- Efficient CRM197-mediated drug targeting to monocytes
[作者：Schenk, GJ; Haasnoot, PCJ; Centlivre, M; Legrand, N; Rip, J; de Boer, AG; Berkhout, B,期刊：Journal of controlled release, 页码：139-147 , 文章类型： Article，,卷期：2012年158-1]
- Efficient delivery of drugs to specific cellular reservoirs is of particular importance for therapeutics that are not able to pass cellular barriers and that may have unwanted side effects in off-target tissues. Heparin-...
- Rapid tumoritropic accumulation of systemically injected plateloid particles and their biodistribution
[作者：van de Ven, AL; Kim, P; Haley, O; Fakhoury, JR; Adriani, G; Schmulen, J; Moloney, P; Hussain, F; Ferrari, M; Liu, XW; Yun, SH; Decuzzi, P,期刊：Journal of controlled release, 页码：148-155 , 文章类型： Article，,卷期：2012年158-1]
- Nanoparticles for cancer therapy and imaging are designed to accumulate in the diseased tissue by exploiting the Enhanced Permeability and Retention (EPR) effect. This limits their size to about 100 nm. Here, using intra...
- Poly(glycerol adipate)-fatty acid esters as versatile nanocarriers: From nanocubes over ellipsoids to nanospheres
[作者：Weiss, VM; Naolou, T; Hause, G; Kuntsche, J; Kressler, J; Mader, K,期刊：Journal of controlled release, 页码：156-164 , 文章类型： Article，,卷期：2012年158-1]
- Poly(glycerol adipate) (PGA) is a biodegradable polymer with promising features for nanoparticulate drug carrier systems. By acylation of PGA with fatty acids, composite systems with amphiphilic properties can be obtaine...
- Hydrogel-electrospun fiber composite materials for hydrophilic protein release
[作者：Han, N; Johnson, J; Lannutti, JJ; Winter, JO,期刊：Journal of controlled release, 页码：165-170 , 文章类型： Article，,卷期：2012年158-1]
- Although hydrogels are widely used in controlled-release systems, obtaining extended, uniform drug release with little initial burst has been challenging. However, recently researchers have shown that combining hydrogels...
- Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy
[作者：Stone, E; Chantranupong, L; Gonzalez, C; O'Neal, J; Rani, M; VanDenBerg, C; Georgiou, G,期刊：Journal of controlled release, 页码：171-179 , 文章类型： Article，,卷期：2012年158-1]
- Systemic L-arginine depletion following intravenous administration of L-arginine hydrolyzing enzymes has been shown to selectively impact tumors displaying urea cycle defects including a large fraction of hepatocellular ...
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