- Terpenoids from Chloranthus serratus and Their Anti-inflammatory Activities
[作者:Zhang, M; Iinuma, M; Wang, JS; Oyama, M; Ito, T; Kong, LY,期刊:Journal of natural products, 页码:694-698 , 文章类型: Article,,卷期:2012年75-4]
- Seven new terpenoids, including two sesquiterpene dimers (1, 2), two norditerpenoids (3, 4), and three sesquiterpenes (5-7), along with six known sesquiterpene dimers and four known sesquiterpenes were isolated from the ...
- Hesperetin Upregulates ABCA1 Expression and Promotes Cholesterol Efflux from THP-1 Macrophages
[作者:Iio, A; Ohguchi, K; Iinuma, M; Nozawa, Y; Ito, M,期刊:Journal of natural products, 页码:563-566 , 文章类型: Article,,卷期:2012年75-4]
- ABCA1, a member of the ATP-binding cassette transporter family, regulates high-density lipoprotein (HDL) metabolism and cholesterol transport. Its expression is upregulated mainly by the activation of the liver X recepto...
- Immunosuppressive Decalin Derivatives from Red Yeast Rice
[作者:Zhu, L; Lu, JG; Li, T; Zhu, GY; Han, QB; Hsiao, WL; Liu, L; Jiang, ZH,期刊:Journal of natural products, 页码:567-571 , 文章类型: Article,,卷期:2012年75-4]
- Five new decalin derivatives (1-5), together with two known compounds (6 and 7), were isolated from the ethyl acetate extract of red yeast rice. Their structures were elucidated by means of NMR and mass spectroscopic ana...
- Isodesacetyluvaricin, an Annonaceous Acetogenin, Specifically Inhibits Gene Expression of Cyclooxygenase-2
[作者:Wu, TY; Yang, IH; Tsai, YT; Wang, JY; Shiurba, R; Hsieh, TJ; Chang, FR; Chang, WC,期刊:Journal of natural products, 页码:572-576 , 文章类型: Article,,卷期:2012年75-4]
- Cyclooxygenase-2 (COX-2) is an inducible isoform of the enzyme responsible for the synthesis of several inflammatory mediators. In a search for phytochemicals with anti-inflammatory activity, the COX-2 inhibitory activit...
- Stellettin A Induces Endoplasmic Reticulum Stress in Murine B16 Melanoma Cells
[作者:Liu, WK; Ling, YH; Cheung, FWK; Che, CT,期刊:Journal of natural products, 页码:586-590 , 文章类型: Article,,卷期:2012年75-4]
- Isomalabaricanes are a small class of rearranged triterpenoids obtained from marine sponges. Most of these are cytotoxic to tumor cells, but the underlying mechanism is not clear. In this study, it was demonstrated that ...
- Isoprenylated Flavonoid and Adipogenesis-Promoting Constituents of Dodonaea viscosa
[作者:Zhang, LB; Ji, J; Lei, C; Wang, HY; Zhao, QS; Hou, AJ,期刊:Journal of natural products, 页码:699-706 , 文章类型: Article,,卷期:2012年75-4]
- Ten new isoprenylated flavonol derivatives, dodoviscins A-J (1-10), and seven known compounds (11-17) were isolated from the aerial parts of Dodonaea viscosa. Compounds 1, 2, 4, 5, 7-9, 5,7,4'-trihydroxy-3',5'-bis(3-meth...
- Waikialoid A Suppresses Hyphal Morphogenesis and Inhibits Biofilm Development in Pathogenic Candida albicans
[作者:Wang, XR; You, JL; King, JB; Powell, DR; Cichewicz, RH,期刊:Journal of natural products, 页码:707-715 , 文章类型: Article,,卷期:2012年75-4]
- A chemically prolific strain of Aspergillus was isolated from a soil sample collected near Waikiki Beach, Honolulu, Hawaii. The fungus produced several secondary metabolites, which were purified and placed in our natural...
- Selective Inhibition of Human Type-5 17 beta-Hydroxysteroid Dehydrogenase (AKR1C3) by Baccharin, a Component of Brazilian Propolis
[作者:Endo, S; Matsunaga, T; Kanamori, A; Otsuji, Y; Nagai, H; Sundaram, K; El-Kabbani, O; Toyooka, N; Ohta, S; Hara, A,期刊:Journal of natural products, 页码:716-721 , 文章类型: Article,,卷期:2012年75-4]
- The human aldo-keto reductase (AKR) 1C3, also known as type-5, 17 beta-hydrogenase and prostaglandin F-synthase has been suggested as a therapeutic target in the treatment of prostate and breast cancers.In this study,AKR...
- Cytotoxic Diterpenoids from Sapium insigne
[作者:Liu, HB; Zhang, H; Yu, JH; Xu, CH; Ding, J; Yue, JM,期刊:Journal of natural products, 页码:722-727 , 文章类型: Article,,卷期:2012年75-4]
- Chemical investigation into the twigs and leaves of Sapium insigne afforded seven new diterpenoids, sapinsignoids A-G (1-7), together with 10 known diterpenoids. The structures of 1-7 were assigned on the basis of detail...
- Bis-spirolabdane Diterpenoids from Leonotis nepetaefolia
[作者:Li, J; Fronczek, FR; Ferreira, D; Burandt, CL; Setola, V; Roth, BL; Zjawiony, JK,期刊:Journal of natural products, 页码:728-734 , 文章类型: Article,,卷期:2012年75-4]
- Ten new bis-spirolabdane diterpenoids, leonepetaefolins A-E (1, 3, 5, 7, 9) and 15-epi-leonepetaefolins A-E (2, 4, 6, 8, 10), together with eight known labdane diterpenoids (11-18) as well as two known flavonoids, apigen...
- Peptidolipins B-F, Antibacterial Lipopeptides from an Ascidian-Derived Nocardia sp.
[作者:Wyche, TP; Hou, YP; Vazquez-Rivera, E; Braun, D; Bugni, TS,期刊:Journal of natural products, 页码:735-740 , 文章类型: Article,,卷期:2012年75-4]
- A marine Nocardia sp. isolated from the ascidian Trididemnum orbiculatum was found to produce five new lipopeptides, peptidolipins B-F (1-5), which show distinct similarities to the previously reported L-Val(6) analog of...
- Cycloartane and Friedelane Triterpenoids from the Leaves of Caloncoba glauca and Their Evaluation for Inhibition of 11 beta-Hydroxysteroid Dehydrogenases
[作者:Mpetga, JDS; Shen, Y; Tane, P; Li, SF; He, HP; Wabo, HK; Tene, M; Leng, Y; Hao, XJ,期刊:Journal of natural products, 页码:599-604 , 文章类型: Article,,卷期:2012年75-4]
- Five new triterpenoids, caloncobic acids A and B (1 and 2), caloncobalactones A and B (3 and 4), and glaucalactone (5), along with the known compounds 3 beta,21 beta-dihydroxy-30-nor-(D:A)-friedo-olean-20(29)-en-27-oic a...
- Phenanthrene Derivatives from Cymbidium Great Flower Marie Laurencin and Their Biological Activities
[作者:Yoshikawa, K; Ito, T; Iseki, K; Baba, C; Imagawa, H; Yagi, Y; Morita, H; Asakawa, Y; Kawano, S; Hashimoto, T,期刊:Journal of natural products, 页码:605-609 , 文章类型: Article,,卷期:2012年75-4]
- A new phenanthrendione, ephemeranthoquinone B (1), two phenanthrenes, marylaurencinols A (2) and B (3), and a phenanthrene glucoside, marylaurencinoside A (4), Laurencin, along with six known phenanthrenes, 5-10. The wer...
- Falcarindiol Allosterically Modulates GABAergic Currents in Cultured Rat Hippocampal Neurons
[作者:Wyrembek, P; Negri, R; Kaczor, P; Czyzewska, M; Appendino, G; Mozrzymas, JW,期刊:Journal of natural products, 页码:610-616 , 文章类型: Article,,卷期:2012年75-4]
- Falcarindiol (1), a C-17 polyacetylenic diol, shows a pleiotropic profile of bioactivity, but the mechanism(s) underlying its actions are largely unknown. Large amounts of 1 co-occur in water hemlock (Oenanthe crocata) a...
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