- Genetic Modification of the O-Polysaccharide of Francisella tularensis Results in an Avirulent Live Attenuated Vaccine
[作者:Kim, TH; Pinkham, JT; Heninger, SJ; Chalabaev, S; Kasper, DL,期刊:Journal of Infectious Diseases, 页码:1056-1065 , 文章类型: Article,,卷期:2012年205-7]
- Background. Francisella tularensis, the causative agent of tularemia, is a highly virulent microbe. One significant virulence factor of F. tularensis is the O-polysaccharide (O-PS) portion of the organism's lipopolysacch...
- Genetically Associated CD16(+)56(-) Natural Killer Cell Interferon (IFN)-alpha R Expression Regulates Signaling and Is Implicated in IFN-alpha-Induced Hepatitis C Virus Decline
[作者:Conry, SJ; Meng, QL; Hardy, G; Yonkers, NL; Sugalski, JM; Hirsch, A; Davitkov, P; Compan, A; Falck-Ytter, Y; Blanton, RE; Rodriguez, B; Harding, CV; Anthony, DD,期刊:Journal of Infectious Diseases, 页码:1131-1141 , 文章类型: Article,,卷期:2012年205-7]
- Background. Natural killer (NK) cells likely contribute to outcome of acute hepatitis C virus (HCV) infection and interferon (IFN)-induced control of chronic HCV infection. We previously observed IFN-alpha R and NKp30 ex...
- Platelets Enhance Biofilm Formation and Resistance of Endocarditis-Inducing Streptococci on the Injured Heart Valve
[作者:Jung, CJ; Yeh, CY; Shun, CT; Hsu, RB; Cheng, HW; Lin, CS; Chia, JS,期刊:Journal of Infectious Diseases, 页码:1066-1075 , 文章类型: Article,,卷期:2012年205-7]
- Infective endocarditis is a typical biofilm-associated infectious disease frequently caused by commensal streptococci, but the contribution of host factors in biofilm formation is unclear. We found that platelets are ess...
- Polymorphisms in the Gene That Encodes the Iron Transport Protein Ferroportin 1 Influence Susceptibility to Tuberculosis
[作者:Baker, MA; Wilson, D; Wallengren, K; Sandgren, A; Iartchouk, O; Broodie, N; Goonesekera, SD; Sabeti, PC; Murray, MB,期刊:Journal of Infectious Diseases, 页码:1043-1047 , 文章类型: Article,,卷期:2012年205-7]
- Background. We studied the association between iron intake and polymorphisms in the iron transporter gene SLC40A1 and the risk of tuberculosis. Methods. We compared iron intake, the frequency of SLC40A1 mutations, and in...
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