- Implantation Site and Lesion Topology Determine Efficacy of a Human Neural Stem Cell Line in a Rat Model of Chronic Stroke
[作者:Smith, EJ; Stroemer, RP; Gorenkova, N; Nakajima, M; Crum, WR; Tang, E; Stevanato, L; Sinden, JD; Modo, M,期刊:Stem Cells, 页码:785-796 , 文章类型: Article,,卷期:2012年30-4]
- Stroke remains one of the most promising targets for cell therapy. Thorough preclinical efficacy testing of human neural stem cell (hNSC) lines in a rat model of stroke (transient middle cerebral artery occlusion) is, ho...
- Tumor-Initiating Label-Retaining Cancer Cells in Human Gastrointestinal Cancers Undergo Asymmetric Cell Division
[作者:Xin, HW; Hari, DM; Mullinax, JE; Ambe, CM; Koizumi, T; Ray, S; Anderson, AJ; Wiegand, GW; Garfield, SH; Thorgeirsson, SS; Avital, I,期刊:Stem Cells, 页码:591-598 , 文章类型: Article,,卷期:2012年30-4]
- Label-retaining cells (LRCs) have been proposed to represent adult tissue stem cells. LRCs are hypothesized to result from either slow cycling or asymmetric cell division (ACD). However, the stem cell nature and whether ...
- Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease
[作者:Jiang, Y; Cowley, SA; Siler, U; Melguizo, D; Tilgner, K; Browne, C; Dewilton, A; Przyborski, S; Saretzki, G; James, WS; Seger, RA; Reichenbach, J; Lako, M; Armstrong, L,期刊:Stem Cells, 页码:599-611 , 文章类型: Article,,卷期:2012年30-4]
- Chronic granulomatous disease (CGD) is an inherited disorder of phagocytes in which NADPH oxidase is defective in generating reactive oxygen species. In this study, we reprogrammed three normal unrelated patient's fibrob...
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