- Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol
[作者：Stein, EA; Mellis, S; Yancopoulos, GD; Stahl, N; Logan, D; Smith, WB; Lisbon, E; Gutierrez, M; Webb, C; Wu, R; Du, YL; Kranz, T; Gasparino, E; Swergold, GD,期刊：New England Journal of Medicine, 页码：1108-1118 , 文章类型： Article，,卷期：2012年366-12]
- BACKGROUND Proprotein convertase subtilisin/kexin 9 (PCSK9), one of the serine proteases, binds to low-density lipoprotein (LDL) receptors, leading to their accelerated degradation and to increased LDL cholesterol levels...
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