- De novo chemoenzymatic synthesis of sialic acid
[作者:STALLFORTH PIERRE; MATTHIES STEFAN; ADIBEKIAN ALEXANDER; GILLINGHAM DENNIS G; HILVERT DONALD; SEEBERGER PETER H,期刊:Chemical Communications, 页码:11987-11989 , 文章类型: Article,,卷期:2012年48-98]
- A chemoenzymatic synthesis of sialic acid from inexpensive N-acetyl-D-glucosamine is described. In a three-step Wittig-protection-ozonolysis strategy manno-configured aldehydes are obtained. Treatment with oxaloacetate i...
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