- E-cadherin inhibits nuclear accumulation of Nrf2: implications for chemoresistance of cancer cells
[作者:Kim, WD; Kim, YW; Cho, IJ; Lee, CH; Kim, SG,期刊:Journal of cell science, 页码:1284-1295 , 文章类型: Article,,卷期:2012年125-5]
- Nrf2 has an anti-carcinogenic effect. However, an increase in Nrf2 activity is also implicated in cancer chemoresistance. A switch from E-cadherin to N-cadherin affects the transdifferentiation and metastasis of cancer c...
- Samp1 is a component of TAN lines and is required for nuclear movement
[作者:Borrego-Pinto, J; Jegou, T; Osorio, DS; Aurade, F; Gorjanaacz, M; Koch, B; Mattaj, IW; Gomes, ER,期刊:Journal of cell science, 页码:1099-1105 , 文章类型: Article,,卷期:2012年125-5]
- The position of the nucleus is regulated in different developmental stages and cellular events. During polarization, the nucleus moves away from the future leading edge and this movement is required for proper cell migra...
- Slow-dividing satellite cells retain long-term self-renewal ability in adult muscle
[作者:Ono, Y; Masuda, S; Nam, HS; Benezra, R; Miyagoe-Suzuki, Y; Takeda, S,期刊:Journal of cell science, 页码:1309-1317 , 文章类型: Article,,卷期:2012年125-5]
- Satellite cells are muscle stem cells that have important roles in postnatal muscle growth and adult muscle regeneration. Although fast-and slow-dividing populations in activated satellite cells have been observed, the f...
- Altered nanofeature size dictates stem cell differentiation
[作者:Zouani, OF; Chanseau, C; Brouillaud, B; Bareille, R; Deliane, F; Foulc, MP; Mehdi, A; Durrieu, MC,期刊:Journal of cell science, 页码:1217-1224 , 文章类型: Article,,卷期:2012年125-5]
- The differentiation of stem cells can be modulated by physical factors such as the micro-and nano-topography of the extracellular matrix. One important goal in stem cell research is to understand the concept that directs...
- LIMK2 is a crucial regulator and effector of Aurora-A-kinase-mediated malignancy
[作者:Johnson, EO; Chang, KH; Ghosh, S; Venkatesh, C; Giger, K; Low, PS; Shah, K,期刊:Journal of cell science, 页码:1204-1216 , 文章类型: Article,,卷期:2012年125-5]
- Aurora A is overexpressed in majority of breast carcinomas. With the exception of BRCA1 and PHLDA1, no oncogenic Aurora A substrates are known in breast cancer. In this study, a chemical genetic approach was used to iden...
- STIL is required for centriole duplication in human cells
[作者:Vulprecht, J; David, A; Tibelius, A; Castiel, A; Konotop, G; Liu, FY; Bestvater, F; Raab, MS; Zentgraf, H; Izraeli, S; Kramer, A,期刊:Journal of cell science, 页码:1353-1362 , 文章类型: Article,,卷期:2012年125-5]
- Centrioles are key structural elements of centrosomes and primary cilia. In mammals, only a few proteins including PLK4, CPAP (CENPJ), SAS6, CEP192, CEP152 and CEP135 have thus far been identified to be required for cent...
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