- H2O2-Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca2+-Activated K+ Channel Activation
[作者:Zhang, DX; Borbouse, L; Gebremedhin, D; Mendoza, SA; Zinkevich, NS; Li, RS; Gutterman, DD,期刊:Circulation Research, 页码:471-U227 , 文章类型: Article,,卷期:2012年110-3]
- Rationale: Hydrogen peroxide (H2O2) serves as a key endothelium-derived hyperpolarizing factor mediating flow-induced dilation in human coronary arterioles (HCAs). The precise mechanisms by which H2O2 elicits smooth musc...
- Developing MicroRNA Therapeutics
[作者:van Rooij, E; Purcell, AL; Levin, AA,期刊:Circulation Research, 页码:496-507 , 文章类型: Review,,卷期:2012年110-3]
- Rarely a new research area has gotten such an overwhelming amount of attention as have microRNAs. Although several basic questions regarding their biological principles still remain to be answered, many specific characte...
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