, 页码:30090-30100 , 文章类型: Article,,卷期:2008年283-44]
- Partial degradation or regulated ubiquitin proteasome-dependent processing by the 26 S proteasome has been demonstrated, but the underlying molecular mechanisms and the prevalence of this phenomenon remain obscure. Here ...
- MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1
[作者:Miller, TE; Ghoshal, K; Ramaswamy, B; Roy, S; Datta, J; Shapiro, CL; Jacob, S; Majumder, S,期刊:Journal of Biological Chemistry, 页码:29897-29903 , 文章类型: Article,,卷期:2008年283-44]
- We explored the role of microRNAs (miRNAs) in acquiring resistance to tamoxifen, a drug successfully used to treat women with estrogen receptor-positive breast cancer. miRNA microarray analysis of MCF-7 cell lines that a...
- Cell-specific Regulation of PTX3 by Glucocorticoid Hormones in Hematopoietic and Nonhematopoietic Cells
[作者:Doni, A; Mantovani, G; Porta, C; Tuckermann, J; Reichardt, HM; Kleiman, A; Sironi, M; Rubino, L; Pasqualini, F; Nebuloni, M; Signorini, S; Peri, G; Sica, A; Beck-Peccoz, P; Bottazzi, B; Mantovani, A,期刊:Journal of Biological Chemistry, 页码:29983-29992 , 文章类型: Article,,卷期:2008年283-44]
- PTX3 (prototypic long pentraxin 3) is a fluid phase pattern recognition receptor, which plays nonredundant roles in the resistance against diverse pathogens, in the assembly of a hyaluronic acid-rich extracellular matrix...
- Analysis of a Membrane Interacting Region of Herpes Simplex Virus Type 1 Glycoprotein H
[作者:Galdiero, S; Falanga, A; Vitiello, M; Raiola, L; Fattorusso, R; Browne, H; Pedone, C; Isernia, C; Galdiero, M,期刊:Journal of Biological Chemistry, 页码:29993-30009 , 文章类型: Article,,卷期:2008年283-44]
- Glycoprotein H (gH) of herpes simplex virus type I (HSV-1) is involved in the complex mechanism of membrane fusion of the viral envelope with the host cell. Membrane interacting regions and potential fusion peptides have...
- CDKL5 Expression Is Modulated during Neuronal Development and Its Subcellular Distribution Is Tightly Regulated by the C-terminal Tail
[作者:Rusconi, L; Salvatoni, L; Giudici, L; Bertani, I; Kilstrup-Nielsen, C; Broccoli, V; Landsberger, N,期刊:Journal of Biological Chemistry, 页码:30101-30111 , 文章类型: Article,,卷期:2008年283-44]
- Mutations in the human X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been identified in patients with Rett syndrome (RTT), West syndrome, and X-linked infantile spasms, sharing the common feature of mental re...
- High Affinity Interaction between a Bivalve C-type Lectin and a Biantennary Complex-type N-Glycan Revealed by Crystallography and Microcalorimetry
[作者:Gourdine, JP; Cioci, G; Miguet, L; Unverzagt, C; Silva, DV; Varrot, A; Gautier, C; Smith-Ravin, EJ; Imberty, A,期刊:Journal of Biological Chemistry, 页码:30112-30120 , 文章类型: Article,,卷期:2008年283-44]
- Codakine is an abundant 14-kDa mannose-binding C-type lectin isolated from the gills of the sea bivalve Codakia orbicularis. Binding studies using inhibition of hemagglutination indicated specificity for mannose and fuco...
- Mutations M184V and Y115F in HIV-1 Reverse Transcriptase Discriminate against "Nucleotide-competing Reverse Transcriptase Inhibitors"
[作者:Ehteshami, M; Scarth, BJ; Tchesnokov, EP; Dash, C; Le Grice, SFJ; Hallenberger, S; Jochmans, D; Gotte, M,期刊:Journal of Biological Chemistry, 页码:29904-29911 , 文章类型: Article,,卷期:2008年283-44]
- Indolopyridones are potent inhibitors of reverse transcriptase (RT) of the human immunodeficiency virus type 1 (HIV-1). Although the structure of these compounds differs from established nucleoside analogue RT inhibitors...
- Activation-dependent Hindrance of Photoreceptor G Protein Diffusion by Lipid Microdomains
[作者:Wang, Q; Zhang, X; Zhang, L; He, F; Zhang, GW; Jamrich, M; Wensel, TG,期刊:Journal of Biological Chemistry, 页码:30015-30024 , 文章类型: Article,,卷期:2008年283-44]
- The dynamics of G protein-mediated signal transduction depend on the two-dimensional diffusion of membrane-bound G proteins and receptors, which has been suggested to be rate-limiting for vertebrate phototransduction, a ...
- EFA6 Facilitates the Assembly of the Tight Junction by Coordinating an Arf6-dependent and -independent Pathway
[作者:Klein, S; Partisani, M; Franco, M; Luton, F,期刊:Journal of Biological Chemistry, 页码:30129-30138 , 文章类型: Article,,卷期:2008年283-44]
- We have previously reported that EFA6, exchange factor for Arf6, is implicated upon E-cadherin engagement in the process of epithelial cell polarization. We had found that EFA6 acts through stabilization of the apical ac...
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