- BEAM: A Randomized Phase II Study Evaluating the Activity of Bevacizumab in Combination With Carboplatin Plus Paclitaxel in Patients With Previously Untreated Advanced Melanoma
[作者:Kim, KB; Sosman, JA; Fruehauf, JP; Linette, GP; Markovic, SN; McDermott, DF; Weber, JS; Nguyen, H; Cheverton, P; Chen, D; Peterson, AC; Carson, WE; O'Day, SJ,期刊:Journal of clinical oncology, 页码:34-41 , 文章类型: Article,,卷期:2012年30-1]
- Purpose Metastatic melanoma, a highly vascularized tumor with strong expression of vascular endothelial growth factor, has an overall poor prognosis. We conducted a placebo-controlled, double-blind phase II study of carb...
- Breast Cancer Prognosis in BRCA1 and BRCA2 Mutation Carriers: An International Prospective Breast Cancer Family Registry Population-Based Cohort Study
[作者:Goodwin, PJ; Phillips, KA; West, DW; Ennis, M; Hopper, JL; John, EM; O'Malley, FP; Milne, RL; Andrulis, IL; Friedlander, ML; Southey, MC; Apicella, C; Giles, GG; Longacre, TA,期刊:Journal of clinical oncology, 页码:19-26 , 文章类型: Article,,卷期:2012年30-1]
- Purpose To compare breast cancer prognosis in BRCA1 and BRCA2 mutation carriers with that in patients with sporadic disease. Patients and Methods An international population-based cohort study was conducted in Canada, th...
- Genetic Disease in the Children of Danish Survivors of Childhood and Adolescent Cancer
[作者:Winther, JF; Olsen, JH; Wu, HY; Shyr, Y; Mulvihill, JJ; Stovall, M; Nielsen, A; Schmiegelow, M; Boice, JD,期刊:Journal of clinical oncology, 页码:27-33 , 文章类型: Article,,卷期:2012年30-1]
- Purpose Preconception radiation and chemotherapy have the potential to produce germ cell mutations leading to genetic disease in the next generation. Dose-response relationships were evaluated between cancer treatments a...
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