- Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1
[作者:Chung, WG; Sandoval, MA; Sloat, BR; Lansakara, DSP; Cui, ZR,期刊:Journal of controlled release, 页码:132-140 , 文章类型: Article,,卷期:2012年157-1]
- Gemcitabine is a deoxycytidine analog used in the treatment of various solid tumors. However, tumors often develop resistances over time, which becomes a major issue for most gemcitabine-related chemotherapies. In the pr...
- Design of an inhalable dry powder formulation of DOTAP-modified PLGA nanoparticles loaded with siRNA
[作者:Jensen, DK; Jensen, LB; Koocheki, S; Bengtson, L; Cun, DM; Nielsen, HM; Foged, C,期刊:Journal of controlled release, 页码:141-148 , 文章类型: Article,,卷期:2012年157-1]
- Matrix systems based on biocompatible and biodegradable polymers like the United States Food and Drug Administration (FDA)-approved polymer poly(DL-lactide-co-glycolide acid) (PLGA) are promising for the delivery of smal...
- Dry powders based on PLGA nanoparticles for pulmonary delivery of antibiotics: Modulation of encapsulation efficiency, release rate and lung deposition pattern by hydrophilic polymers
[作者:Ungaro, F; d'Angelo, I; Coletta, C; Bianca, RDD; Sorrentino, R; Perfetto, B; Tufano, MA; Miro, A; La Rotonda, MI; Quaglia, F,期刊:Journal of controlled release, 页码:149-159 , 文章类型: Article,,卷期:2012年157-1]
- Although few experimental studies have been handled so far to exploit the potential of poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) in the production of dry powders for antibiotic inhalation, there has been n...
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